Formulation and evaluation of nitric oxide nasal spray
Keywords:
formulation, evaluation, nitric oxide, nasal sprayAbstract
Many studies have found that anti-covid nasal sprays and gargles are more effective at preventing SARSCOV-2 infection. Antiviral qualities are seen in anti-covid nasal sprays and gargles. "Invisi Mask, Nitric oxide Nasal spray (NONS), Povidone-iodine Nasal spray (PVP-I), Taffix spray" are some of the most regularly used anti-covid nasal sprays. "Povidone-iodine gargle (PVP-I), Betadine gargle, 'Nozin,' Chlorhexidine gargle, hydrogen-peroxide gargle, dequonal, dequalinium chloride, and Benzalkonium chloride independently with antiviral and virus, Cetylpyridinium chloride, C31 G," We also found that pre-treating cells with the product prevented SARS-CoV-2 infection, regardless of viral subtype. The creation of a physical, passive barrier appears to be the major mechanism of action. In other combinations, however, the addition of wild garlic gave extra direct antiviral activities. We suggest that nasal sprays based on HPMCs could be a useful supplement to efforts for limiting the transmission of respiratory viruses, such as SARS-CoV-2.
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