Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary diseaseon general respiratory wards: A prospective study

Dileep Kumar Busapogula; A. Rakesh; K. Sailaja; P Nithin Linga Reddy

doi:10.53730/ijhs.v6nS4.10694

Authors

Dileep Kumar Busapogula Assistant Professor, Department of Pulmonary Medicine, Mediciti Institute of Medical Sciences) Telangana state, 501401
A. Rakesh Assistant Professor, Department of Pulmonary Medicine, Mediciti Institute of Medical Sciences,Telangana state, 501401
K. Sailaja Professor & HOD, Department of Pulmonary Medicine, Mediciti Institute of Medical Sciences, Telangana state, 501401
Nithin Linga Reddy P
nitinreddy9798@gmail.com
Assistant professor, Department of General medicine, MediCiti institute of medical sciences, Hyderabad, Telangana state, 501401

Keywords:

arterial blood gas, acute exacerabation, chronic obstructive pulmonary disease, arterial oxygen content, endotracheal intubation, non-invasive ventilation

Abstract

Background- Chronic Obstructive Pulmonary disease (COPD) as defined by Global Initiative for Obstructive Lung Disease (GOLD) is a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Objectives-To evaluate outcome of NIV in terms ofTime for reversion of pH to normal, Duration of NIV, Hospital stay, Failure of NIV, Mortality and to compare the effect of noninvasive mechanical ventilation (NIV) in severelyacidotic (pH < 7.25) with mildly acidotic (pH 7.25–7.35) patients with acute hypercapnic chronic obstructive lung disease (COPD) Methods-This is a prospective observational study of COPD patients with acute Type 2 respiratory failure initiated on NIV conducted in Christian Medical College, Vellore, Tamil Nadu. The study was conducted in the Department of Pulmonary Medicine, Christian Medical College, Vellore.Assuming the mean as 12h (SD=6h), the sample size is Hence it is decided to sample 25 mild acidosis and 25 severe acidosis cases for this study. In the present study, 53 patients were recruited from April 2017 to June 2018.

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References

Ajay Verma ,Myank Mishra, Suryakant et al Noninvasive mechanical ventilation: An 18-month experience of two tertiary care hospitals in north India. Lung India 2013,vol 30 issue4:307-311.

Ananda, A., Baso, Y. S., Hidayanty, H., Syarif, S., Aminuddin, A., & Bahar, B. (2022). Providing education chronic energy deficiency (CED) uses web-based she smart to improve knowledge, attitudes, and practice in adolescent girls. International Journal of Health & Medical Sciences, 5(1), 56-62. https://doi.org/10.21744/ijhms.v5n1.1833

Avdeev SN, Tret'iakov AV, Grigor'iants RA, Kutsenko MA, Chuchalin AG. Study of the use of noninvasive ventilation of the lungs in acute respiratory insufficiency due exacerbation of chronic obstructive pulmonary disease. AnesteziolReanimatol 1998:45-51.

British Thoracic Society Standards of Care Com- mittee. Non-invasive ventilation in acute respiratory failure. Thorax 2002;57:192–211.

Brochard L, Isabey D, Piquet J, et al. Reversal of acute exacerbations of chronic obstructive lung disease by inspiratory assistance with a face mask. N Engl J Med 1990;323:1523–30.

Brochard L, Manceboi, Sibbald Wi, et al. Non-invasive ventillation for acute exacerbations of chronic obstructive pulmonary disease. N. Eng. J. Med., 1995;333:817-22.

Celikel T, Sungur M, Ceyhan B, et al. Comparison of non-invasive positive pressure ventilation in acute respiratory failure. Chest. 1998;114:1636–4.

Elliott MW. Domiciliary non-invasive ventilation in stable COPD? Thorax 2009;64:553–6.

Fionnuala Crummy, Catherine Buchan, Belinda Miller, Jo Toghill, and Matthew T. Naughton. "The Use of Noninvasive Mechanical Ventilation in COPD with Severe Hypercapnic Acidosis." Respiratory Medicine 101.1 (2007): 53-61

Jubran A, Tobin MJ. Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation. Am J Re- spir Crit Care Med 1997;155:906–15.

Laghi F, Jubran A, Topeli A, et al. Effect of lung vol- ume reduction surgery on diaphragmatic neurome- chanical coupling at 2 years. Chest 2004;125: 2188–95.

Nava S, Ambrosino N, Rubini F, et al. Effect of nasal pressure support ventilation and external PEEP on diaphragmatic activity in patients with severe sta- ble COPD. Chest 1993;103:143–50.

Organized jointly by the American Thoracic Soci- ety, European Respiratory Society, European Soci- ety of Intensive Care Medicine. International consensus conferences in intensive care medicine: noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 2001;163:283–91.

Plant PK, Owen JL, Elliot MW. Early use of non-invasive ventillation for acute exacerbations of chronic obstructive pulmonary diseaseon general respiratory wards: a multicentre randomized controlled trial. Lancet., 2000;355:1931-5.

Polkey MI, Moxham J. Noninvasive ventilation in the management of decompensated COPD. Monaldi Arch Chest Dis 1995;50:378–82.

Purro A, Appendini L, Polillo C, et al. Mechanical determinants of early acute ventilatory failure in COPD patients: a physiologic study. Intensive Care Med 2009;35:639–47.

Role of BiPAP in acute respiratory failure due to acute exacerbation of COPD. N Rizvi N Mehmood, N Hussain JPMA 51:414,2001.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949