Evaluating the role of dates compound in iron deficiency anemia in children

https://doi.org/10.53730/ijhs.v6nS4.12239

Authors

  • Rahul Gujarathi Professor, Department of Pediatrics, Bharati Vidyapeeth (Deemed to be University), College of Ayurved, Katraj, Pune, India
  • Manish Arora Professor, Department of Preventive and Social Medicine, Government Ayurveda College, Ajwa Road, Vadodara, Gujarat, India
  • Mrudula Kulkarni Associate Professor, Department of Gynecology and Obstetrics, Bharati Vidyapeeth (Deemed to be University), College of Ayurved, Katraj, Pune, India
  • Ravindra Patwardhan Professor, Department of Preventive and Social medicine, Bharati Vidyapeeth (Deemed to be University), College of Ayurved, Katraj, Pune, India
  • Sarita Kapgate Associate Professor, Department of Toxicology and Forensic Medicine, (Bharati Vidyapeeth Deemed to be University), College of Ayurved,Katraj, Pune, India

Keywords:

iron deficiency anemia (IDA), bio-iron, dates, black currant, hemoglobin, serum iron

Abstract

Iron deficiency is by far the first cause of nutritional anemia worldwide. A large portion of iron deficiency is preventable with appropriate and timely intervention. Anemia has been a prevalent health issue in India with over 70% children. Nearly 73 million children below the age of three (79%) suffer from varying degrees of anemia. ṇḍu, in Āyurveda, is supposed to be the nearest co-related entity to anemia. Iron deficiency is usually the result of inadequate bioavailable dietary iron, increased iron requirement during rapid growth, and increased blood loss for any reason. If not corrected, iron deficiency leads to anemia and cognitive impairment, decreased physical capacity, and reduced immunity. The effects of anemia on children are the direst because their bodies are still developing. The management of this syndrome is supplementing elemental iron or bio-iron through food or as medicine. Elemental iron supplements have their own drawbacks as unwarranted effects like constipation, vomiting, metallic taste, non-acceptance and compliance, iron deposition in the tissues and sometimes iron toxicity. Bio-organic iron of natural origin (plant and animal origin) bypasses these symptoms, it is readily absorbed and readily bio-converted. 

Downloads

Download data is not yet available.

References

"Soil-transmitted helminthic infections". Archived from the original on 2014-02-21. Retrieved 2014-03-05. World Health Organization Fact Sheet No. 366, Soil Transmitted Helminthic Infections, updated June 2013

Abdulameer, S. jasim, & Jaber, A. H. A. (2022). Cytogenetic study of types anemia patients. International Journal of Health Sciences, 6(S7), 487–499. https://doi.org/10.53730/ijhs.v6n7.11090

Abdullah K, Birken CS, Maguire JL, et al. Re-evaluation of serum ferritin cut-off values for the diagnosis of iron deficiency in children aged 12-36 months. J Pediatr .2017;188:287–290

Agniveśa in Caraka Saṁhitā revised by Caraka and Dṛḍhbala with Āyurveda Dīpikā Commentry of Cakrapāṇidatta, ed. Jadavji Trikamji Acharya, Cikitsāsthāna 16/40-43.MunshiramMohanlal Publishers Pvt. Ltd., Mumbai. pp 528

Berglund SK, Westrup B, Domellöf M. Iron supplementation until 6 months protects marginally low-birth-weight infants from iron deficiency during their first year of life. J Pediatr Gastroenterol Nutr. 2015;60(3):390–395

Centre for Disease Control Prevention (CDC) (October 11, 2002). "Iron Deficiency – United States, 1999–2000". MMWR. 51 (40): 897–899. PMID 12418542. Archived from the original on May 5, 2012. Retrieved April 21, 2021

Congdon EL, Westerlund A, Algarin C, et al. Iron deficiency in infancy is associated with altered neural correlates of recognition memory at 10 years. J Pediatr. 2012;160:1027– 1033

DeLoughery TG. Microcytic anaemia. N Engl J Med. 2014;371:1324–1331

Falkingham M, Abdelhamid A, Curtis P, et al. The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis. Nutr J. 2010;9:4

Ferrara M, Capozzi L, Russo R, et al. Reliability of red blood cell indices and formulas to discriminate between beta thalassemia trait and iron deficiency in children. Haematology. 2010;15(2):112–115

Fu-Ping Lai, Yao-Jong Yang. The prevalence and characteristics of cow's milk protein allergy in infants and young children with iron deficiency anaemia Pediatr Neonatol. 2018 Feb; 59(1):48-52. doi: 10.1016/j.pedneo.2017.01.004. E pub 2017 Jun 30.

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. October 2016. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282

Hanin Ghrayeb, Mazen Elias, JeriesNashashibi, Awni Youssef, Mari Manal, LialaMahagna, MasalhaRefaat, Naama Schwartz, Adi Elias. Appetite and ghrelin levels in iron deficiency anaemia and the effect of parenteral iron therapy: A longitudinal study. PLoS One. 2020; 15(6): e0234209. Published online 2020. doi: 10.1371/journal.pone.0234209 PMCID: PMC7272047 PMID: 32497136.

http://namstp.ayush.gov.in/ accessed on 23.06.2022

ICMR-National Institute of Nutrition. In Nutritive Value of Indian Foods (NVIF).

Iriti M, Faoro F. 2006. Grape phytochemicals: A bouquet of old and new nutraceuticals for human health. Med Hypothesis 67: 833–838

Jeong WS, Lachance PA. Phytosterols and fatty acids in fig (Ficus carica var. mission) fruit and tree components. Food Chemistry and Toxicology. 2001; 66:278– 281.

Kaushansky K, KippsTJ. Haematopoietic agents: growth factors, minerals, and vitamins. In: Brunton LL, Chabner BA, Knollmann BC, ed. Goodman and Gilman’s The pharmacological basis of therapeutics. 12thed. USA: McGraw Hill; 2011: 1076-85.

L. S. Valberg, K. B. Taylor and L. J. Witts, “The effect of iron deficiency on the

stomach of the rat” Bd. J. Nut. (1961), 15, 473-80.

Longo, Dan L.; Camaschella, Clara (7 May 2015). "Iron-Deficiency Anaemia". New England Journal of Medicine. 372 (19): 1832–1843. doi:10.1056/NEJMra1401038. PMID 25946282

Mādhavakara in Mādhava Nidāna with Madhukoṣa commentary by Vijayarakśita and Śrikaṇṭhadatta. ed. Jadavji Trikmji Acharya. 8/1. Nirnay Sagar Press, Mumbai. pp 95

McDonagh MS, Blazina I, Dana T, et al. screening and routine supplementation for iron deficiency anaemia: a systematic review. Paediatrics. 2015;135(4):723–733

Peyrin-Biroulet, Laurent; Williet, Nicolas; Cacoub, Patrice (December 1, 2015). "Guidelines on the diagnosis and treatment of iron deficiency across indications: a systematic review". The American Journal of Clinical Nutrition. 102 (6): 1585–1594. doi:10.3945/ajcn.114.103366. PMID 26561626

Powers JM, Buchanan GR. Diagnosis and management of iron deficiency anaemia. Hematol Oncol Clin North Am. 2014;28(4):729–74

Powers JM, Buchanan GR. Potential for improved screening, diagnosis and treatment for iron deficiency and iron deficiency anaemia in young children. J Pediatr. 2017;188:8– 10

Shah RH, Meti Rajneesh, Arora MT, Gujarathi Rahul. Anjīra (Ficus carica L) – A food supplement with medicinal benefits. International Journal of Green Pharmacy. Oct-Dec 2020; 14(4):343-347

Shah RH, Pani Sudhirkumar, Arora MT, Gujarathi Rahul. Kharjoor (dates fruit)-an alternative balanced nutritional diet with medicinal benefits. Bulletin of Environment, Pharmacology and Life Sciences. 2022; 11

Slatnar A, Klancar U, Stampar F, Veberic R. Effect of drying of figs (Ficus carica L.) on the contents of sugars, organic acids, and phenolic compounds. Journal of Agricultural and Food Chemistry. 2011; 59(21):11696–11702

Smith RE (March 2010). "The clinical and economic burden of anaemia". The American Journal of Managed Care. 16 Suppl Issues: S59–66. PMID 20297873

Solomon A, Golubowicz S, Yablowicz Z, et al. Antioxidant activities and anthocyanin content of fresh fruits of common fig (Ficus carica L.) Journal of Agricultural and Food Chemistry. 2006; 54(20):7717–7723

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864

Suryatika, I. B. M., Anggarani, N. K. N., Poniman, S., & Sutapa, G. N. (2020). Potential risk of cancer in body organs as result of torak CT-scan exposure. International Journal of Physical Sciences and Engineering, 4(3), 1–6. https://doi.org/10.29332/ijpse.v4n3.465

Suśruta in Suśruta Saṁhitā with Nibandhsaṅgraha commentary of Dalhaṇa, ed. Jadavji Trikamji Acharya, Uttarataṅtra 44/3. Chaukhamba Surabharati Prakashan, Varanasi. pp 621

Upanandan Mandal, Kazi Monjur Ali, Kausik Chatterjee, Debasis De, Anjan

Biswas, and Debidas Ghosh. Management of experimental hypochlorhydria with iron deficiency by the composite extract of Fumaria vaillantii L. and Benincasa hispida T. in rat. J Nat Sci Biol Med. 2014 Jul-Dec; 5(2): 397–403. doi: 10.4103/0976-9668.136202 PMCID: PMC4121923 PMID: 25097423.

Vāgbhaṭa in Aṣṭāṅga Hṛdaya. ed. Gadre GK. Sārtha Vāgbhaṭa Nidānasthāna 13/3. Published Ramesh Vitthal Raghuvanshi, Gajanan Book Depot, Mumbai. pp 200

Veberic R, Colaric M, Stampar F. Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern Mediterranean region. Food Chemistry. 2008; 106(1):153– 157

Veberic R, Jakopic J, Stampar F. Internal fruit quality of figs (Ficus carica L.) in the Northern Mediterranean Region. Italian Journal of Food Science. 2008; 20(2):255– 262

Vinson JA, Zubik L, Bose P, Samman N, Proch J. Dried fruits: excellent in vitro and in vivo antioxidants. Journal of the American College of Nutrition. 2005; 24(1):44–50

Vinson JA. The functional food properties of figs. Cereal Foods World. 1999; 44(2):82–87

Zimmermann MB, Hurrell RF: Nutritional iron deficiency, Lancet 370:511–520, 200

Published

31-08-2022

How to Cite

Gujarathi, R., Arora, M., Kulkarni, M., Patwardhan, R., & Kapgate, S. (2022). Evaluating the role of dates compound in iron deficiency anemia in children. International Journal of Health Sciences, 6(S4), 12663–12675. https://doi.org/10.53730/ijhs.v6nS4.12239

Issue

Section

Peer Review Articles