Troponin_I as a predictor of outcome in pediatric postoperative cardiac surgeries

Rasha Ibrahim Aly Ammar; Wael Ahmed Attia; Amal Rizk; Khaled Sami Mahmoud Gad Elhessi; Mohammed Mosaad Mahmoud

doi:10.53730/ijhs.v6nS8.11873

Authors

Rasha Ibrahim Aly Ammar Pediatrics department, Faculty of Medicine, Cairo University, Egypt
Wael Ahmed Attia Pediatrics department, Faculty of Medicine, Cairo University, Egypt
Amal Rizk Clinical Pathology department, Faculty of Medicine, Cairo University, Egypt
Khaled Sami Mahmoud Gad Elhessi
Khaled_elhessy@yahoo.com
Pediatric Cardiology department, Al-Nas hospital, Cairo, Egypt
Mohammed Mosaad Mahmoud Pediatrics department, Faculty of Medicine, Cairo University, Egypt

Keywords:

troponin-I (TN-I), cardiac surgery, predictor, outcome, cardiopulmonary bypass surgery

Abstract

Background: Troponin-I (TN-I) levels are elevated following pediatric cardiac surgery with speculation that particular patterns may have prognostic significance. There is lack of procedure-specific data regarding postoperative TN-I levels in infants undergoing cardiac surgery. Aim and objectives: the aim of the study was to assess the usefulness of routine monitoring of cardiac troponin I concentrations within 24 hours of surgery (cTn-I<24h) in neonates and infants undergoing cardiopulmonary bypass surgery. Also, correlate troponin I with postoperative mortality and morbidity in patients between one day and 15 years old who underwent cardiac surgery for congenital heart disease. Subjects and methods: This was a prospective randomized study in the period from April 2019 to November 2021, was conducted on 103 pediatric patients from Pediatric cardiac intensive care units in Abu El-Rish children's Hospital and Al-Nas hospital aging from one day old to 15 years old and had cardiopulmonary bypass surgery. Blood samples for troponin levels were taken from all patients in ICU on admission and 24 hours after operation.

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