Microscopic study of age-related changes in germinal centre in the human appendix by using immunohistochemistry technique
Keywords:
Vermiform Appendix, Lymphatic Follicles, Germinal Centre, ImmunohistochemistryAbstract
Background: This study was conducted to observe the age-related changes in germinal centre in human appendix Subject and Methods: The study was conducted on 50 male and female appendix. All the specimens were preserved in 10% formalin solution, after paraffin processing sections were routinely stained with mouse antihuman CD 35 antibody using polymer HRP detection system using IHC technique. Results: The maximum number of lymph nodes and germinal centres found in group A (0-20yrs) and minimum found in Age group C (40-60yrs). Conclusion: Appendix play an important role in immune system.
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Rehman MM, Begum J, Khalid M, Latif SA, Nessa A, Jahan MK, Shafiquzzaman M, Parvin B, Akhunda AK. Histomorphological study of lymphoid follicle of vermiform appendix. Mymensingh Med J, 2008 July; 17(2): 134-40. 9 9.
E L Rabotnikova. Endocrinocytes of the appendix in the human fetus Arkh Anat Gistol Embriol1988 Aug;95(8):78-81
I.A. kooji, S. Sahami, S. L. Meijer. The immunology of the vermiform appendix: a review of the literature. Clin Exp Immunol. 2016 Oct; 186(1): 1–9.
Niazi SH. Histomorphometric study of vermiform appendix. Professional Med J 2019; 26(10):1635-1639. DOI: 10.29309/TPMJ/2019.26.10.29194.
Stein H, Gerdes J, Mason DY The normal and malignant germinal centre. Clin Haematol, (1982) 11: 531 -559.
Bakar SM, Shamim M, Salam A, Sultana SA. Microscopic studies on postmortem appendix of the adult males of Bangladesh. Irish Journal of Medical Sciences, 2015; 185(1): 249-57. 10.
Suganthy Rabi, Inbam Indrasingh Follicular dendritic cells in normal and infected human appendix Eur. J. Anat. (2017) 21 (1): 31-35
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949.
Klaus GG, Humphrey JH. The generation of memory cells. I. The role of C3 in the generation of B memory cells. Immunology (1977), 33: 31-40.
Butcher EC, Rouse RY, Coffman RL, Nottenburg CN, Hardy RR, Weissman IL. Surface phenotype of Peyer’s patch germinal center cells: implications for the role of germinal centers in B cell differentiation. J Immunol Baltim Md, (1982) 129: 2698-2707.
Heinen E, Tsunoda T, Marcoty C, Bosseloir A, Kinet-Denoël C, Antoine N, Simar LJ (1991) The germinal centre: a monastery or a bar? Res Immunol, 142: 242-244.
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