Evaluation of salivary alpha-amylase level in patients undergoing surgical extraction of impacted lower wisdom teeth
Keywords:
Salivary alpha amylase, impacted third molar, salivary enzymes, inflammatory markers, salivary biomarkerAbstract
Objectives: to evaluate changes in the level of salivary alpha amylase following surgical removal of impacted lower wisdom teeth. Methodology: this is a prospective cohort study, which included patients submitted for surgical extraction of impacted lower wisdom teeth, three samples of saliva were taken from each patient (preoperative, 48 hours, and 7 days postoperatively). The concentration of salivary amylase is assessed using Enzyme Linked Immunosorbent Assay (ELISA) kit, the difference between salivary amylase level pre- and postoperatively were assessed and correlated with the variables which are age, gender and side of impaction. Results: 36 impacted lower wisdom teeth were removed from 34 patients (19 females 55.88%, and 15 males 44.12%) with mean age of 24.85 years and a standard deviation of 4.93 years, 19 impacted lower wisdom teeth were in the right side (53%) and 17 (47%) were in the left side. The mean ± SD of preoperative salivary amylase concentration was 126.2 ± 31.97, 48 hours postoperatively it was 131.8 ± 48.99, and 7 days postoperatively it was 127.0 ± 32.09. The difference between pre- and postoperative salivary amylase level was non-significant. Conclusion: salivary alpha amylase level rises but non-significantly after surgical removal of impacted lower wisdom teeth.
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