Liver assessment post laparoscopic mini gastric bypass versus sleeve gastrectomy operation in obese and morbidly obese patients

https://doi.org/10.53730/ijhs.v6nS1.6806

Authors

  • Mohammed Abo Mira General Surgery department, Faculty of Medicine, Al-Azhar University, Egypt
  • Nagah Mohamed Salem General Surgery department, Faculty of Medicine, Al-Azhar University, Egypt
  • Ahmed Hamdy General surgery at (NHTMRI) national hepatology & tropical medicine research institute
  • Mohammed Hashem Attia Specialist of General Surgery Nasser Institute

Keywords:

Liver, laparoscopic Mini Gastric Bypass, Sleeve Gastrectomy Morbid Obesity

Abstract

Background: Morbid obesity is a severe disorder associated with major co‐morbidities reduced quality of life (QoL) and reduced life expectancy. Aim and objectives: The purpose of the study was to compare the effect of laparoscopic mini gastric bypass versus sleeve operation on liver function in a prospective randomized study. Subjects and methods: This study was a prospective study conducted on 80 patients who visit the general surgery clinic at Damietta university hospital (Al Azhar University) and National hepatology and tropical medicine research institute (NHTMRI); patients were being divided into 2 groups: Group A (40 patients): Undergoing laparoscopic sleeve gastrectomy surgery. Group B (40 patients):  undergoing laparoscopic mini gastric bypass surgery. Results: There a gradual significant decrease from preoperative to 12 months postoperative regarding ALT and AST in Group A, while there a gradual significant decrease from preoperative to 12 months postoperative regarding AST in Group B, Conclusion: This study demonstrated a low prevalence of abnormal LFT in our morbidly obese patients who underwent bariatric surgery. This may serve as an indirect indication of a lower prevalence of significant liver damage in these subjects.

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References

Ignat M, Vix M, Imad I, D'Urso A, Perretta S, Marescaux J. Mutter; British Journal of Surgery. 2017; 104(3):248–256.

Flegal KM, Kit BK, Orpana H. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013; 309(1):71–82

Sundbom M. Laparoscopic revolution in bariatric surgery. World J Gastroenterol. 2014; 20(41): 15135–43.

Torgersen Z, Osmolak A, Forse RA. Sleeve gastrectomy and Roux En Y gastric bypass: current state of metabolic surgery. CurrOpinEndocrinol Diabetes Obes. 2014; 21(5): 352–357. doi: 10.1097/MED.0000000000000099

Guillaume L, Robert C, David B, Marie P, Hélène V, Julien L, et al. Gastroenterology, 2015.

Magdalena E, Felix B, Kathae in a Staufer Obes surg. 2018; 28(3): 812-819

Wijetunga U, Bulugahapitiya U, Wijeratne T. SAT-111 Reversal of Nonalcoholic Fatty Liver Disease with Bariatric Surgery in South Asians: Does the Type of Surgery Matter?. J Endocr Soc. 2019; 3(Suppl 1): SAT-111. Published 2019 Apr 30. doi:10.1210/js.2019-SAT-111

Xourafas D, Ardestani A, Ashley SW, Tavakkoli A. Impact of weight-loss surgery and diabetes status on serum ALT levels. Obes Surg 2012; 22:1540–7.

Talha A, Abdelbaki T, Farouk A. Cholelithiasis after bariatric surgery, incidence, and prophylaxis: randomized controlled trial. Surg Endosc, 2020; 34: 5331–5337. https://doi.org/10.1007/s00464-019-07323-7

Khalil O, Mansy H and Abdalla WS. Laparoscopic sleeve gastrectomy with loop bipartition versus laparoscopic sleeve gastrectomy in treating obese people with type II diabetes mellitus: a prospective randomized comparative study. The Egyptian Journal of Surgery, 2019; 38(3); 610-9.

Ruiz-Tovar, J, Alsina, M. E, Alpera, M. R, & OBELCHE Group. Improvement of nonalcoholic fatty liver disease in morbidly obese patients after sleeve gastrectomy: association of ultrasonographic findings with lipid profile and liver enzymes. Acta Chirurgica Belgica, 2017; 117(6), 363-369.

Aksoy, E. K, Göktaş, Z, Albuz, Ö, Akpınar, M. Y, Öztürk, D, Buluş, H, & Uzman, M. Effects of sleeve gastrectomy on liver enzymes, non-alcoholic fatty liver disease-related fibrosis and steatosis scores in morbidly obese patients: first year follow-up. Journal of Laboratory Medicine, 2019; 43(2), 115-122.

Nickel F, Tapking C, Benner L, Sollors J, Billeter AT, Kenngott HG, et al. Bariatric surgery as an efficient treatment for on-alcoholic fatty liver disease in a prospective study with 1-year follow-up: BariScan Study. Obes Surg 2018; 28:1342–50.

Noun R, Skaff J and Riachi E. One thousand consecutive mini-gastric bypass: short-and long-term outcome. Obesity Surgery, 2012; 22(5): 697-703.

Mohamed D, Abd-Elal Nafh M, Mohamed A. Comparative study of outcomes between laparoscopic single anastomosis sleeve ileum bypass (sasi bypass) versus laparoscopic mini-gastric bypass in morbid obese patients. Al-azhar medical journal, 2020; 49(3): 957-970.

Lee WJ, Almulaifi A, Tsou JJ. Laparoscopic sleeve gastrectomy for type 2 diabetes mellitus: predicting the success by ABCD score. Surg Obes Relat Dis, 2015; 11:991-6.

Musella M, Susa A, Greco F. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surgical Endoscopy, 2014; 28(1): 156-163.

Published

30-04-2022

How to Cite

Mira, M. A. ., Salem, N. M., Hamdy, A., & Hashem Attia, M. (2022). Liver assessment post laparoscopic mini gastric bypass versus sleeve gastrectomy operation in obese and morbidly obese patients. International Journal of Health Sciences, 6(S1), 9451–9461. https://doi.org/10.53730/ijhs.v6nS1.6806

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Section

Peer Review Articles