Optical coherence tomography angiography versus fluorescein angiography in diagnosis of ischemic diabetic maculopathy
Keywords:
OCT Angiography, Fluorescein Angiography, Ischemic Diabetic MaculopathyAbstract
Objectives: To compare between the use of Fundus Fluorescein Angiography (FFA) and Optical Coherence Tomography Angiography (OCTA) in the diagnosis and quantification of diabetic macular ischemia (DMI) diagnosed according to the Early Treatment Diabetic Retinopathy Study (ETDRS) classification based on Foveal avascular zone (FAZ) parameters. Patients and Methods: The presented study is a prospective randomized observer blind observational study that included 40 eyes of 25 diabetic patients who were diagnosed as having ischemic diabetic maculopathy. Diabetic patients (type 1 or type 2) having different severities of diabetic retinopathy with and without previous treatment (laser or intravitreal injections). FA and OCTA images were independently graded by 2 observers that reached agreement regarding quantitative DMI according to established protocols. Quantitative analysis of the FAZ area was performed using custom software. Results: Demographic data of the studied cases were comparable between groups. OCTA images closely correlated with FA regarding area of FAZ (mm2).
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