Comparative study of Apelin and Glucose levels in COVID-19 patients

Hind Ahmed Kenoosh; Muthanna Mohammed Awad

doi:10.53730/ijhs.v6nS6.10990

Authors

Hind Ahmed Kenoosh
hind.a.knoosh97@gmail.com
Department of Biology College of Education for Pure Sciences, University of Anbar, Anbar, Iraq
Muthanna Mohammed Awad Department of Biology, College of Education for Pure Sciences, University of Anbar, Anbar, Iraq

Keywords:

adipokine, apelin, COVID-19, diabetes mellitus, glucose

Abstract

A novel coronavirus, known as Severe Acute Respiratory Syndrome- Coronavirus 2, has just emerged as an epidemic danger to worldwide public health, Diabetes increases the severity and mortality rate of COVID-19. Adipokines perform a hormonal function including apelin is the newest finding among adipokines and has drawn much Research interest about its functions. This study aimed to estimate the level of apelin hormone in Covid-19 patients and the relationship of this hormone to the level of glucose. The study included 65 patients and 23 healthy as a control group. Apelin hormone was determined by ELISA technique, the level of the hormone Apelin elevated in male and female Covid-19 patients (3752.8571±81.60529, and 3786.3333±96.92097 respectively pg\ml) when compared to the control group for males and females (112.8462±7.79287, and 151.3000±22.20913 respectively pg\ml), High level of glucose in male and female patients (122.2000±9.703, 145.6667±11.55 mg/dl respectively) when compared to healthy males and females (90.8462±6.346, 102.3000±7.701 mg /dl respectively). This study shows a very high increase of apelin hormone in Covid-19 patients compared to healthy. it can be used as a predictive biomarker for the risk of deterioration and disease progression. also, It has an important role in managing COVID-19 patients.

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