Frequency of hirsutism in patients with PCOS (polycystic ovary syndrome)
Keywords:
polycystic ovarian syndrome, PCOS, hirsutism, hyperandrogenism, insulin resistance, obesity, oligo-ovulatory, infertilityAbstract
Objective: To estimate the prevalence of PCOS, a clinically noticeable disorder in women that causes excessive development of coarse or dark hair on the face, chest, and back in a male-like pattern, between first-degree female relatives in families with a proband who has the condition. Methods: A history of oligomenorrhea, hirsutism or biochemical proof of hyperandrogenism (raised entire or free T) and other illnesses were used to diagnose PCOS. Moreover, for better results, Study participants through PCOS (age 24.3G5.8 years, Body Mass Index 26.8G6.9 kg/m2) were used for better results. An R8-modified Ferriman-Gallwey score was used to characterize hirsutism. Results: 24% of the mothers and 32% of the sisters among the moms and sisters assessed had PCOS, respectively. Only premenopausal women who were not receiving treatment i.e., moms (35%) and sisters (40%) for PCOS were found to have the condition, which is consistent with symptoms becoming better due to hormone therapy or age. These PCOS prevalence percentages are much greater than the illness's frequency in the normal community (about 4%), which points to a considerable hereditary component. Furthermore, in comparison to female without hirsutism, hirsute female were pretty young, had greater BMIs, and also had greater amounts of circulatory androgens.
Downloads
References
Somani, N., Harrison, S., & Bergfeld, W. F. (2008). The clinical evaluation of hirsutism. Dermatologic therapy, 21(5), 376-391.
Toscani, M., Migliavacca, R., de Castro, J. A. S., & Spritzer, P. M. (2007). Estimation of truncal adiposity using waist circumference or the sum of trunk skinfolds: a pilot study for insulin resistance screening in hirsute patients with or without polycystic ovary syndrome. Metabolism, 56(7), 992-997.
McGovern, P. G., Legro, R. S., Myers, E. R., Barnhart, H. X., Carson, S. A., Diamond, M. P., ... & Giudice, L. C. (2007). Utility of screening for other causes of infertility in women with “known” polycystic ovary syndrome. Fertility and sterility, 87(2), 442-444.
Rapaport, F., Boisson, B., Gregor, A., Béziat, V., Boisson-Dupuis, S., Bustamante, J., ... & Patin, E. (2021). Negative selection on human genes underlying inborn errors depends on disease outcome and both the mode and mechanism of inheritance. Proceedings of the National Academy of Sciences, 118(3), e2001248118.
Franks, S., Webber, L. J., Goh, M., Valentine, A., White, D. M., Conway, G. S., ... & McCarthy, M. I. (2008). Ovarian morphology is a marker of heritable biochemical traits in sisters with polycystic ovaries. The Journal of Clinical Endocrinology & Metabolism, 93(9), 3396-3402.
Stuart, H. (2003). Violence and mental illness: an overview. World Psychiatry, 2(2), 121.
Dumesic, D. A., Oberfield, S. E., Stener-Victorin, E., Marshall, J. C., Laven, J. S., & Legro, R. S. (2015). Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocrine reviews, 36(5), 487-525.
Resta, R., Biesecker, B. B., Bennett, R. L., Blum, S., Estabrooks Hahn, S., Strecker, M. N., & Williams, J. L. (2006). A new definition of genetic counseling: National Society of Genetic Counselors’ task force report. Journal of genetic counseling, 15(2), 77-83.
Wolf, W. M., Wattick, R. A., Kinkade, O. N., & Olfert, M. D. (2018). Geographical prevalence of polycystic ovary syndrome as determined by region and race/ethnicity. International journal of environmental research and public health, 15(11), 2589.
Brady, C., Mousa, S. S., & Mousa, S. A. (2009). Polycystic ovary syndrome and its impact on women’s quality of life: More than just an endocrine disorder. Drug, healthcare and patient safety, 1, 9.
Diamanti-Kandarakis, E., Piperi, C., Argyrakopoulou, G., Spina, J., Papanastasiou, L., Bergiele, A., & Panidis, D. (2006). Polycystic ovary syndrome: the influence of environmental and genetic factors. HORMONES-ATHENS-, 5(1), 17.
Chen, W., Obermayer‐Pietsch, B., Hong, J. B., Melnik, B. C., Yamasaki, O., Dessinioti, C., ... & Zouboulis, C. C. (2011). Acne‐associated syndromes: models for better understanding of acne pathogenesis. Journal of the European Academy of Dermatology and Venereology, 25(6), 637-646.
Rutter, M., Dunn, J., Plomin, R., Simonoff, E., Pickles, A., Maughan, B., ... & Eaves, L. (1997). Integrating nature and nurture: Implications of person–environment correlations and interactions for developmental psychopathology. Development and psychopathology, 9(2), 335-364.
McDonald, J., Jayasuriya, R., & Harris, M. F. (2012). The influence of power dynamics and trust on multidisciplinary collaboration: a qualitative case study of type 2 diabetes mellitus. BMC Health Services Research, 12(1), 1-10.
Hsu, M. I. (2013). Changes in the PCOS phenotype with age. Steroids, 78(8), 761-766.
Panidis, D., Tziomalos, K., Papadakis, E., Chatzis, P., Kandaraki, E. A., Tsourdi, E. A., ... & Katsikis, I. (2013). The clinical significance and primary determinants of hirsutism in patients with polycystic ovary syndrome. Eur J Endocrinol, 168(6), 871-877.
Published
How to Cite
Issue
Section
Copyright (c) 2023 International journal of health sciences
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.