Diagnostic accuracy of contrast and non-contrast 1.5 tesla magnetic resonance imaging for lumbar herniated nucleus pulposus based on surgical findings: A systematic review and meta-analysis of diagnostic test accuracy studies

Endra Wibisono Harmawan; Tedy Apriawan; Eko Agus Subagio; Muhammad Faris; Sri Andreani Utomo; Budi Utomo; Abdul Hafid Bajamal

doi:10.53730/ijhs.v6nS6.10200

Authors

Endra Wibisono Harmawan Neurosurgeon. Department of Neurosurgery. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Tedy Apriawan
drtedyapri@fk.unair.ac.id
Neurosurgeon Staff. Department of Neurosurgery. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Eko Agus Subagio Spine Neurosurgeon Staff. Department of Neurosurgery. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Muhammad Faris Spine Neurosurgeon Staff. Department of Neurosurgery. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Sri Andreani Utomo Neuroradiologist Staff. Department of Radiology. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Budi Utomo Statistics lecturer. Department of Public Health and Preventive Medicine. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Abdul Hafid Bajamal Prof of Neurosurgeon. Department of Neurosurgery. Faculty of Medicine, Airlangga University- Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

Keywords:

diagnostic test accuracy, MRI, herniated nucleus pulposus, surgical findings

Abstract

This study aims to provide the latest information regarding the accuracy of contrast and non-contrast 1.5 Tesla MRI in the diagnosis of lumbar Herniated Nucleus Pulposus (HNP) compared with surgical findings. We included studies with subjects diagnosed with lumbar HNP due to degenerative processes, preoperative 1.5 Tesla contrast, and non-contrast MRI and described the number of findings of MRI diagnostic tests (index test) on the actual conditions found during surgery (reference standard). We searched literature from 5 databases: ProQuest, Pubmed, Cochrane Library, Biomed Central, and ScienceDirect. The sensitivity and specificity of contrast and non-contrast 1.5 Tesla MRI ranged between 64-95% and 55-100% (95% CI) with the area under the curve above the threshold on the ROC curve. Two studies compared the accuracy of MRI and Computed Tomography (CT) myelography with a wider ROC curve on CT myelography than on MRI. The ROC curve which has a wide area under the curve above the threshold depicts the relationship between sensitivity and specificity, shows that contrast non-contrast 1.5 Tesla MRI has a good accuracy in HNP diagnostic.

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