Positive correlation between parathyroid hormone-related protein (PTHrP) and vitamin D bind protein (VDBP) in osteoporosis and osteopenia patients in AL-Najaf city /Iraq

Zahraa K. Abbas; Furqan Moein Auda; Jawad K. Abbas; Basim M. Ali

doi:10.53730/ijhs.v6nS6.12255

Authors

Zahraa K. Abbas Department of Chemistry, College of Science, Kufa University, Iraq
Furqan Moein Auda
furqan.chmala@uokufa.edu.iq
Department of Chemistry, College of Science, Kufa University, Iraq
Jawad K. Abbas Department of Chemistry, College of Science, Kufa University, Iraq
Basim M. Ali Department of Chemistry, College of Science, Kufa University, Iraq

Keywords:

parathyroid hormone, parathyroid hormone-related protein, osteoporosis, osteopenia, T-score, vitamin D and vitamin D binding protein

Abstract

Severe and moderate osteoporosis is a common disease in the world. It is considered a silent disease that has no clear signs. The current study aimed to evaluate the correlation between Parathyroid Hormone-related Protein (PTHrP) with Vitamin D Bind protein(VDBP) in Osteoporosis and Osteopenia patients in AL-Najaf city /Iraq. To succeed in the desired goal, 100 patients (50 with Osteopenia and 50 with Osteoporosis) participated in this study, on the other hand, fifty healthy individuals were selected as a control group. Serum Parathyroid hormone-related protein (PTHrP), Parathyroid hormone (PTH), Vitamin D Bind protein (VDBP) and Vitamin D were evaluated using the Elisa technique. The study was unique in proving a Positive correlation between parathyroid hormone-related protein and Vitamin D Bind protein in Osteoporosis and Osteopenia patients. inverse correlation between parathyroid hormone and T-score. In addition, the results indicated that there was a significant decrease in the levels of Parathyroid hormone (PTH), Parathyroid hormone-related protein (PTHrP), Vitamin D and Vitamin D Bind protein (VDBP) in patients compared to the control group.

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