The effect of body mass index and glycated hemoglobin levels on oxygen saturation in Type 2 diabetics
Keywords:
Obesity, Body mass index, HbA1c, oxygen saturation, Type 2 diabetes, hypoxia-inducible factorsAbstract
A high Body mass index (BMI) has multi-organ effects and influences cardiovascular and respiratory function in several direct and indirect ways. The present study examined the effect of obesity and HbA1c levels on oxygen saturation (SpO2) in Type 2 diabetics. 102 subjects (82 F, 20 M), all with confirmed diabetes, were included in the study. Their body-mass indices (BMI’s) were calculated from obtained anthropometric data on height and weight. HbA1c (%) was estimated using a latex agglutination inhibition assay and SpO2 (%) levels measured using pulse oximeter provided by the EDAN elite V6 series patient monitor. Boxplots displaying the five number summary were used in descriptive statistics. Pearson correlation and student’s T-test were used for statistical analysis. BMI showed a highly significant negative correlation with SpO2 (r = -0.47; p < 0.00001). BMI was positively correlated with age (r=0.22; p =0.028). However, no correlations were found between HbA1c on the one hand, and age, BMI and SpO2 on the other. Conclusions: HbA1c levels appear to be unaffected by age, BMI, SPO2. Variations of values between males and females about HbA1c and SpO2 are also insignificant.
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