Bacteriological study of non-fermenters and their antibiogram in tertiary care hospital
Keywords:
NFGNB-non-fermenting gram-negative bacilli, UTI-urinary tract infection, RTI-respiratory tract infectionAbstract
Non –fermenting Gram-negative bacilli are a group of heterogeneous, aerobic, nonsporing bacteria. They are saprophytes in nature and are also found as commensals in man and other animals. This study aims to isolate and identification of NFGNB from various clinical specimens and to find out their clinical significance among the in-patients admitted at Vijayanagar Institute of Medical Sciences, Bellary. 110 isolates from various age groups and sexes were included in the study. A detailed history was elicited and the clinical specimens were collected under aseptic precaution and subjected to preliminary biochemical tests and further speciation was done. In the present study commonest isolates were Pseudomonas aeruginosa, Acinetobacter baumannii, Acinetobacter haemolyticus, Pseudomonas fluorescence, Acinetobacter lwoffi Acinetobacter junii, Acinetobacter radioresistant and from urinary tract infection which accounted for (34.5%), followed by respiratory tract infection (21.2%), local infection (20.9%), Post operative infection (8.18%), infection related to the abdomen (6.36%), Septicemia (5.45%), and post-traumatic infection (2.7%) in decreasing order of frequency. They showed variability in their antibiotic susceptibility results, Most of them were sensitive to Carbapenem groups of drugs.
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1.Washington Winn Jr, Stephen Allen, William Janda, Elmer Könemann, Gary Procop, Paul Schreckenberger, Gail Woods. The Nonfermentive Gram Negative Bacilli. 6th edition, 2006. Koneman’s Color Atlas and Textbook of Diagnostic Microbiology; p305-376.
16. Jawad A, Seifert H, Snelling AM, Heritage J, Hawkey PM. Survival of Acinetobacter baumanii on Dry surfaces: Comparison of Outbreak and Sporadic Isolates. J Clin Microbiol 998; 36:1938-1941.
19. Gupta E, Mohanty S, Sood S, Dhawan B,Das BK, Kapil A. Emerging resistance to Carbapenems in a tertiary care hospital in north india. Ind J Med Res 2006; 124:95 98.
8.Gardener P, Griffin WB, Swartz MN, Kunz LJ. Nonfermenting Gram- Negative Bacilli of Nosocomial Interest. Amer J Med 1970; 48:735-749.
Algun U, Arisoy A, Gunduz T, Ozbakkaloglu B. The resistance of Pseudomonas aeruginosa strains to fluoroquinolone group of antibiotics.Ind J Med Microbiol 2004; 22:112-114.
Chang-Tai Z, Yang L, Zhong –Yi H, Chang –Song Z, Yin-Ze K, Yong-Ping L, Chun –Lei D. High frequency of integrons related to drug –resistance in clinical isolates of Acinetobacter baumannii Ind J Med Microbiology 2011;29(2):118-23.
Cristane-Frosta CC,Moneira JLB.Frequency of Nonfermentative Gram-Negative Bacilli isolated from clinical materials of Pacients at Universidade federal Do Ceara Hospital Complex-Brazil.Rev Microbiol 1998;29:
Fu W,Demei Z,Shi W,Fupin H,Yingyuan Z.The susceptibility of non-fermentative Gram-negative bacilli to cefoperazone and sulbactam compared with other antibacterial agents. International J of Antimicrobial Agents 2003; 22:444-448.
Jayanthi. S and Jeya .M.Clinical distribution and antibiotic resistance pattern of Non-Fermenting Gram-negative bacilli.International Journal of Pharma and Bio Sciences.Vol3/Issue1/ Jan-Mar 2012.
Levin MH, Olson B, Nathan C, Kabins SA, Weinstein RA. Pseudomonas in the sinks in an intensive care unit: relation to patients.J Clin Pathol 1984;37:424-427.
Malini A, Deepa EK, Gokul BN, Prasad SR. Nonfermenting gram-negative bacilli infections in a tertiary care hospital in Kolar, Karnataka. J Lab physicians; 2009; 1: 62-66.
Mohammad Rahbar,Hadi Mehrgan, Negar Haji Aliakbhari.Prevalence of antibiotic-resistant Acinetobacter baumannii in a 1000-bed tertiary care hospital in Tehran , Iran.Indiian Journal of Pathology and Microbiology-53(2), April-June2010.
Pollack M.Infections due to Pseudomonas species and related organism.In: Fauci,Braunwald,Isselbacher,Wilson,Martin,Kasper,Hauser,Longo,editors.Principles of Internal Medicine.18th edition vol.I,New York:McGrawHill 2005;943-950.
Prakash KS, Chaudhary M, Kashyap B, Kumari T, Sharma VK. Imipenem Resistant Pseudomonas aeruginosa. A preliminary report. J Acad Clin Microbiol 2005; 7:27-30.
Prashant K. Parandekar and Basvaraj V. Peerapur. Non-Fermenters in Human Infections with Special Reference to Acinetobacter Species in a Tertiary Care Hospital from North Karnataka, India; JKIMSU, (2012), Vol. 1 (1) 84-88.
Quinn JP.clinical problems posed by multiresistant non-fermenting gram-negative pathogens. Clin Infect Dis 1998; 27:117-124
Rajan R, Saramma TI. Isolates of Pseudomonas aeruginosa from clinical specimens. J Acad clin Microbiol 2001; 3:11-15.
Sachdev HS,Deb M.Acinetobacter meningitis:case Report with review of Literature.Ind Paediatr 1980;17:551-555.
Shoba KL, Gowrish G Rao, Anand M Kukkamalla..Prevalence of Non-fermenters in ` Urinary tract Infections In a Tertiary care Hospital. Web med Central MICROBIOLOGY 62011;2(1): WMC001464 p2-4.
Smitha S,Lalitha P,Prajna VN,Srinivasan M.Susceptibility trends of Pseudomonas Species from corneal ulcers.Ind J Med Micribiol 2005;23:168-171.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937
Taneja N, Maharwal S, Sharma M. Imipenem Resistant in Non-Fermenters causing nosocomial Urinary tract infection. Ind J Med Sci 2003; 57:294-299.
Troillet N, Samore M H,Carmeli Y. Imipenem resistant Pseudomonas aeruginosa; risk factors and antibiotic susceptibility pattern. Clin Infect Dis 1997; 25:1094-1098.
Vijaya D, Kamala, Bavani S, Veena M. Prevalence of non-fermenters in clinical specimens. Indian J. Med. Sci:2000; 54: 87-91.
Wisplinghoff H, Perbix W, Seifert H. Risk factors for Nosocomial Bloodstream Infections Due to Acinetobacter baumanii:A Case-Control Study of Adult Burn Patients. Clin Infect Dis 1999; 28:59-66.
Yanti, R., Sinrang, A. W., & Aminuddin, A. (2021). Levels of c-reactive protein (CRP) in stunting and non stunting tolls age 36-60 months. International Journal of Health & Medical Sciences, 4(1), 150-154. https://doi.org/10.31295/ijhms.v4n1.1667
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