An evaluation of lipid profile in patients with metabolic syndrome at a tertiary care teaching hospital based in Tamilnadu
Keywords:
Dyslipidemia, Metabolic Syndrome, Type II diabetes, Lipid Profile, Metabolic risk factors, TGL, HDLAbstract
Background: Metabolic risk factors contributing are abdominal obesity, dyslipidemia, hypertension, elevated plasma glucose, pro-thrombotic state and proinflammatory state. Diabetes mellitus (DM), a metabolic disorder caused by impaired insulin secretion, peripheral insulin resistance or both, has become a major public health problem in India. Aims and Objectives: To evaluate the lipid profile in patients with Metabolic Syndrome at a tertiary health care centre Tamilnadu. Materials and methods: This is a cross-sectional study carried out in the Department of Medicine, Shri Sathya Sai Medical College and Research Institute in Patients diagnosed with Metabolic syndrome were identified and randomly selected in all age groups. 50 metabolic syndrome patients (Cases) and age matched 50 normal patients (Controls) were enrolled into the study with written explained consent. All patients underwent lipid profile testing and fasting and post -prandial sugar level as per standard protocol. Statistical analysis was done with unpaired t-test and chi-square test using SPSS version 19 software. Results and Observations: our study contains that the majority of the patients were in the age group 61-70y – 42%, 50-60y.29%, >70y 13% similarly controls were also 60-70y- 38%, 50-60y -29%, >70y were 8% and hence both the cases and controls were comparable with age (p>0.05).
Downloads
References
Agarwal A, Jain V, Singla S, Baruah B, Arya V, Yadav R. Prevalence of nonalcoholic fatty liver disease and its correlation with coronary risk factors in patients with type 2 diabetes. J Assoc Physicians India. 2011;59:351–4.
Alberti KG, Zimmet PZ, Shaw J. Metabolic syndrome; a new world-wide definition. A consensus statement from the international Diabetes federation. Diabet Med. 2006; 23: 469-80.
American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus, Diabetes Care. 2011,34,62-9.
Amod L. Borle, Neeraj Chhari, Girjesh Gupta. Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India. International Journal of Community Medicine and Public Health Borle AL et al. Int J Community Med Public Health. 2016 Jan;3(1):140-144
Braunwald E. Hypertension. In: Douglas P. Zipes, Peter Libby, Robert O. Bonow, Eugene Braunwald, eds. Braunwald’s Heart Disease: a Textbook of Cardiovascular Medicine. 7th ed. Philadelphia: Saunders; 2005: 1953.
Despres JP. Health consequences of visceral obesity. Ann Med. 2001;33:534-41.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc. 2001; 258: 2486-97.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults. Findings from the Third National Health and Nutrition Examination Survey. JAMA. 2002;287:356-9.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung and Blood Institute Scientific Statement. Circulation. 2005;112:2735-2752.
Grundy SM, Metabolic syndrome scientific statement by the American Heart Association and the National Heart, Lung, and Blood Institute. Arterioscler Thromb Vasc Biol. 2005;25:2243-2244.
Guerrero, J. A. A., Moreira, J. A. M., Zambrano, M. J. Z., Rivas, F. E. C., & Pilligua, M. L. B. (2021). Applied neuroscience in early childhood and high school education. International Journal of Social Sciences and Humanities, 5(3), 223–231. https://doi.org/10.53730/ijssh.v5n3.2027
Lestari, Y. D., Armi, A., Koniasari, K., Setiawan, Y., Sartika, M., Rohmah, H. N. F., Nurpratiwi, Y., & Fahrudin, A. (2022). Effectiveness of the emotional freedom techniques to reducing stress in diabetic patients. International Journal of Health Sciences, 6(2), 555–562. https://doi.org/10.53730/ijhs.v6n2.6728
Mahaling DU, Basavaraj MM, Bika AJ. Comparison of lipid profile in different grades of non-alcoholic fatty liver disease diagnosed on ultrasound. Asian Pac J Trop Biomed. 2013;3(11):907–12.
Metabolic syndrome. Acessed online at : October 2018 : available at ; https://www.mayoclinic.org/diseasesconditions/metabolic-syndrome/symptoms-causes/syc20351916 .
Pankaj J. Akholkar, Amita A. Gandhi, Chirag M. Shah. The metabolic syndrome among hypertensive patients: a cross-sectional study. International Journal of Advances in Medicine Akholkar PJ et al. Int J Adv Med. 2015 Aug; 2(3):188-191
Pardhe, et al. BMC Gastroenterology. 2018;18:109. Available:https://doi.org/10.1186/s12876- 018-0843-6
Pouliot MC, Despres JP, Nadeau A, Moorjani S, Prud Homme D, Lupien PJ, et al. Visceral obesity in men.Association with glucose tolerance, plasma insulin and lipoprotein levels. Diabetes. 1992; 41: 826-34.
Ramachandran A, Snehalatha C. Current scenario of diabetes in India, J. Diabetes. 2009; 1(1):18-8.
Reaven GM. Bunting lecture 1988, Role of insulin resistance in human disease. Diabetes. 1988; 37: 1595- 607.
Reisin E, Alpert MA. Definition of the metabolic syndrome: Current proposals and controversies. Am J Med Sci. 2005; 330:269-272.
Reynolds K, He J. Epidemiology of the metabolic syndrome. Am J Med Sci. 2005; 330:273-279.
Sheshiah V, Balaji V. A handbook on Diabetes Mellitus. 6th ed. New Delhi: all india publishers and distributers. 2013:29-54.
Souza MR, Diniz MF, Medeiros JE, Araujo MS. Metabolic syndrome and risk factors for non-alcoholic fatty liver disease. Arq Gastroenterol. 2012;49:89– 96.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








