Validity of neutrophil lymphocyte count ratio in neonatal sepsis

Heriyanto Lim; Made Sukmawati; Wayan Dharma Artana; Made Kardana; Putu Junara Putra

doi:10.29332/ijhs.v5n2.1148

Authors

Heriyanto Lim
dr.heriyanto@gmail.com
Department of Child Health, Medical School of Udayana Univesity, Denpasar, Indonesia
Made Sukmawati Department of Child Health, Medical School of Udayana Univesity, Denpasar, Indonesia
Wayan Dharma Artana Department of Child Health, Medical School of Udayana Univesity, Denpasar, Indonesia
Made Kardana Department of Child Health, Medical School of Udayana Univesity, Denpasar, Indonesia
Putu Junara Putra Department of Child Health, Medical School of Udayana Univesity, Denpasar, Indonesia

Keywords:

neonatal sepsis, neutrophil lymphocyte count ratio, procalcitonin

Abstract

Sepsis is a major problem in neonatal care that has not been resolved. This condition is becoming one of major cause of morbidity and mortality in neonates especially in developing countries. Neutrophil lymphocytes count ratio (NLCR) is a new marker of infection that is easy, rapid method and less expensive that can be done in limited health care facilities. A retrospective study with cross sectional design was conducted on 84 neonates with sepsis. The data was collected from medical records from April 2018 to September 2018 in Perinatology Division Sanglah hospital. ROC curve is was done to determine the value cut-off point, sensitivity and specificity of NLCR. With cut-off point of 2.31 NLCR has prevalence, sensitivity, specificity, positive predictive value (PPV) and negative pedictive value (NPV) of 26.1%, 81.8%, 66.1%, 46.1% and 91.1%. NLCR is potential to be used in the diagnosis of neonatal sepsis.

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