Treatment and recurrence in giant cell tumour locally advanced around the knee
A hospital based follow up study
Keywords:
Giant cell tumour (GCT), resection, endoprosthesis, fracture, non-union, expansile cyst, benignAbstract
Background-Giant cell tumour (GCT) is a benign bone tumour with aggressive characteristics. They are more prevalent in the third decade of life and demonstrate a preference for locating in the epiphyseal region of long bones. They have a high local recurrence rate, which depends on the type of treatment and initial tumour presentation. Objective- To evaluate the results of the treatment with regard to relapse. Methods- It was a hospital based follow up study done for periods of 7 months. Fifty patients of GCT were recruited in the study through purposive sampling technique.Study being conducted on patients with followup for 12 months. Demographic profile and all the necessary investigation were done. SPSS ( Version 22.0) was used for analysis. Chi-Square test was used as test of significance. Results-There was a predominance of males (80%). The most common location was the distal femur. All patients presented with pathologic fracture at diagnosis, recurrence seen after 9months of followup.the most common location for GCT was distal femur seen in 84% of patients, while curettage with cement was the most common treatment done in 89% which was statistically significant (p<0.05). Endoprosthesis was done in 11% patient.
Downloads
References
Baptista AM, Camargo AFF, Caiero MT, Rebolledo DCS, CorreiaLFM, Camargo OP. TCG: o que aconteceuapós 10 anosdecuretagem e cimentac ̧ão? Estudorestrospectivo de 46 casos.ActaOrtop Bras. 2014;22(6):308–11.
Baptista PPR. Tratamento do tumor de célulasgigantesporcuretagem, cauterizac ̧ão pela eletrotermia, regularizac ̧ãocombroca e enxertoósseoautólogo. Rev Bras Ortop.1995;30(11/12):819–27.
Becker WT, Dohle J, Bernd L, Braun A, Cserhati M, EnderleA,et al. Local recurrence of giant cell tumor of bone afterintralesional treatment with and without adjuvant therapy. JBone Joint Surg Am. 2008;90(5):1060–7.
Camargo OPO. Estado da arte no diagnóstico e tratamentodotumor de célulasgigantes. Rev Bras Ortop. 2002;37(10):424–9.
Campanacci M, Giunti A, Olmi R. Giant-cell tumours of bone:a study of 209 cases with long term follow up in 130. Ital JOrthopTraumatol. 1975;1:249–77.
Dahlin DC, Cupps RE, Johnson EW Jr. Giant-cell tumor: a studyof 195 cases. Cancer. 1970;25(5):1061–70.
Jani, J. R., Bajamal, A. H., Utomo, S. A., Parenrengi, M. A., Fauzi, A. A., Utomo, B., & Dwihapsari, Y. (2021). Correlation between magnetic resonance imaging (MRI) and dynamic mechanical analysis (DMA) in assessing consistency of brain tumor. International Journal of Health & Medical Sciences, 4(2), 260-266. https://doi.org/10.31295/ijhms.v4n2.1737
Jesus Garcia R. Diagnóstico e tratamento de tumores ósseos.2aed. Rio de Janeiro: Elsevier; 2013.
Jesus-Garcia R, Wajchenberg M, Justino MAF, KorukianM,Yshihara HI, da Ponte FM. Tumor de célulasgigantes, análisedainvasão articular, fraturapatológica, recidiva local emetástase para o pulmão. Rev Bras Ortop. 1997;32(11):849–56.
Klenke FM, Wenger DE, Inwards CY, Rose PS, Sim FH. Giantcelltumor of bone: risk factors for recurrence. ClinOrthopRelat Res. 2011;469(2):591–9.
Klenke FM, Wenger DE, Inwards CY, Rose PS, Sim FH.Recurrent giant cell tumor of long bones: analysis of surgicalmanagement. ClinOrthopRelat Res. 2011;469(4):1181–7.
Lackman RD, Crawford EA, King JJ, Ogilvie CM. Conservativetreatment of Campanacci grade III proximal humerus giant cell tumors. ClinOrthopRelat Res. 2009;467(5):1355–9.
Mello GP, Sonehara HA, Neto MA.Endoprótesenãocimentadanotratamento de tumor de célulasgigantes de tíbia, 18 anosdeevoluc ̧ão. Rev Bras Ortop. 2010;45(6):612–7.
O’Donnell RJ, Springfield DS, Motwani HK, Ready JE, GebhardtMC, Mankin HJ. Recurrence of giant-cell tumors of the longbones after curettage and packing with cement. J Bone JointSurg Am. 1994;76(12):1827–33.
Szendröi M. Giant-cell tumour of bone. J Bone Joint Surg Br.2004;86(1):5–12.
Widana, I.K., Sumetri, N.W., Sutapa, I.K., Suryasa, W. (2021). Anthropometric measures for better cardiovascular and musculoskeletal health. Computer Applications in Engineering Education, 29(3), 550–561. https://doi.org/10.1002/cae.22202
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
