Differences in serum lactate levels, AKI incidence, and intraoperative fluid therapy based on GDFT and standards in major laparotomy surgery patients
Keywords:
serum lactate levels, acute kidney injury incidence, intraoperative fluid therapy, goal directed fluid therapy (GDFT), major laparotomy surgery patientsAbstract
This study aimed to analyze the differences in serum lactate levels and the incidence of Acute Kidney Injury (AKI) in GDFT-based and standard liquid therapy in major laparotomy surgery with general anesthesia at Dr Soetomo Hospital. The type of research and research design used is a randomized clinical trials. The research design is an experimental study design. The observed study variables were then followed during surgery up to 48 hours after surgery for data retrieval and measurement. Patients covered by the study were patients who underwent elective major laparotomy at GBPT of Dr Soetomo Hospital. The results revealed that the administration of crystalloid solutions in the standard group was more than that of the GDFT group, while the administration of colloidal solutions in the standard group was less than that of the GDFT group. Intraoperative fluid balance in the standard group were larger compared to the GDFT group. The standard group had higher levels of postoperative serum lactate than the GDFT group (p < 0.001). The incidence of AKI in the standard group was 4 (18.2%) and no AKI incidence was found in the GDFT group.
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Bellamy, M. C. (2006). Wet, dry or something else? British Journal of Anaesthesia, 97(6), 755–757. https://doi.org/10.1093/bja/ael290
Bijker, J. B., Van Klei, W. A., Kappen, T. H., Van Wolfswinkel, L., Moons, K. G. M., & Kalkman, C. J. (2007). Incidence of intraoperative hypotension as a function of the chosen definition: Literature definitions applied to a retrospective cohort using automated data collection. Anesthesiology, 107(2), 213–220. https://doi.org/10.1097/01.anes.0000270724.40897.8e
Brandstrup, B., Tønnesen, H., Beier-Holgersen, R., Hjortsø, E., OØrding, H., Lindorff-Larsen, K., Rasmussen, M. S., Lanng, C., Wallin, L., Iversen, L. H., Gramkow, C. S., Okholm, M., Blemmer, T., Svendsen, P. E., Rottensten, H. H., Thage, B., Riis, J., Jeppesen, I. S., Teilum, D., … Pott, F. (2003). Effects of Intravenous Fluid Restriction on Postoperative Complications: Comparison of Two Perioperative Fluid Regimens - A Randomized Assessor-Blinded Multicenter Trial. Annals of Surgery, 238(5), 641–648. https://doi.org/10.1097/01.sla.0000094387.50865.23
Bundgaard-Nielsen, M., Jørgensen, C. C., Secher, N. H., & Kehlet, H. (2010). Functional intravascular volume deficit in patients before surgery. Acta Anaesthesiologica Scandinavica, 54(4), 464–469. https://doi.org/10.1111/j.1399-6576.2009.02175.x
Butterworth, J. F., Mackey, D. C., & Wasnick, J. D. (2018). Morgan & Mikhail’s Clinical Anesthesiology (6th ed., Issue 6th). Mc Graw Hill Education.
Cesur, S., Çardaközü, T., Kuş, A., Türkyılmaz, N., & Yavuz, Ö. (2019). Comparison of conventional fluid management with PVI-based goal-directed fluid management in elective colorectal surgery. Journal of Clinical Monitoring and Computing, 33(2), 249–257. https://doi.org/10.1007/s10877-018-0163-y
David, M., Styliani, M., Nicolas, D., & Martin, H. (2020). Defining Major Surgery : A Delphi Consensus Among European Surgical Association (ESA) Members. World Journal of Surgery, March. https://doi.org/10.1007/s00268-020-05476-4
Deng, Q. W., Tan, W. C., Zhao, B. C., Wen, S. H., Shen, J. T., & Xu, M. (2018). Is goal-directed fluid therapy based on dynamic variables alone sufficient to improve clinical outcomes among patients undergoing surgery? A meta-analysis. Critical Care, 22(1). https://doi.org/10.1186/s13054-018-2251-2
Doherty, M., & Buggy, D. J. (2012). Intraoperative fluids: How much is too much? British Journal of Anaesthesia, 109(1), 69–79. https://doi.org/10.1093/bja/aes171
Giglio, M., Dalfino, L., Puntillo, F., & Brienza, N. (2019). Hemodynamic goal-directed therapy and postoperative kidney injury: An updated meta-analysis with trial sequential analysis. Critical Care, 23(1), 1–13. https://doi.org/10.1186/s13054-019-2516-4
Heming, N., Moine, P., Coscas, R., & Annane, D. (2020). Perioperative fluid management for major elective surgery. British Journal of Surgery, 107(2), e56–e62. https://doi.org/10.1002/bjs.11457
Jeffery, A. K., & Nicholas, E. M. (2014). Lactic acidosis. The New England Journal of Medicine, 371(24), 2309–2319. https://doi.org/10.1056/NEJMra1309483
Joshi, G. P. (2020). Enhanced recovery pathways for ambulatory surgery. Current Opinion in Anesthesiology, 33(6), 711–717.
Kellum, J. A., Lameire, N., Aspelin, P., Barsoum, R. S., Burdmann, E. A., Goldstein, S. L., Herzog, C. A., Joannidis, M., Kribben, A., Levey, A. S., MacLeod, A. M., Mehta, R. L., Murray, P. T., Naicker, S., Opal, S. M., Schaefer, F., Schetz, M., & Uchino, S. (2012). Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney International Supplements, 2(1), 1–138. https://doi.org/10.1038/kisup.2012.1
Kendrick, J. B., Kaye, A., Tong, Y., Belani, K., Urman, R. D., Hoffman, C., & Liu, H. (2019). Goal directed fluid therapy in the perioperative setting Julia. Journal of Anaesthesiology Clinical Pharmacology, 34(3), 46–50. https://doi.org/10.4103/joacp.JOACP
Makaryus, R., Miller, T. E., & Gan, T. J. (2018). Current concepts of fluid management in enhanced recovery pathways. British Journal of Anaesthesia, 120(2), 376–383. https://doi.org/10.1016/j.bja.2017.10.011
Miller, T. E., Raghunathan, K., & Gan, T. J. (2014). State-of-the-art fluid management in the operating room. Best Practice and Research: Clinical Anaesthesiology, 28(3), 261–273. https://doi.org/10.1016/j.bpa.2014.07.003
Mitchell, S. C., Vinnakota, A., Deo, S. V., Markowitz, A. H., Sareyyupoglu, B., Elgudin, Y., Medalion, B., Tzagournis, A., Sabik, J., & Park, S. J. (2018). Relationship between intraoperative serum lactate and hemoglobin levels on postoperative renal function in patients undergoing elective cardiac surgery. Journal of Cardiac Surgery, 33(6), 316–321. https://doi.org/10.1111/jocs.13713
Monnet, X., Marik, P. E., & Teboul, J. L. (2016). Prediction of fluid responsiveness: an update. Annals of Intensive Care, 6(1), 1–11. https://doi.org/10.1186/s13613-016-0216-7
Myles, P., Bellomo, R., Corcoran, T., Forbes, A., Wallace, S., Peyton, P., Christophi, C., Story, D., Leslie, K., Serpell, J., McGuinness, S., & Parke, R. (2017). Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): Rationale and design for a multicentre randomised trial. BMJ Open, 7(3), 1–9. https://doi.org/10.1136/bmjopen-2016-015358
Radovic, M., Bojic, S., Kotur-Stevuljevic, J., Lezaic, V., Milicic, B., Velinovic, M., Karan, R., & Simic-Ogrizovic, S. (2019). Serum lactate as reliable biomarker of acute kidney injury in low-risk cardiac surgery patients. Journal of Medical Biochemistry, 38(2), 118–125. https://doi.org/10.2478/jomb-2018-0018
Reddy, E. S., & Rajaratnam, A. (2020). Relaparotomy after caesarean section. Int J Clin Obstet Gynaecol, 4(2), 68–70.
Shah, N. J., Mentz, G., & Kheterpal, S. (2020). The incidence of intraoperative hypotension in moderate to high risk patients undergoing non-cardiac surgery: A retrospective multicenter observational analysis. Journal of Clinical Anesthesia, 66(June), 109961. https://doi.org/10.1016/j.jclinane.2020.109961
Sujatha, P. P., Nileshwar, A., Krishna, H. M., Prasad, S. S., Prabhu, M., & Kamath, S. U. (2019). Goal-Directed vs Traditional Approach to Intraoperative Fluid Therapy during Open Major Bowel Surgery: Is There a Difference? Anesthesiology Research and Practice, 2019. https://doi.org/10.1155/2019/3408940
Suminar, F. D. (2022). Rationality Evaluation of Antibiotic Use In Pediatric Pneumonia At Hospitals In Indonesia. Pharmacology, Medical Reports, Orthopedic, and Illness Details (COMORBID), 1(2), 27–40. https://doi.org/https://doi.org/10.55047/comorbid.v1i2.122
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
Thiele, R. H., Raghunathan, K., Brudney, C. S., Lobo, D. N., Martin, D., Senagore, A., Cannesson, M., Gan, T. J., Mythen, M. M. G., Shaw, A. D., & Miller, T. E. (2016). American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on perioperative fluid management within an enhanced recovery pathway for colorectal surgery. Perioperative Medicine, 5(1), 1–15. https://doi.org/10.1186/s13741-016-0049-9
Walsh, M., Devereaux, P. J., Garg, A. X., Kurz, A., Turan, A., Rodseth, R. N., Cywinski, J., Thabane, L., & Sessler, D. I. (2014). Relationship Between Intraoperative Mean Arterial Pressure and Clinical Outcomes After Noncardiac Surgery. Survey of Anesthesiology, 58(4), 184–185. https://doi.org/10.1097/sa.0000000000000064
Walsh, M., Kurz, A., Turan, A., Rodseth, R. N., Cywinski, J., Thabane, L., Ph, D., & Sessler, D. I. (2013). Relationship between Intraoperative Mean. Anesthesiology, 119(3), 507–515.
Wang, R., Wang, S., Zhang, J., He, M., & Xu, J. (2022). Serum Lactate Level in Early Stage Is Associated With Acute Kidney Injury in Traumatic Brain Injury Patients. Frontiers in Surgery, 8(January), 1–8. https://doi.org/10.3389/fsurg.2021.761166
Yanti, R., Sinrang, A. W., & Aminuddin, A. (2021). Levels of c-reactive protein (CRP) in stunting and non stunting tolls age 36-60 months. International Journal of Health & Medical Sciences, 4(1), 150-154. https://doi.org/10.31295/ijhms.v4n1.1667
Zhao, C. C., Ye, Y., Li, Z. Q., Wu, X. H., Zhao, C., & Hu, Z. J. (2022). Effect of goal-directed fluid therapy on renal function in critically ill patients: a systematic review and meta-analysis. Renal Failure, 44(1), 777–789. https://doi.org/10.1080/0886022X.2022.2072338
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