Assessment of haematological parameters in patients with OSMF
Keywords:
Sahli's method, oral submucous fibrosis, haematological parametersAbstract
Background: Oral submucous fibrosis (OSMF) is an insidious disease affecting any part of the oral cavity and predominantly occurs among Indians. The present study was conducted to assess haematological parameters in patients with OSMF. Materials & Methods: 46 patients of OSMF of both genders and 46 healthy control were selected. Five millilitres of fasting venous blood were obtained to calculate haemoglobin level using and Sahli's method and the ferrone system was used for serum iron levels measurement. The chemiluminescent microparticle intrinsic factor test was used to quantify vitamin B12 in human serum. Results: Group I had 26 males and 20 females and group II had 23 males and 23 females. The mean PCV (%) was 44.3 and 36.2, MCV (fl) was 87.4 and 70.2, MCH (g/dl) was 27.6 and 25.1, MCHC (g/dl) was 32.9 and 28.3, Hb (gm%) was 13.5 and 10.1, iron (mg/dl) was 120.4 and 46.8 and vitamin B12 (pg/Ml) was 426.2 and 226.8 in group II and group I respectively. The difference was significant (P< 0.05). Conclusion: All haematological factors was greatly reduced in OSMF patients.
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Bhardwaj D, Dinkar AD, Satoskar SK, Desai SR. Serum Iron and haemoglobin estimation in oral submucous fibrosis and Iron deficiency anaemia: A diagnostic approach. J Clin Diagn Res 2016;10:54 8.
Huang S, Ling T, Wu H. Experimental study on aqueous areca nut extracts inducing OSMF in rats. Effect of mast cells on collagen metabolism. Hua Xi Kou Qiang Yi Xue Za Zhi 1997;15:94 6.
Ramanathan K. Oral submucous fibrosis e an alternative hypothesis as to its causes. Med J Malaysia 1981;36:243 5.
Ganapathy KS, Gurudath S, Balikai B, Ballal S, Sujatha D. Role of iron deficiency in oral submucous fibrosis: An initiating or accelerating factor. JIAOMR 2011;23:25 8.
Arakeri Thomas D, Aljababa AS, Hunasgi S, Rai KK, Rai KK, Hale B et al. TFM classification and staging of oral submucous fibrosis: A new proposal. J Oral Path Med 2018;47:403 9.
Tsiminis G, Schartner E, Brooks JL, Hutchinson MR. Measuring and tracking vitamin B12: A review of current methods with a focus on optical spectroscopy. Applied Spectroscopy Rev 2017;52:439 55.
More CB, Rao NR. Proposed clinical definition for oral submucous fibrosis. J Oral Biol Craniof Res 2019;9:311 14.
Ranganathan K, Devi MU, Joshua E, Kirankumar K, Saraswati TR. Oral submucous fibrosis: A case control study in Chennai, South India. J Oral Pathol Med 2004;33:274 7.
Babu S, Bhat RV, Kumar PU, et al. A comparative clinicopathological study of oral submucous fibrosis in habitual chewers of pan masala and betel quid. Clin Toxicol 1996;34:317 22.
Shah N, Sharma PP. Role of chewing and smoking habits in the aetiology of oral submucous fibrosis (OSMF): A case control study. J Oral Pathol Med 1998;27:475e 9.
Patil DJ, Joshi M. Evaluation of haematological profile in oral submucous fibrosis: A cross sectional study. J Oral Maxillofac Pathol 2020;24:575.
Manhas A, Showkat I, Tantray S, Parray M. To determine the haematological profile in patients with Oral Submucous Fibrosis. J Adv Med Dent Scie Res 2022;10(4):89-92.
Abidullah M, Gaddikeri K, Anjum B, Vairagare S, Tarani K, Seethamsetty S. Evaluation of Hematological Profile in Oral Submucous Fibrosis. Cureus. 2022 Feb 5;14(2).
Salawali, A. Q. ., Tahir, A. M. ., & Hardjo, M. . (2021). The effect of family education on the fulfillment of family health tasks in handling case of hypertension post earthquake in Sigi regency. International Journal of Health & Medical Sciences, 4(1), 136-140. https://doi.org/10.31295/ijhms.v4n1.1625
Nyandra, M., Kartiko, B.H., Susanto, P.C., Supriyati, A., Suryasa, W. (2018). Education and training improve quality of life and decrease depression score in elderly population. Eurasian Journal of Analytical Chemistry, 13(2), 371-377.
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