Microscopic study of age-related changes in germinal centre in the human appendix by using immunohistochemistry technique
Keywords:
Vermiform Appendix, Lymphatic Follicles, Germinal Centre, ImmunohistochemistryAbstract
Background: This study was conducted to observe the age-related changes in germinal centre in human appendix Subject and Methods: The study was conducted on 50 male and female appendix. All the specimens were preserved in 10% formalin solution, after paraffin processing sections were routinely stained with mouse antihuman CD 35 antibody using polymer HRP detection system using IHC technique. Results: The maximum number of lymph nodes and germinal centres found in group A (0-20yrs) and minimum found in Age group C (40-60yrs). Conclusion: Appendix play an important role in immune system.
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