Periodontium in pregnancy
A systematic review
Keywords:
periodontitis, pregnancy, maternal morbidity, mortalityAbstract
Introduction: Periodontal diseases are advocated to show adverse pregnancy outcomes. Hence in our study we aim to conduct a systematic review of the previous systemic reviews studying the association between periodontal disease and adverse pregnancy outcomes. Material and methods: We searched online databases up to November 2016 for the previous Systematic reviews of studies comparing pregnancy outcomes among women with and without periodontal disease were eligible for inclusion. Primary outcomes were maternal mortality, preterm birth, and perinatal mortality. Results: From the 23 none reported the association between periodontal disease and maternal or perinatal mortality. Systematic reviews with the lowest risk of bias consistently demonstrated positive associations between periodontal disease and preterm birth, low birth weight, preeclampsia, and preterm LBW. Based on these figures, estimated population- attributable fractions for periodontal disease were 5% to 38% for preterm birth, 6% to 41% for LBW, and 10%to 55% for preeclampsia. Due to substantial overlap in included primary studies, we could not combine results across reviews. Conclusion: We can conclude that pregnant women with periodontal disease are at increased risk of developing preeclampsia and delivering a preterm and/or LBW baby.
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Aagaard K, Ma J, Antony KM, Ganu R, Petrosino J, Versalovic J. 2014. The placenta harborsa unique microbiome. Sci Transl Med. 6(237):237-65.
American College of Obstetricians and Gynecologists Women’s Health Care Physicians, Committee on Health Care for Underserved Women. 2013. Committee opinion No. 569: oral health care during pregnancy and through the lifespan. Obstet Gynecol. 122(2 Pt 1):417–22.
Chaparro A, Blanlot C, Ramirez V, Sanz A, Quintero A, Inostroza C, Bittner M, Navarro M, Illanes SE. 2013. Porphyromonas gingivalis, Treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: a case-control study. J Periodontal Res. 48(6):802–809.
Cochrane Effective Practice and Organisation of Care. 2002. Data collection checklist. Ottawa: Institute of Population Health, University of Ottawa;
GBD 2013 Mortality and Causes of Death Collaborators. 2015. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 385(9963):117–171.
Jarjoura K, Devine PC, Perez-Delboy A, Herrera- Abreu M, D’Alton M, Papapanou PN.2005. Markers of periodontal infection and preterm birth. Am J Obstet Gynecol. 192(2):513–519.
Kunnen A, Blaauw J, van Doormaal JJ, van Pampus MG, van der Schans CP, Aarnoudse JG, van Winkelhoff AJ, Abbas F. 2007.Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition. J Clin Periodontol. 34(3):202–207.
Lin D, Smith MA, Elter J, Champagne C, Downey CL, Beck J, Offenbacher S. 2003. Porphyromonas gingivalis infection in pregnant mice is associated with placental dissemination, an increase in the placental Th1/Th2 cytokine ratio, and fetal growth restriction. Infect Immun. 71(9):5163–5168.
Liu H, Redline RW, Han YW. 2007.Fusobacterium nucleatum induces fetal death in mice via stimulation of TLR4- mediated placental inflammatory response. J Immunol. 179(4):2501–2508.
Michigan Department of Health and Human Services. 2016. During pregnancy, the mouth matters: a guide to Michigan perinatal oral health. Ypsilanti (MI): Michigan Department of Health and Human Services; [accessed 2017 Aug 22]. http://www.michigan.gov/documents/mdhhs/Oral_Health_ Guidelines_2015_508090_7.pdf
Muthoharoh, B. L., Kartini, F., & Fitriahadi, E. (2022). Pregnant women’s perceptions of anemia and iron supplement consumption. International Journal of Health & Medical Sciences, 5(2), 183-192. https://doi.org/10.21744/ijhms.v5n2.1902
Offenbacher S, Beck JD, Jared HL, Mauriello SM, Mendoza LC, Couper DJ, Stewart DD, Murtha AP, Cochran DL, Dudley DJ, et al; Maternal Oral Therapy to Reduce Obstetric Risk (MOTOR) Investigators. 2009. Effects of periodontal therapy on rate of preterm delivery: a randomized controlled trial.Obstet Gynecol. 114(3):551–559.
Offenbacher S, Boggess KA, Murtha AP, Jared HL, Lieff S, McKaig RG, Mauriello SM, Moss KL, Beck JD. 2006. Progressive periodontal disease and risk of very preterm delivery. Obstet Gynecol. 107(1):29–36.
Oral Health Care During Pregnancy Expert Workgroup. 2012. Oral health care during pregnancy: a national consensus statement. Washington (DC): National Maternal and Child Oral Health Resource Center; https://www.mchoralhealth. org/ PDFs/OralHealthPregnancyConsensus.pdf.
Pihlstrom BL, Michalowicz BS, Johnson NW. 2005. Periodontal diseases. Lancet. 366(9499):1809–1820.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864
Vanterpool SF, Tomsin K, Reyes L, Zimmermann LJ, Kramer BW, Been JV. 2016. Risk of adverse pregnancy outcomes in women with periodontal disease and the effectiveness of interventions in decreasing this risk: protocol for systematic overview of systematic reviews. Syst Rev. 5:16.
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