Comparison of serum troponin level and echocardiographic parameters between male and femal patients with ACS
Keywords:
Acute Coronary Syndromes, sex, hs-cTnAbstract
Background: Acute Coronary Syndrome is one of the commonly diagnosed life threatening condition as of now. Hence it is necessary to diagnose early and assess the severity of disease as soon as possible. Troponin is considered a specific marker for the diagnosis of acute coronary syndrome (ACS). Aim: To estimate the high-sensitivity cardiac troponin (hs-cTn) in Acute coronary syndrome patients. Also to compare serum troponin levels and echocardiographic parameter in patient's gender. Materials and Methods: 70 patients of both sexes who got admitted within 24 hours after onset of symptoms and diagnosed as Acute Coronary Syndrome in Hospital of Baghdad /medical city during the period of December 2020 to December 2021. The (hs-cTn) was measure in the blood with Elisa Assay kit. Results: This study included 70 patients, they divided into two groups: Male group and female group. The control group included 20 healthy persons. There was a significant increase in the frequency of ACS among males in comparison to females (P-value =0.0027). The mean (± SEM) value of serum hs-troponin I concentrations did not differ significantly (p=0.372) as compared with mean (± SEM) value of serum control group.
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References
1-Harrison Principles of internal medicine 19th edition, chapter 249
Thygesen K, Alpert JS, Jeffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. J Am Coll Cardiol 2012;60:1581-98.
Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Eur Heart J. 2012;33:2551–2567. Røysland R, Kravdal G, Høiseth AD, et al. Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study. Clin Sci (Lond) 2012;122:599–606. doi: 10.1093/eurheartj/ehs184.
Thygesen K, Mair J, Giannitsis E, et al. How to use high-sensitivity cardiac troponins in acute cardiac care. Eur Heart J. 2012;33:2252–2257. doi: 10.1093/eurheartj/ehs154.
Logeart D, Beyne P, Cusson C, et al. Evidence of cardiac myolysis in severe nonischemic heart failure and the potential role of increased wall strain. Am Heart J. 2001;141:247–253. doi: 10.1067/mhj.2001.111767.
Thygesen K, Alpert JS, White HD, on behalf of the Joint ESC/ACCF/AHA/WHF: Task Force for the Redefinition of Myocardial Infarction. Universal definition of myocardial infarction. Eur Heart J 2007; 28:2525–38.
Wong GC, Morrow DA, Murphy S, et al : for the TACTICS-TIMI 18 Study Group. Elevations in troponin T and I are associated with abnormal tissue level perfusion: aTACTICS-TIMI 18 substudy. Treat Angina with Aggrastat and Determine Cost of Therapy with an Invasive or Conservative Strategy—Thrombolysis in Myocardial Infarction. Circulation 2002;106:202–7.
Morrow DA, Cannon CP, Jesse RL, et al : National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Clin Chem 2007;53:552–74.
Fred S. Apple, Stephen W. Smith,Lesly A. Pearce, and MaryAnn M. Murakami. : Assessment of the Multiple-Biomarker Approach for Diagnosis of Myocardial Infarction in Patients Presenting with Symptoms Suggestive of Acute Coronary Syndrome. Clinical Chemistry.2009; 55:193–100.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
Villar IC, Hobbs AJ and Ahluwalia A. : Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. Journal of Endocrinology 2008; 197: 447-462.
Antari, N. W. S. ., Damayanti, I. A. M. ., & Wulansari, N. T. . (2021). The effectiveness testing of l-carnitine on the quality of spermatozoa and testosterone hormone in white rats (Rattus norvegicus) feeding with high fat. International Journal of Health & Medical Sciences, 4(1), 102-109. https://doi.org/10.21744/ijhms.v4n1.1525
Shah ASV, Griffiths M, Lee KK, et al. High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study. BMJ. 2015;350:g7873. doi: 10.1136/bmj.g7873.
Kuan Ken Lee etal. Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome. J Am Coll Cardiol. 2019 Oct 22; 74(16): 2032–2043
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