Pharmacological treatment of acute Gout attacks
Which treatment is effective? Review the latest systematic reviews using the AMSTAR tool
Keywords:
pharmacological, gout attacks, treatment, AMSTAR toolAbstract
Gout is an inflammatory condition of the joints caused by deposition of crystallized monosodium urate (MSU) in the joint which leads to Arthritis. there are many debates about the suitable pharmacological therapy for the acute inflammatory gout attacks. The Pharmacological treatment included colchicine, non steroidal anti- inflammatory (NASIDS) and corticosteroid injection. The aim of this study is to review the evidences which studied the effect of Colchicine, NASID and corticosteroid injections and discuss their effectiveness in treating the acute flares of Gout. After evaluation the validity of the latest best evidences presented in the database by using the AMSTAR tool. There was no best drug and no optimal dose identified in treating acute Gout attacks. Doctors should be careful in selecting the treatment considering the side effect of each medication and deal with each patient individually to provide the best health care.
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References
Dalbeth N, Lauterio TJ, Wolfe HR. Mechanism of action of colchicine in the treatment of gout. Clin Ther [Internet]. 2014;36(10):1465–79. Available from: http://dx.doi.org/10.1016/j.clinthera.2014.07.017
Diniari, N. K. S., & Aryani, L. N. A. (2022). Characteristics and pharmacological treatment options of delirium patients treated at Sanglah Central General Hospital . International Journal of Health & Medical Sciences, 5(1), 37-43. https://doi.org/10.21744/ijhms.v5n1.1835
Hitzeman N, Stephens R. Colchicine for acute gout. Am Fam Physician. 2015;91(11):759–60.
Khanna PP, Gladue HS, Singh MK, FitzGerald JD, Bae S, Prakash S, et al. Treatment of acute gout: A systematic review. Semin Arthritis Rheum. 2014;44(1):31–8.
Lee BH, Yang JH, Lee HM, Park JY, Park SE, Moon SH. Surgical outcome predictor in degenerative lumbar spinal disease based on health related quality of life using euro-quality 5 dimensions analysis. Yonsei Med J. 2016;57(5):1214–21.
Li Q, Li X, Wang J, Liu H, Kwong JS, Chen H, et al. Diagnosis and treatment for hyperuricemia and gout : a systematic review of clinical practice guidelines and consensus statements. 2019;1–13.
Richette P, Bardin T. Colchicine for the treatment of gout. Expert Opin Pharmacother. 2010;11(17):2933–8.
Shekelle PG, Newberry SJ, FitzGerald JD, Motala A, O’Hanlon CE, Tariq A, et al. Management of gout: A systematic review in support of an American college of physicians clinical practice guideline. Ann Intern Med. 2017;166(1):37–51.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
Tang H, Xu G, Zheng Q, Cheng Y, Zheng H, Li J, et al. Treatment for acute flares of gout. Medicine (Baltimore). 2020;99(14):e19668.
van Durme CMPG, Wechalekar MD, Buchbinder R, Schlesinger N, van der Heijde D, Landewé RBM. Non-steroidal anti-inflammatory drugs for acute gout. Cochrane Database Syst Rev. 2014;2014(9).
Vargas-Santos AB, Neogi T. Management of Gout and Hyperuricemia in CKD. Am J Kidney Dis [Internet]. 2017;70(3):422–39. Available from: http://dx.doi.org/10.1053/j.ajkd.2017.01.055
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