The burden estimation of hepatitis B & C in thalassemia patients in MGM Medical College and Hospital, Jamshedpur

Piyalee Gupta; Ravindra Kumar Barnwal; Anita Sundi; Sana Irfan

doi:10.53730/ijhs.v6nS5.10713

Authors

Piyalee Gupta
drpiyalee@gmail.com
Assistant Professor, Department of Microbiology, Principal Investigator VRDL, MGM Medical College, Jamshedpur
Ravindra Kumar Barnwal Assistant Professor, Department of Microbiology, NMCH, Jamuhar, Sasaram Rohtas (Bihar)
Anita Sundi Tutor, Department of Microbiology, MGM Medical College, Jamshedpur
Sana Irfan Scientist Non-Medical, VRDL, MGM Medical College, Jamshedpur

Keywords:

Hepatitis B & C, Thalassemia, ELISA nucleic acid Amplification testing

Abstract

Introduction: Thalassemia encompasses a group of genetic blood disorders, in which there is altered or inadequate haemoglobin synthesis and requires a repeated blood transfusion. Due to repeated blood transfusion, these patients are vulnerable to HCV, HBV, and HIV like blood transfusion transmitted diseases. Aims and Objective: To determine the prevalence of HCV and HBV infections in multitransfused thalassemia patients in a tertiary care hospital. Material And Methods: Cross sectional and observational studywas done on a total of 110 beta thalassemia patients aged between 2-25years &were categorised into four groups (2-7 years, group 1; 8-13 years, group 2; 14-19 years, group 3 and 20-25 years, group 4).For testing, 5 ml Blood sample was collected, Serum separatedand subjected to testing for HBsAg, and antibody to Hepatitis C, by ELISA method. Screening was done by immunochromatography test (point of care test). Results: A total of 110 patients of beta thalassemia major were included in our study. Out of this, 68(62%) were males and 42(38%) were females.

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