A study on the efficacy of Staphyloccus aureus biofilm formation in atopic dermatitis severity
Keywords:
atopic dermatitis, staphylococcus aureus, biofilmsAbstract
The chronic, recurrent, inflammatory skin condition known as atopic dermatitis (AD) is a significant contributor to the global burden of disease in terms of public health. Staphylococcus aureus and Staphylococcus epidermidis are two types of bacteria that frequently inhabit AD lesions. Recent research has shown that clinical isolates of Staphylococcus spp. that colonise AD skin are frequently biofilm-positive. The tendency of Staphylococcus spp. to form biofilms, which are colonies that attach themselves to surfaces and become highly resistant to antibiotics and immune responses, is an important characteristic of this genus of bacteria. The production of biofilms leads to the development of intricate bacterial communities, each of which has its own distinct impact on the keratinocytes and the immune system of the host. In this paper, we investigate the function that staphylococcal biofilms play in atopic dermatitis as well as the implications for treatment.
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