Effect of x- ray on the treatment of breast cancer combined with amygdalin and doxorubicin separately

Mustafa I. Ahmed Aldulaimy; Numan S. Dawood; Amera Mahmood M. Al-Rawi

doi:10.53730/ijhs.v6nS5.11977

Authors

Mustafa I. Ahmed Aldulaimy Department of physiology, College of Medicine, University of Baghdad, Baghdad, Iraq
Numan S. Dawood
numans@comed.uobaghdad.edu.iq
Department of physiology, College of Medicine, University of Baghdad, Baghdad, Iraq
Amera Mahmood M. Al-Rawi Department of Biology, College of Sciences, University of Mosul, Iraq

Keywords:

Radiotherapy, x-ray, MCF-7, Amygdalin, Doxorubicin

Abstract

Background: Radiation therapy has the ability to destroy healthy cells in addition to cancer cells in the area being treated. However, when radiation combines with doxorubicin, it becomes more effective on breast cancer treatment. Objective: This study aims to clarify the effect of X-ray from LINAC combined with amygdalin and doxorubicin on breast cancer treatment, and the possibility of using amygdalin with X-ray instead of doxorubicin for the breast cancer treatment. Method: Two cell lines were used in this study, the first one was MCF-7 cell line and second one was WRL- 68 normal cell line. These cells were preserved in liquid nitrogen, prepared, developed and tested in the (place). The effect of three x-ray doses combined with amygdalin and with doxorubicin was studied on these strains. Results: Combination of radiation with amygdalin and with doxorubicin, separately, exam revealed no statistically significant difference between x-rays doses (1Gy, 3Gy and 5 Gy) combined with amygdalin and x-rays doses (1Gy, 3Gy and 5 Gy) combined with doxorubicin for MCF-7 and WRL-68.In conclusion: there is possible to be considered amygdalin as a promise breast cancer treatment instead of doxorubicin combined with x-ray.

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