Saliva Tgfβ1 level in patients with type 2 diabetes mellitus and primary hypertension on dental caries

Masriadi Masriadi; Nur Najma Tasyah; Sari Aldilawati; Muhammad Fajrin Wijaya; Tuti Alawiyah; Ratih Widyastuti; Sri Lestari

doi:10.53730/ijhs.v6n2.11015

Authors

Masriadi
arimasriadi@gmail.com
Universitas Muslim Indonesia, Makassar. Indonesia
Nur Najma Tasyah Universitas Muslim Indonesia, Makassar, Indonesia
Sari Aldilawati Universitas Muslim Indonesia, Makassar, Indonesia
Muhammad Fajrin Wijaya Universitas Muslim Indonesia, Makassar, Indonesia
Tuti Alawiyah Universitas Prof. Dr Moestopo Beragama, Jakarta, Indonesia
Ratih Widyastuti Universitas Prof. Dr Moestopo Beragama, Jakarta, Indonesia
Sri Lestari Trisakti University, Indonesia, Jakarta

Keywords:

dental caries, primary hypertension, saliva, TGFβ1 levels, type 2 diabetes mellitus

Abstract

The aim of this study is to analyze the relationship and differences in salivary Tgfβ1 levels in patients with type 2 diabetes mellitus (T2DM) and primary hypertension (PH) with dental caries patients. Salivary TGFβ1 levels of patients with T2DM & Caries, PH with dental caries were 577.85 pg/ml (0.042) and 386.3894 pg/ml (0.024). Then continued with testing the effect of TGFβ1 on T2DM and PH patients with dental caries, namely T2DM patients (p. 0.042) and PH patients (p. 0.024). This shows that there is a significant effect between salivary TGFβ1 levels of T2DM and PH patients on dental caries. Likewise, it was found that there was a significant difference between T2DM and PH in dental caries by looking at the average value of salivary TGFβ1 on PH was 386,3894pg/mL while salivary TGFβ1 on T2D was 577,8546pg/mL. It can also be seen from the standard deviation value of T2DM deviation is 173.04621, while HTP is 95.93092. There is associated and difference of Salivary TGFβ1 levels of patients with T2DM and PH at the age of 18-40 years with dental caries. The higher the salivary TGFβ1 level, the higher the risk of dental caries.

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