Giant cell Granuloma
Histological comparison and a review
Keywords:
central giant cell granuloma, peripheral giant cell granulomaAbstract
Central giant cell granulomas (CGCG) constitute about 10% of benign jawbone lesions. Approximately one-third of CGCG exhibit local aggressive behavior with bone destruction and a tendency to recur.1 Jaffe (1953) was the first to distinguish central giant cell granulomas (CGCG) of the jawbones from other giant cell lesions of bones and originally called them“central giant cell reparative granulomas” since they were believed to be a reactive-reparative process that might heal spontaneously.1 Recently the World Health Organization has defined it as localized benign but sometimes aggressive osteolytic proliferation consisting of fibrous tissue with hemorrhage and haemosiderin deposits, presence of osteoclast-like giant cells and reactive bone formation. Many authors have established the differences with other lesions of giant cells. The clinical behavior of CGCG varies from a slowly asymptomatic swelling to an aggressive lesion that manifests with pain, cortical perforation, and root resorption.2 On the other hand the peripheral giant cell granuloma is a reactive exophytic lesion of the gingiva and alveolar ridge that usually occurs as a result of local irritating factors such as plaque, calculus, chronic infection, chronic irritation, tooth extraction, inproperly finished filling, unstable dental prosthesis, and impacted food which originates from the periosteium or periodontal ligament.
Downloads
References
Central giant cell granuloma of the jawbones – new insights into molecular biology with clinical implications on treatment approaches.Histol Histopathol (2008) 23: 1151-1160
Central giant cell granuloma of the mandibular condyle. Case-report. Rev. Clin. Periodoncia Implantol. Rehabil. Oral Vol. 6(2); 83-86, 2013
Giant Cell Granuloma Of The Maxilla. J Ayub Med Coll Abbottabad 2007; 19(3)
Giant Cell Lesion of the Jaw: A Case Report in a Child. People’s Journal of Scientific Research Vol. 4(1), Jan. 2011
Kardina, I., Ramadany, S., Sanusi B, Y., Made, S., Stang, S., & Syarif, S. (2020). Children’s midwifery learning media application about android-based rough motor development in improving midwifery student skills. International Journal of Health & Medical Sciences, 3(1), 146-152. https://doi.org/10.31295/ijhms.v3n1.300
Management of an unusual peripheral giant cell granuloma. A diagnostic dilemma. Contemporary Clinical dentistry Jan-Mar 2012, vol-3, issue 1. Page 93-96.
Peripheral Giant Cell Granuloma- A Review Indian Journal Of Multidisciplinary Dentistry, Vol. 2, Issue 2, February-April 2012
Peripheral Giant Cell Granuloma: A Case Report and Review of Literature. People’s Journal of Scientific Research Vol. 6(2), July 2013
R. Rajendran, B Sivapathsundharam Shafer’s Textbook of oral pathology 6th edition.
Recurrent central giant cell granuloma in the mandible: Surgical treatment and dental implant restoration.Med Oral Patol Oral Cir Bucal 2007;12:E229-32.
Surgical treatment and reconstruction of central giant cell granuloma (CGCG) of the of the aggressive type - case report and literature review Pol Otorhino Rev 2019: 8(4): 30-37
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.