Correlation of spleen stiffness measured by Acoustic Radiation Force Impulse Imaging (ARFI) with Hepatic Venous Pressure Gradient (HVPG) in the prediction of esophageal varices (EVs) grades in cirrhotic patients

Maged Elghannam; Ahmed Khairy; Ali Abdel Rahim; Mohammed Ragab; Mohamed Hosni K. Abdelmaksoud; Mohamed F. H Abdallah; Abdulkarim Ahmed Alsayyad; Naglaa Zayed; Ayman Yosry

doi:10.53730/ijhs.v6nS6.9156

Authors

Maged Elghannam Hepato-gastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt
Ahmed Khairy Endemic Medicine Department, Faculty of Medicine, Cairo University, Egypt
Ali Abdel Rahim
ali_tbri_1982@yahoo.com
Hepato-gastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt
Mohammed Ragab Hepato-gastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt
Mohamed Hosni K. Abdelmaksoud Radiology Department, Theodor Bilharz Research Institute, Giza, Egypt
Mohamed F. H Abdallah Radiology Department, Theodor Bilharz Research Institute, Giza, Egypt
Abdulkarim Ahmed Alsayyad Endemic Medicine Department, Faculty of Medicine, Cairo University, Egypt
Naglaa Zayed Endemic Medicine Department, Faculty of Medicine, Cairo University, Egypt
Ayman Yosry Endemic Medicine Department, Faculty of Medicine, Cairo University, Egypt

Keywords:

Spleen stiffness, ARFI, liver cirrhosis, HPVG, Esophageal varices

Abstract

Background: measurement of spleen stiffness (SS) by ARFI may predict the presence of EVs. Aim: To assess the correlation of SS measured by ARFI as noninvasive assessment with HVPG in the prediction of presence and grades of EVs in cirrhotic patients. Methods: 30 patients with post HCV liver cirrhosis who underwent biochemical tests, abdominal ultrasound (US) , Doppler , Upper gastrointestinal endoscopy (UGE), liver stiffness (LS) and spleen stiffness (SS) measurements using ARFI elastography and HVPG. Results: statistically significant difference was found between EVs presence and grades in relation to HVPG. In contrary no statistically significant difference was found between EVs presence and grades in relation to SS. Conclusion: HVPG had good significant positive correlation with presence and grades of EVs. There was no significant correlation between non-invasive parameters including the SS and LS (by ARFI) and presence or grades of EVs. There was no significant correlation between HVPG and SS and LS (by ARFI).

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