Phytodentistry: A nature’s gift to dentist!!!!
Keywords:
Plants, Extract, Phytodentistry, Treatment, Dental DiseaseAbstract
Oral cavity harbours more than 700 species of micro-organisms. Imbalance in acidogenic and aciduric bacterial causes initiation of Dental caries whereas anaerobic bacteria lead to periodontal disease. Treatment of these diseases use of various chemicals which may have unpleasant taste, allergic reaction or toxicity even can cause financial burden. To overcome this, alternative therapeutical agents which are safer to oral tissues as well as economical. Plants can be better alternative and they are used as Medicine since ages. Ayurveda and Chinese traditional medicine has mentioned the various medicinal properties of these plants. The use of plants / their products can be dated through old eras like use of neem bark or miswak for cleaning the teeth, use of clove oil for dental pain relief. In Ayurveda, methods like Dant Dhavani, Jivha Lekhana, Gandusha and Tissue regeneration therapies are recommended for oral health and involves use of plant or plant extract. Each Plant is the power house of the various chemicals known as phytochemicals which have numerous medicinal actions. Application of these phytochemicals in the dental science is the Phytodentistry. Phytodentistry can be expounded as the use of plants and their extract for the treatment or prevention of various dental diseases.
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Wikipedia. Phytotherapy. Available at: http://en.wikipedia. org/w/index.php?title=Phytotherapy&oldid=493479031. Accessed: 22 May 2012.
Marshall RJ, Gee R, Israel M et al. The use of alternative therapies by Auckland general practitioners. NZMJ 1990, 103: 213–215.
Gupta R, Ingle NA, Kaur N, Yadav P, Ingle E, Charania Z. Ayurveda in dentistry: A review. J Int Oral Health 2015;7 (8):141-3.
Consult M. Complementary and alternative medicine. Clinical topic tours. St. Louis: Elsevier; 2003.
Chopra RN, Nayar SL, Chopra IC. Glossary of Indian medicinal plants. New Delhi: Council of Scientific and Industrial Research, 1956
Patwardhan BK. Ayurveda: The 'Designer' medicine: A review of ethnopharmacology and bioprospecting research. Indian Drugs. 2000; 37(5):213-27.
Kumar G, Jalaluddin MD, Rout P, et al. Emerging trends of oral care in dentistry. J Clin Diagn Res. 2013; 7(8):1827-9.
Athavale VB. Dant rogas. In: Athavale VB, editor. Dentistry in Ayurveda. 1st ed. New Delhi: Chaukhamba Sanskrit Pratishthan; 1999. p. 7 11.
Naik GH, Priyadarsini KI, Satav JG, Banavalikar MM, Sohoni DP, Biyani MK, et al. Comparative antioxidant activity of individual herbal components used in Ayurvedic medicine. Phytochemistry 2003;63:97 104.
Venugopal T, Kulkarni VS, Nerurker RA, Damle SG, Patnekar PN. Epidemiological study of dental caries. Indian J Pediatr 1998;65:883
Kadam A, Prasad BS, Bagadia D, Hiremath VR. Effect of Ayurvedic herbs on control of plaque and gingivitis: Arandomized controlled trial. Ayu 2011;32:532 5.
Asokan S. Oil pulling therapy. Indian J Dent Res 2008;19 :169.
Amith HV, Ankola AV, Nagesh L. Effect of oil pulling on plaque and gingivitis. J Oral Health Community Dent 2007;1: 12 8.
Asokan S, Emmadi P, Chamundeswari R. Effect of oil pulling on plaque induced gingivitis: A randomized, controlled, triple blind study. Indian J Dent Res 2009;20: 47 51.
Amruthesh S. Dentistry and Ayurveda V: An evidence based approach. Indian J Dent Res. 2011;2:3 9.
Hotwani K, Baliga S, Sharma K. Phytodentistry: use of medicinal plants. J Complement Integr Med. 2014 Dec;11(4):233-51. doi: 10.1515/jcim-2013-0015. PMID: 25153610.
Jain, Nitul & Yogesh, Chand & Batra, Manu & Himanshu, Pratap & Bhandari, Ravi & Agarwal, Prerna.. Dentistry: Turning towards Herbal Alternatives: A Review. Sch. J. App. Med. Sci., 2014; 2(1C):253-257
Iyer M, Gujjari AK, Rao RN, Gowda DV, Srivastava A. Biomedical applications of phytomedicines: Dental perspective. Dent Hypotheses 2016;7:34-41.
Dua A, Garg G, Nagar S, Mahajan R. Methanol extract of clove (Syzygium aromaticum Linn.) damages cells and inhibits growth of enteropathogens. J Innov Biol. 2014;1(4):200-205.
Shah A, Jani M, Shah H, Chaudhary N, Shah A. Antimicrobial effect of clove oil (Luang) extract on Enterococcus faecalis. Journal of Advanced Oral Research. 2014;5(3):36-38.
.Li HY, Lee BK, Kim JS, Jung SJ, Oh SB. Eugenol inhibits ATP—induced P2X currents in trigeminal ganglion neurons. Korean J Physiol Pharmacol. 2008;12(6):315-321.
Skidmore-Roth L. Mosby’s Handbook of Herbs & Natural Supplements. 3rd ed. St. Louis, MO: Elsevier Health Sciences; 2005.
Adyanthaya A, Ismail S, Sreelakshmi N. Indian traditional medicinal herbs against dental caries – an unsung past to a bright future, Saudi J Oral Dent Res. 2016;1(1):1-6.
Bhatia M, Urologain SS, Pentyala KB, Urologain SB, Menka KB, Bhoi S. Novel Therapeutic Approach for the Treatment of Periodontitis by Curcumin. J Clin Diag Res 2014;8(12):65-9.
Scrobota I, Bolfa P, Filip AG, et al. Natural chemopreventive alternatives in oral cancer chemoprevention. J Physiol Pharmacol. 2016; 67(1):161-72.
26. Lee UL, Choi SW. The Chemopreventive properties and therapeutic modulation of green tea polyphenols in Oral Squamous Cell Carcinoma. ISRN Oncol. 2011;2011 :1–7.
Akram, Muhammad & Afzal, Arslan & Khan, U. & Abdul, H. & Mohiuddin, Ejaz & Asif, Muhammad. Curcuma longa and Curcumin: A review article. Rom. J. Biol-Plant Biol.2010, 55: 65-70.
Mali AM, Behal R, Gilda SS. Comparative evaluation of 0.1% turmeric mouthwash with 0.2% chlorhexidine gluconate in prevention of plaque and gingivitis: A clinical and microbiological study. J Indian Soc Periodontol. 2012; 16(3):386-391. doi:10.4103/0972-124X.100917.
Jaswal R, Dhawan S, Grover V, Malhotra R. Comparative evaluation of single application of 2% whole turmeric gel versus 1% chlorhexidine gel in chronic periodontitis patients: A pilot study. J Ind Soc Periodontol 2014;18(5):575-80.
Behal R, Mali AM, Gilda SS, Paradkar AR. Evaluation of local drug-delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: A clinical and microbiological study. J Indian Soc Periodontol. 2011;15(1):35-8. doi: 10.4103/0972-124X.82264. PMID: 21772719; PMCID: PMC3134044.
Dr.Viddyasagar Mopagar, Dr.Priyenka Patil, Dr.Neeta Padmawar ,Dr.Sourabh Joshi Dr. Asha Nara, Dr. Prajakta Joshi. Comparative Assessment Of Periodontal Ligament Cell Viability Using Three Different Storage Media For Avulsed Teeth. International Journal Of Scientific Research 2018,7(6):37-40.
Purohit RN, Bhatt M, Purohit K, Acharya J, Kumar R, Garg R. Clinical and Radiological Evaluation of Turmeric Powder as a Pulpotomy Medicament in Primary Teeth: An in vivo Study. Int J Clin Pediatr Dent 2017;10(1):37-40.
Sotomil JM, Münchow EA, Pankajakshan D, Spolnik KJ, Ferreira JA, Gregory RL, Bottino MC. Curcumin-A Natural Medicament for Root Canal Disinfection: Effects of Irrigation, Drug Release, and Photoactivation. J Endod. 2019 Nov;45(11):1371-1377. doi: 10.1016/j.joen.2019.08.004.
Surjushe A, Vasani R, Saple DG. Aloe vera: A short review. Indian J Dermatol 2008;53:163‑6.
35.Ali S, Wahbi W. The efficacy of aloe vera in management of oral lichen planus: a systematic review and meta-analysis. Oral Dis. 2017 Oct;23(7):913-918. doi: 10.1111/odi.12631. Epub 2017 Feb 8. PMID: 28029732.
Anuradha A, Patil B, Asha VR. Evaluation of efficacy of aloe vera in the treatment of oral submucous fibrosis - a clinical study. J Oral Pathol Med. 2017 Jan;46(1):50-55. doi: 10.1111/jop.12463. Epub 2016 Jun 17. PMID: 27314762.
Babaee N, Zabihi E, Mohseni S, Moghadamnia AA. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. Dent Res J (Isfahan). 2012;9(4):381-5. PMID: 23162576; PMCID: PMC3491322.
Ajmera N, Chatterjee A, Goyal V. Aloe vera: It's effect on gingivitis. J Indian Soc Periodontol. 2013 Jul;17(4):435-8. doi: 10.4103/0972-124X.118312. PMID: 24174720; PMCID: PMC3800403.
Bovik EG. Aloe vera: Panacea or old wives tales? Tex Dent J. 1966;84:13–6.
Bhat G, Kudva P, Dodwad V. Aloe vera: Nature's soothing healer to periodontal disease. J Indian Soc Periodontol. 2011 Jul;15(3):205-9. doi: 10.4103/0972-124X.85661. PMID: 22028505; PMCID: PMC3200013.
Athiban PP, Borthakur BJ, Ganesan S, Swathika B. Evaluation of antimicrobial efficacy of Aloe vera and its effectiveness in decontaminating gutta percha cones. J Conserv Dent. 2012 Jul;15(3):246-8. doi: 10.4103/0972-0707.97949.
Subramanyam D, Somasundaram S. Clinical and Radiographic Evaluation of Aloe vera vs Formocresol as a Pulpotomy Medicament in Primary Molars: A Double Blinded Randomized Controlled Trial. Int J Clin Pediatr Dent. 2020 Mar-Apr;13(2):138-143. doi: 10.5005/jp-journals-10005-1724..
Gonna S, Ghoname N, Kabbash A, Yagi A. Efficacy of Aloe Vera as A Pulpotomy Agent in Children Primary Teeth: Clinical and Radiographic Studies. Journal of Gastroenterology and Hepatology Research 2019; 8(5): 2946-2951. doi:http://www.ghrnet.org/index.php/joghr/article/view/
Khairwa A, Bhat M, Sharma R, Satish V, Maganur P, Goyal AK. Clinical and radiographic evaluation of zinc oxide with aloe vera as an obturating material in pulpectomy: an in vivo study. J Indian Soc Pedod Prev Dent. 2014;32 (1):33-8. doi: 10.4103/0970-4388.127051. PMID: 24531599.
Moore TE. Aloe vera: Its Potential Use in Wound Healing and Disease Control in Oral Conditions.
Tello CG, Ford P, Iacopino AM. In vitro evaluation of complex carbohydrate denture adhesive formulations. Quintessence Int. 1998 Sep;29(9):585-93. PMID: 9807143.
Sudarshan R, Annigeri RG, Sree Vijayabala G. Aloe vera in the treatment for oral submucous fibrosis - a preliminary study. J Oral Pathol Med. 2012 Nov;41(10):755-61. doi: 10.1111/j.1600-0714.2012.01168.x.
Moore TE. The M and M's of aloe vera--is it for dentistry? J Okla Dent Assoc. 2001 Winter; 91(3):30-1, 36. PMID: 11314178.
Mangaiyarkarasi SP, Manigandan T, Elumalai M, Cholan PK, Kaur RP. Benefits of Aloe vera in dentistry. J Pharm Bioallied Sci. 2015 Apr; 7(Suppl 1):S255-9. doi: 10.4103/0975-7406.155943.
Ankri S, Mirelman D. Antimicrobial properties of allicin from garlic. Microbes Infect. 1999 Feb;1(2):125-9. doi: 10.1016/s1286-4579(99)80003-3.
Casella S, Leonardi M, Melai B, Fratini F, Pistelli L. The role of diallyl sulfides and dipropyl sulfides in the in vitro antimicrobial activity of the essential oil of garlic, Allium sativum L., and leek, Allium porrum L. Phytother Res. 2013 Mar;27(3):380-3. doi: 10.1002/ptr.4725.
Kahvand M, Mehran M, Haghgoo R, Faghihi T. Clinical and Radiographic Evaluation of Allium sativum Oil (Garlic Oil) in Comparison with Formocresol in Primary Molar Pulpotomy. J Int Soc Prev Community Dent. 2019 Jul 8;9(4):390-395. doi: 10.4103/jispcd.JISPCD_145_19.
Mohammad SG, Baroudi K. Assessment of the potential of Allium sativum oil as a new medicament for non-vital pulpotomy of primary teeth. J Int Soc Prev Community Dent. 2015 Jul-Aug;5(4):314-20. doi: 10.4103/2231-0762.161762.
Elheeny AAH. Allium sativum extract as an irrigant in pulpectomy of primary molars: A 12-month short-term evaluation. Clin Exp Dent Res. 2019 Jun 26;5(4):420-426. doi: 10.1002/cre2.197.
Lee HJ, Park HS, Kim KH, Kwon TY, Hong SH. Effect of garlic on bacterial biofilm formation on orthodontic wire. Angle Orthod. 2011 Sep;81(5):895-900. doi: 10.2319/121010-713.1.
Kumar A, Singh A, Dora J. Essentials perspectives for Emblica officinalis. Int J Pharm Chem Sci 2012;1(1):11-8.
Bulbule AM, Mandroli PS, Bhat KG, Bogar CM. In vitro evaluation of cytotoxicity of Emblica officinalis (amla) on cultured human primary dental pulp fibroblasts. J Indian Soc Pedod Prev Dent 2019;37(3):251-7
Bhardwaj VK. Ayurveda and holistic approach in oro-dental care: An overview. SRM J Res Dent Sci. 2015;6(3):181-6.
Tewari, S., Grover, S., Sharma, R. K., Singh, G., & Sharma, A. Emblica officinalis Irrigation as an Adjunct to Scaling and Root Planing: A Randomized Controlled Clinical Trial. J Dent Indones. 2018;25(1): 15-23.
Bansod S and Rai M. Antifungal Activity of Essential Oils from Indian Medicinal Plants against Human Pathogenic Aspergillus fumigatus and A. niger. World J. Med. Sci.,2008 ; 3 (2): 81-88.
Nadar BG, Usha GV, Lakshminarayan N. Comparative Evaluation of Efficacy of 4% Tulsi Extract (Ocimum sanctum), Fluoridated and Placebo Dentifrices against Gingivitis and Plaque among 14-15 years School Children in Davangere City, India - A Triple Blinded Randomized Clinical Trial. Contemp Clin Dent. 2020; 11(1):67-75. doi: 10.4103/ccd.ccd_109_19.
Ahirwar P, Shashikiran N D, Sundarraj RK, Singhla S, Thakur RA, Maran S. A clinical trial comparing antimicrobial efficacy of “essential oil of Ocimum sanctum” with triple antibiotic paste as an intracanal medicament in primary molars. J Indian Soc Pedod Prev Dent 2018;36:191-7
Agarwal S, Gupta S, Tandon S, Mathur R, Rai TS, Kumar M, Rathore AS. Comparative Evaluation of Ocimum sanctum and Calcium Hydroxide Mix as an Obturating Material in Deciduous Molars: An In Vivo Study. Int J Clin Pediatr Dent. 2020 Nov-Dec;13(6):617-621. doi: 10.5005/jp-journals-10005-1840.
Hugar S, M Patel P, Nagmoti J, Uppin C, Mistry L, Dhariwal N. An in vitro Comparative Evaluation of Efficacy of Disinfecting Ability of Garlic Oil, Neem Oil, Clove Oil, and Tulsi Oil with autoclaving on Endodontic K Files tested against Enterococcus faecalis. Int J Clin Pediatr Dent. 2017 Jul-Sep;10(3):283-288. doi: 10.5005/jp-journals-10005-1451.
Khurana L, Lohani S, Kumar K, Kanwar M. Triphala- Contemporary Aid in Dentistry. Int J Res Health Allied Sci 2018; 4(4):9-12.
P. K. Mukherjee et al., Iranian Journal of Pharmacology & Therapeutics., 2006;5(1):51-54.
Jagtap AG, Karkera SG. Potential of the aqueous extract of Terminalia chebula as an anticaries agent. J Ethnopharmacol. 1999 Dec 15;68(1-3):299-306. doi: 10.1016/s0378-8741(99)00058-6.
Tandon S, Gupta K, Rao S, Malagi KJ. Effect of Triphala mouthwash on the caries status. Int J Ayurveda Res. 2010 Apr;1(2):93-9. doi: 10.4103/0974-7788.64413.
Prabhakar J, Senthilkumar M, Priya MS, Mahalakshmi K, Sehgal PK, Sukumaran VG. Evaluation of antimicrobial efficacy of herbal alternatives (Triphala and green tea polyphenols), MTAD, and 5% sodium hypochlorite against Enterococcus faecalis biofilm formed on tooth substrate: an in vitro study. J Endod. 2010 Jan;36(1):83-6. doi: 10.1016/j.joen.2009.09.040.
Desai A, Anil M, Debnath S. A clinical trial to evaluate the effects of triphala as a mouthwash in comparison with chlorhexidine in chronic generalized periodontitis patient. Indian J Dent Adv. 2010;2: 243–247.
Maurya DK, Mittal N, Sharma KR, Nath G. Role of triphala in the management of peridontal disease. Anc Sci Life. 1997 Oct; 17(2):120-7. PMID: 22556832;
Kausik B, Ishita C, Ranajit KB, Uday B. Biological activities and medicinal properties of Neem (Azadirachta indica). Current Science 2002;82(11):1336-45
Ghonmode WN, Balsaraf OD, Tambe VH, Saujanya KP, Patil AK, Kakde DD. Comparison of the antibacterial efficiency of neem leaf extracts, grape seed extracts and 3% sodium hypochlorite against E. feacalis - An in vitro study. J Int Oral Health. 2013 Dec; 5(6):61-6. PMID: 24453446.
Subapriya R, Nagini S. Medicinal properties of neem leaves: a review. Curr Med Chem Anticancer Agents. 2005 Mar; 5(2):149-6. doi: 10.2174/1568011053174828.
Sorna KH, Rajasekar T, Anandhi A, Shahanas B. A Comparative study of in vitro antibacterial activity of Neem and miswak extracts against isolated cariogens from dental caries patients. J. Chem. Pharm. Res., 2011, 3(5):638-645
Bohora A, Heghe V, Kokate S. Comparison of the antibacterial efficiency of neem leaf extract and 2% sodium hypochlorite against E. faecalis, C. albicans and mixed culture - an in vitro study. Endodontology. 2010;22:8-12.
Hegde V, Kesaria DP. Comparative evaluation of antimicrobial activity of neem, propolis, turmeric, liquorice and sodium hypochlorite as root canal irrigant against E. faecalis and C. albicans - an in vitro study. Endodontology2013;25: 38-45.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
Vijayalakshmi, K., and J. Sangeetha. “Determination Of Bioactive Components Of Ethyl Acetate Fraction Of Punica Granatum Rind Extract”. International Journal of Pharmaceutical SciencesandDrugResearch,2011;3(2):pp.116-22.https://ijpsdr.com/index.php/ijpsdr/article/view/183.
Pirbalouti AG, Koohpayeh A, Karimi I. The wound healing activity of flower extracts of Punica granatum and Achillea kellalensis in Wistar rats. Acta Pol Pharm. 2010 Jan-Feb; 67(1):107-10. PMID: 20210088.
Kiany F, Niknahad H, Niknahad M. Assessing the effect of pomegranate fruit seed extract mouthwash on dental plaque and gingival inflammation. J Dent Res Rev 2016;3:117-23
Vasconcelos LC, Sampaio MC, Sampaio FC, Higino JC. Use of Punica granatum as an antifungal agent against candidiasis associated with denture stomatitis. Mycoses 2003; 46:192–96. http://dx.doi.org/10.1046/j.1439-0507.2003.00884.x
Kandra L, Gyemant G, Zajacz A, Batta G. Inhibitory effects of tannin on human salivary α-amylase. Biochem Biophys Res Commun 2004; 319:1265–71. http://dx.doi.org/10.1016/j.bbrc.2004.05.122 PMID:15194503 7.
Li Y, Wen S, Kota BP, Peng G, Li GQ, Yamahara J, Roufogalis BD. Punica granatum flower extract, a potent alpha-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats. J Ethnopharmacol. 2005 Jun 3;99(2):239-44. doi: 10.1016/j.jep.2005.02.030.
Jain N, Rajwar YC, Batra M, et al. Dentistry: Turning towards herbal Alternatives: A review. Sch J App Med Sci. 2014; 2(1C):253-7.
Lee UL, Choi SW. The Chemopreventive properties and therapeutic modulation of green tea polyphenols in Oral Squamous Cell Carcinoma. ISRN Oncol. 2011;2011:1–7.
Sagita, M. B., Turchan, A., Utomo, B., Fauzi, A. A., & Fauziah, D. (2022). Expression malondialdehyde (MDA) of brain after injury with the extract of kencur (Kaempferia Galanga L): Experimental study wistar rats. International Journal of Health & Medical Sciences, 5(1), 114-121. https://doi.org/10.21744/ijhms.v5n1.1848
Ganjre A, Kathariya R, Bagul N, et al. Anticariogenic and antibacterial properties of selected spices: Implications in oral health. Clin Nutr Res. 2015;4(4):209-15.
Ishnava KB. Role of herbal medicine in dental health. J Environ Chem Toxicol. 2018;2(1):28-9.
Scrobota I, Bolfa P, Filip AG, et al. Natural chemopreventive alternatives in oral cancer chemoprevention. J Physiol Pharmacol. 2016;67(1):161- 72
Messier C., Epifano F., Genovese S., Grenier D. Licorice and its potential beneficial effects in common oro-dental diseases. Oral Dis. 2012;18(1):32–39
Chan EW, Wong SK. Phytochemistry and pharmacology of ornamental gingers, Hedychium coronarium and Alpinia purpurata: A review. J Integr Med 2015;13:368-79.
Bode AM, Dong Z. The amazing and mighty ginger. In: Benzie IF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Ch. 7. Boca Raton, FL: CRC Press/Taylor & Francis; 2011.
Rashmi KJ, Tiwari R. Pharmacotherapeutic properties of ginger and its use in diseases of the oral cavity: A narrative review. J Adv Oral Res 2016;7(2):1-6
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