Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species
Keywords:
Clove leaf essential oil (Syzygium aromaticum L.), Eugenol, Antifungal, HIV/AIDSAbstract
Candida species are causative microorganisms of oropharyngeal, vulvovaginal, and skin infections. Clove (Syzygium aromaticum L.) and eugenol oil have considerable antifungal activity against human pathogenic fungi, including Candida species. The anticandidal action of the studied oils is significantly dependent on the concentration of eugenol and further main and minor constituents of the oils with well-known antifungal effects must have additional and synergistic activities. This study was conducted to compare the antifungal activity of clove leaf essential oil (Syzygium aromaticum L.) and eugenol to determine the role of the content other than eugenol in clove leaf essential oil as an antifungal against Candida species isolates from HIV-AIDS patients. Methods: This study is an in vitro test using the disk diffusion method to determine the zone of inhibition of clove leaf essential oil (Syzygium aromaticum L.) concentrations of 5%, 10%, and 15% as well as eugenol which was equivalent to the concentration of eugenol in clove leaf essential oil at concentrations of 5%, 10% and 15% in 40 isolates of Candida species.
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Bhuiyan, N. I., Begum, J., Nandi, N. C., & Akter, F. (2010). Constituents of the essential oil from leaves and buds of clove (Syzigium caryophyllatum (L.) Alston). African Journal of Plant Science, 4(11), 451–454. Retrieved from http://www.researchgate.net/publication/228673419_Constituents_of_the_essential_oil_from_leaves_and_buds_of_clove_(Syzigium_caryophyllatum_(L.)_Alston)
Costa, M., Silva, A., Silva, A., Lima, V., Bezerra-Silva, P., Rocha, S., … Paiva, P. (2017). Essential Oils from Leaves of Medicinal Plants of Brazilian Flora: Chemical Composition and Activity against Candida Species. Medicines, 4(2), 27. https://doi.org/10.3390/medicines4020027
Gupta, C., & Prakash, D. (2021). Comparative Study of the Antimicrobial Activity of Clove Oil and Clove Extract on Oral Pathogens. Dentistry – Open Journal, 7(1), 12–15. https://doi.org/10.17140/doj-7-144
Jafri, H., Banerjee, G., Khan, M. S. A., Ahmad, I., Abulreesh, H. H., & Althubiani, A. S. (2020). Synergistic interaction of eugenol and antimicrobial drugs in eradication of single and mixed biofilms of Candida albicans and Streptococcus mutans. AMB Express, 10(1). https://doi.org/10.1186/s13568-020-01123-2
Khalil, A. A., Rahman, U. U., Khan, M. R., Sahar, A., Mehmood, T., & Khan, M. (2017). Essential oil eugenol: Sources, extraction techniques and nutraceutical perspectives. RSC Advances, 7(52), 32669–32681. https://doi.org/10.1039/c7ra04803c
Megawati, R. F., Da’i, M., & Munawaroh, R. (2010). Quality Analysis of Clove Bud Essential Oils (Syzygium Aromaticum (L.) Meer. &Perry) From Maluku, Sumatera, Sulawesi and Java With Metabolomic Based On GC-MS Method. Pharmacon, 11(2), 57–61.
Novita Setya H, Aprilia Budiarti, dan M. (2012). Proses Pengambilan Minyak Atsiri Dari Daun Nilam Dengan Pemanfaatan Gelombang Mikro (Microwave). Jurnal Teknik Pomits, 1(1), 1–5.
Nuraini, D. N. (2014). Aneka Manfaat Bunga untuk Kesehatan. Yogyakarta: Gava Media.
Nurdjannah, N., & N., B. (2012). Cloves (2nd ed.). Indonesian Agency for Agriculture Research and Development (IAARD).
Pauli, A. (2006). Anticandidal low molecular compounds from higher plants with special reference to compounds from essential oils. Medicinal Research Reviews, 26(2), 223–268. https://doi.org/10.1002/med.20050
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
Sari, N. M., Elsania, F., & Muyassaroh, M. (2020). Eugenol Dari Daun Cengkeh Menggunakan Metode Steam-Hydro Distillation Microwave Dengan Variasi Perlakuan Bahan Dan Daya Operasi. Jurnal Teknik Kimia, 14(2), 51–57. https://doi.org/10.33005/jurnal_tekkim.v14i2.2026
Kusumawati, A. H., Wulan, I. R., & Ridwanuloh, D. (2020). Formulation and physical evaluation sheet mask from red rice (Oryza Nivara) and virgin coconut oil (Cocos Nucifera L). International Journal of Health & Medical Sciences, 3(1), 60-64. https://doi.org/10.31295/ijhms.v3n1.148
Schmidt, E., Jirovetz, L., Wlcek, K., Buchbauer, G., Gochev, V., Girova, T., … Geissler, M. (2007). Antifungal Activity of Eugenol and Various Eugenol-Containing Essential Oils against 38 Clinical Isolates of Candida albicans. Journal of Essential Oil-Bearing Plants, 10(5), 421–429. https://doi.org/10.1080/0972060X.2007.10643575
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