Clinical, laboratory and instrumental indicators in patients who have undergone COVID-19

Muso Urinov; Nigora Alikulova; Dilfuza Zukhritdinova; Mekhriddin Usmonov; Rakhimjon Urinov

doi:10.53730/ijhs.v5n3.1719

Authors

Muso Urinov
urinov@gmail.ru
Bukhara Medical Institute, Ministry of Health of the Republic of Uzbekistan, Bukhara, Uzbekistan
Nigora Alikulova Center for Qualification of Professional Development of Medical Workers, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan
Dilfuza Zukhritdinova Center for Qualification of Professional Development of Medical Workers, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan
Mekhriddin Usmonov Gijduvan District Hospital of Bukhara region, Bukhara, Uzbekistan
Rakhimjon Urinov Bukhara State Medical Institute, Bukhara, Uzbekistan

Keywords:

comorbid, complication, coronavirus infection, COVID-19, individual healthy, neurology, patient treatment

Abstract

280 patients with COVID-19 were examined (average age 53.9±8.1 years; gender index 1.37:1.0 (162 men and 118 women). It was revealed that young people (especially women) were more common with a mild course of the disease (64.2%), middle – aged people-with a moderate-severe variant of COVID-19 (54.8%), In the group of patients with a severe course of coronavirus infection, female patients prevailed among the elderly, and among middle –aged men – 47.8% and 48.4%, respectively. The comorbid background before the disease CAVID-19 and the neurological complications that appeared on the background of CAVID-19 in the percentage ratio prevailed in males. There were no significant differences in the frequency of complications from the severity of the COVID-19 disease. It was revealed that at the time of hospitalization, all the studied markers of coagulation activity were changed and statistically significantly differed from the reference interval, which indicated the activation of the procoagulation potential. In the group of female patients, these indicators were more pronounced. CT examination revealed that the percentage of damage to both lungs was significantly higher in female patients compared to male patients.

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References

Attamimi, H. R. ., Lestari, Y. ., Situmorang, B. . H. L. ., Antari, G. Y. ., & Nugrawati, N. . (2020). Application of habituation method in germas interventionsin: the pandemic time COVID-19 . International Journal of Health & Medical Sciences, 3(1), 98-104.

Bazdyrev, E.D. (2020.) Coronavirus infection - an urgent problem of the XXI century. Complex problems of cardiovascular diseases. 9(2), 6-16.

Belyakov, N.A., Rassokhin V.V., & Yastrebova E.B. (2020). Coronavirus infection COVID-19 the nature of the virus, pathogenesis, clinical manifestations. message 1. HIV infection and immunosuppression. 12.(1), 7-2.

Bruno, V. D., & Batchelor, T. J. (2009). Late aortic injury: a rare complication of a posterior rib fracture. The Annals of thoracic surgery, 87(1), 301-303. https://doi.org/10.1016/j.athoracsur.2008.05.075

Cully, J. A., Graham, D. P., Stanley, M. A., Ferguson, C. J., Sharafkhaneh, A., Souchek, J., & Kunik, M. E. (2006). Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression. Psychosomatics, 47(4), 312-319. https://doi.org/10.1176/appi.psy.47.4.312

He, Z., Zhao, C., Dong, Q., Zhuang, H., Song, S., Peng, G., & Dwyer, D. E. (2005). Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets. International journal of infectious diseases, 9(6), 323-330. https://doi.org/10.1016/j.ijid.2004.07.014

Hussin, D. A., Samah, M. A. A., Suhaimi, A. A., & Kamarudin, M. K. A. (2021). A study on knowledge, attitude and practice of COVID-19 pandemic among the residents. International Journal of Health Sciences, 5(2), 177-188.

Kim, S. W., & Su, K. P. (2020). Using psychoneuroimmunity against COVID-19. Brain, behavior, and immunity, 87, 4-5. https://doi.org/10.1016/j.bbi.2020.03.025

Loeber, R., & Keenan, K. (1994). Interaction between conduct disorder and its comorbid conditions: Effects of age and gender. Clinical psychology review, 14(6), 497-523. https://doi.org/10.1016/0272-7358(94)90015-9

Mahardika, I. M. R., Suyasa, I. G. P. D., Kamaryati, N. P., & Wulandari, S. K. (2021). Health literacy is strongest determinant on self-monitoring blood glucose (SMBG) type 2 DM patients during COVID-19 pandemic at public health centre in Tabanan Regency. International Journal of Health & Medical Sciences, 4(3), 288-297.

Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., Manson, J. J., & Collaboration, H. L. H. Across Speciality (2020). COVID?19: Consider cytokine storm syndromes and immunosuppression. The Lancet (London, England), 395(10229), 1033.

Meng, T., Cao, H., Zhang, H., Kang, Z., Xu, D., Gong, H., ... & Liu, J. (2020). The insert sequence in SARS-CoV-2 enhances spike protein cleavage by TMPRSS. BioRxiv.

Ningsih, S., Ismail, D., & Indriani, I. (2021). Study protocol: relationship between parenting patterns and diet with nutritional status of toddlers during COVID-19 pandemic. International Journal of Health Sciences, 5(2), 128-134.

Nixon, R. D., Resick, P. A., & Nishith, P. (2004). An exploration of comorbid depression among female victims of intimate partner violence with posttraumatic stress disorder. Journal of affective disorders, 82(2), 315-320. https://doi.org/10.1016/j.jad.2004.01.008

Omrani, A. S., Saad, M. M., Baig, K., Bahloul, A., Abdul-Matin, M., Alaidaroos, A. Y., ... & Albarrak, A. M. (2014). Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study. The Lancet Infectious Diseases, 14(11), 1090-1095. https://doi.org/10.1016/S1473-3099(14)70920-X

Polushkin, M.A., Sitdikov G.A., & Tolmachev D.A. (2020). Assessment of the mental state of medical students during self-isolation due to the COVID-19 pandemic. Modern Science. 12(2), 188-192.

Sonmez, B., Demirsoy, E., Yagan, N., Unal, M., Arbatli, H., Sener, D., ... & Ilkova, F. (2003). A fatal complication due to radiofrequency ablation for atrial fibrillation: atrio-esophageal fistula. The Annals of thoracic surgery, 76(1), 281-283. https://doi.org/10.1016/S0003-4975(03)00006-7

Tang, N. D., Li, X., Wang, & Z. Sun. (2020). Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J. Thromb. Haemost. 18(4), 844–847.

Tepanyan, S.A. (2020). The impact of the COVID-19 pandemic on the psychological state of the population. Scientific and practical research. 12-2(35), 63-70.

Ter Meulen, J., Bakker, A. B., Van Den Brink, E. N., Weverling, G. J., Martina, B. E., Haagmans, B. L., ... & Osterhaus, A. D. (2004). Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets. The Lancet, 363(9427), 2139-2141. https://doi.org/10.1016/S0140-6736(04)16506-9

Tetro, J. A. (2020). Is COVID-19 receiving ADE from other coronaviruses?. Microbes and infection, 22(2), 72-73. https://doi.org/10.1016/j.micinf.2020.02.006

WHO (2020). Clinical guidelines for the management of patients with severe acute respiratory infection suspected of being infected with a novel coronavirus (2019-nCoV).

Widana, I.K., Sumetri, N.W., Sutapa, I.K., Suryasa W. (2020). Anthropometric measures for better cardiovascular and musculoskeletal health. Comput Appl Eng Educ, 1–12. https://doi.org/10.1002/cae.22202

Winkler, P., Formanek, T., Mlada, K., Kagstrom, A., Mohrova, Z., Mohr, P., & Csemy, L. (2020). Increase in prevalence of current mental disorders in the context of COVID-19: analysis of repeated nationwide cross-sectional surveys. Epidemiology and psychiatric sciences, 29.

Yang, Y., Peng, F., Wang, R., Guan, K., Jiang, T., Xu, G., ... & Chang, C. The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China, 5 2020. J. Autoimmun, 102434.

Zulfa, S. Z., Emilia, O., & Hidayat, A. (2021). Midwives preparation to provide delivery services in independent midwife practice during COVID-19 pandemic. International Journal of Health Sciences, 5(3), 344-351.