Management of early complications of hepatic artery post living donor liver transplantations in adults

Hussien Kamal Eldin Hussein; Mostafa A. EL-Shazly; Omar A. EL-Azeez; Karim Adel Hosny; Alaa Eldin Mahmoud Amin; Mamdouh Ab  El Salam Mabrouk

doi:10.53730/ijhs.v6nS9.12240

Authors

Hussien Kamal Eldin Hussein Professor of General & Vascular Surgery, Faculty of Medicine – Cairo University
Mostafa A. EL-Shazly Professor of General & Hepatobiliary Surgery, Faculty of Medicine – Cairo University, Egypt
Omar A. EL-Azeez Professor of Radiodiagnosis, Faculty of Medicine –Cairo University, Egypt
Karim Adel Hosny Professor of General & Vascular Surgery, Faculty of Medicine – Cairo University, Egypt
Alaa Eldin Mahmoud Amin
alaa301089@cu.edu.eg
Lecturer of Vascular Surgery, Faculty of Medicine – Cairo University, Egypt
Mamdouh Ab El Salam Mabrouk M.B., B.Ch., M.Sc.

Keywords:

early complications, hepatic artery, liver transplantations

Abstract

Background: Liver transplantation has rightly gained recognition as an established therapy for end stage liver disease and acute liver failure. Liver transplantation in humans has come a very long way in a short period of time. The aim were to identify the causes and the risk factors of early complications of hepatic artery post LDLT in adults. Methods: This is a retrospective & prospective analysis study, which was carried out in Orthopedic Surgery This study was conducted on a retrospective review of 20 recipient patients who underwent LDLT and suffering from an early hepatic artery complications at Cairo University Hospitals and Dar Al Foad Hospital from starting the program till 2016. Results. Risk factors were examined as predictors of success including age, sex, history of HCV +/- HCC and any co-morbidity (DM, HTN), the Child-Pugh score, MELD score, identification of potential risk factors (trans-arterial chemo embolization (TACE) & Hyper-coaglable states), careful preoperative evaluations (Donor & Recipient). Conclusion: Early HA complications remain a major cause of morbidity and mortality after LDLT. Urgent revascularization is necessary to avoid graft loss.

Downloads

Download data is not yet available.

References

Abdeldayem H, Allam N et al. Living Donor Liver Transplantation on Liver Transplantation Technical Issues and Complications. Janeza Trdine 9, 51000 Rijeka, Croatia, February, 2012 InTech: 1-100.

Abdeldayem H, Allam N, Adawy N, Salah E, Aziz A, Kashkoush S, Gad H, Helmy A. Moral and Ethical Issues in Liver Transplantation in Egypt. Exp Clin Transplant. 2009; 1: 18-24.

Almogy G, Bloom A, Verstandig A, Eid A. Hepatic artery pseudo-aneurysm after liver transplantation. A result of transhepatic biliary drainage for primary sclerosing cholangitis.Transpl Int 2002; 15: 53-55

Amesur NB, Zajko AB. Interventional radiology in liver transplantation. Liver Transpl 2006; 12: 330-351.

Amin A, Kamel R, Hatata Y, et al. Crucial issues of hepatic artery reconstruction in living donor liver transplantation: our experience with 133 cases at Dar El-Fouad hospital, Egypt. J Reconstr Microsurg 2009;

Bekker J, Ploem S, de Jong KP. Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors. Am J Transpl, 9: 746, 200.

Burra P, Germani G, Gnoato F, Lazarro S, Russo FP, Cillo U, Senzolo M. Adherence in liver transplant recipients. Liver Transpl. 2011; 17(7): 760–70.

Cobeña-Morante, G. K., & Bran-Cepeda, H. C. (2022). Oral language difficulties in patients aged 4 to 7 years at the chone type C health center. International Journal of Social Sciences and Humanities, 6(2), 142–150. https://doi.org/10.53730/ijssh.v6n2.10322

Duffy JP, Hong JC, Farmer GE, et al. Vascular complications of orthotopic liver transplantation: experience in more than 4200 patients. J Am Coll Surg 2009; 208: 896.

Gordon SA, Carmody IC, Busuttil, R., & Klintmalm, G et al. Arterial Complications After Liver Transplantation. In: Transplantation of the Liver, Busuttil and Klintmalm, (Editors), pp. (2005). 575-588, Elsevier Saunders, ISBN 0-7216-01118-9, Philadelphia, PA, USA.

Haberal M, Karakayali H, Atiq A, Sevmis S, Moray G, Ozcay F, Boyvat F. Duct-to-duct biliary reconstruction without a stent in pediatric living-donor liver transplantation. Transplant Proc., 2011; 43(2): 595-7.

Kayahan EM, Coskun M, Ozbek O, et al. Accuracy of multidetector computed tomographic angiography for detecting hepatic artery complications after liver transplantation. Transplant Proc 2007; 39: 3239.

Nishida S, Kato T, Levi D, et al. Effect of protocol Doppler ultrasonography and urgent revascularization on early hepatic artery thrombosis after paediatric liver transplantation. Arch Surg 2002; 137: 1279.

Nolten A, Sproat I. Hepatic artery thrombosis after liver transplantation: temporal accuracy of diagnosis with duplex US and the syndrome of impending thrombosis. Radiology 1996; 198: 553.

Pareja E, Cortes M, Navarro R, et al. Vascular Complications After Orthotopic Liver Transplantation: (Hepatic Artery Thrombosis). Transplantation Proceedings, 42, (2970–2972). Elsevier Inc., 2010.

Proposito D, Loinaz Segurola C, Garcia Garcı`a I, et al. Assessment of risk factors in the incidence of hepatic artery thrombosis in a consecutive series of 687 liver transplantations. Ann Ital Chir 2001; 72: 187.

Rashid T, Alexander E, James N et al. General Considerations on Liver Transplantation Clinical Assessment and Management. British Library. January 2014: 1- 20.

Singhal A, Stokes K, Sebastian A, et al. Endovascular treatment of hepatic artery thrombosis following liver transplantation. Transpl Int 2010; 23: 245.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938

Thomas E. Starzl, James N et al. Introduction on Liver Transplantation Clinical Assessment and Management British Library. January 2014: 1-20.

Tilyakov, H. A., Valiyev, E. Y., Tilyakov, A. B., & Tilyakov, A. B. (2021). A new approach to surgical treatment of victims with pelvic and femoral fracture injuries, taking into account the severity of the condition and the severity of the injury. International Journal of Health & Medical Sciences, 4(3), 338-346. https://doi.org/10.31295/ijhms.v4n3.1763

Wakiya T, Sanad Y, et al. Endovascular interventions for hepatic artery complications immediately after pediatric liver transplantation. European Society for Organ Transplantation 24 (2011) 984–990.

Warnaar N, Polak WG, de Jong KP, et al. Long-term results of urgent revascularization for hepatic artery thrombosis after pediatric liver transplantation. Liver Transpl 2010; 16: 847.