Overview on scope and advancement in regenerative medicine
Keywords:
Regenerative Medicine, Human Stem Cells, Adipose Stem Cells, Extracellular Matrix, Scaffolding Technology, ElectrospinningAbstract
Regenerative medicine is the science of replacing engineering, regenerating human cells, tissues, or organs to restore or establish normal function and has now reached its potential due to its ability to deliver cell and tissue constructs to the human body thus providing therapeutic assistance of its innate healing responses. It further comprehends the cellular and molecular differences between regenerating and non-regenerating tissues thus resulting in restoring tissue structure and function in damaged, non-regenerating tissues. Replaced or repaired tissues should be indistinguishable from normal, healthy tissues in structure and function. Cellular therapy is one such strategy wherein various cell types are isolated and used that help in understanding their mechanism of action as well as their regenerative properties when they are utilized with different biomaterials as an extracellular matrix. As scaffolds provide targeted cell growth, stem cell delivery through scaffolding technology is another regenerative therapy that is used. The process of electrospinning is used for the generation of scaffolds. Problems like the unavailability of organs for transplantation prevails and thus regenerative medicine therapy has proved to be applicable in such cases.
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