SARS-CoV-2 detection using real-time RT-PCR and the relationship between immunological markers Interleukin -4, Interleukin -6 and SARS-CoV-2 patient groups
Keywords:S gene, E gene, N gene, Interleukin-4, Interleukin-6, SARS-CoV-2
Abstract: Coronaviruses (CoVs) refer to one of the RNA virus infections can showed as one of diseases virus effect of humans. They're wrapped infections with massive single-strand positive sense RNA genomes that can infect humans, animals, birds, bats, mice, and a number of other wild creatures' respiratory, gastrointestinal, hepatic, and focused sensory systems. Material and Method: viral 90 patients, a nasopharyngeal swab can be focused on a lot. COVID-19 and non-COVID-19 serum patients cytokines were identified by ELISA, while SARS-CoV-2 IL-4and, IL-6 were recognized by chemiluminescence method. Results: S quality is generally present in the early stages of contamination, with only a few extended stretches of contamination, whereas E quality is present in the late stages of disease, north of 1 - several weeks after the start of contamination, as well as N quality to a lesser extent. With 90% amino corrosive homology and less modifications over time, the N quality is more regulated and stable. The (S and/E quality) heterozygote has a higher rate than the others.
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