The Bethesda system of reporting cytopathology of thyroid nodules in correlation with radiological and clinicopathological findings
Keywords:
Bethesda system, cytopathology, thyroid nodules, radiological, clinicopathological findingsAbstract
Background: Thyroid nodules are common, affecting up to 76% of the population. One in every two patients with ultrasonography has a thyroid nodule. Aim of the study: To reporting cytopathological study of thyroid FNA nodules and to correlate it with radiological findings and to compare patient characteristics in low and high-risk groups. Materials and Methods: A retrospective study included FNA cytology of 100 patients with a total of 103 thyroid nodules. Slides were retrieved and reviewed, and Bethesda categories were recorded. Ultrasound reports with TIRADS classification and patients’ demographics were retrieved from archived patient notes. The data were tabulated and analyzed. Results: Most nodules were classified as low or moderately suspicious (TIRADS 2 and 3), with only 4 (3.8%) classified as very suspicious (TIRADS 5). Benign (Bethesda II) was reported in 52 (50.5%), follicular neoplasm (Bethesda IV) in 7 (6.8%), and papillary carcinoma (Bethesda V) in 3 (2.9%) of FNA assessed nodules. TIRADS 5 and cytological impressions agreed perfectly. TIRADS 1&2 and cytological impressions also agreed well. Conclusion: TIRADS improves thyroid carcinoma diagnosis and avoids needless interventions. The strong concordance of TIRADS II with Bethesda II demonstrates its reliability in detecting nodules that do not require FNA or further study.
Downloads
References
Abdella M R , Al-Ahmer M, Khidr H. Recurrent nodular goiter: Predictors of recurrence and outcome after reoperation. AL- AZHAR ASSIUT MEDICAL JOURNAL. 2014;12(1).
Afroze N, Kayani N, Hasan SH. Role of fine needle aspiration cytology in the diagnosis of palpable thyroid lesions. Indian J Pathol Microbiol. 2002;45(3):241-6.
AL-Hamadani , D.A. Evaluation of thyroid Nodules by the Bethesda system for Reporting Thyroid cytolopathology (TBSRTC). Thesis, scientific council of pathology, Traqi commission for Medical Specialization. Baghdad 2020.
Bancroft JD, Cook HC. Manual of Histological Techniques and Their Diagnostic Application: Churchill Livingstone; 1994.
Cibas ES, Ali SZ. The 2017 Bethesda System for Reporting Thyroid Cytopathology. Thyroid : official journal of the American Thyroid Association. 2017;27(11):1341-6.
Cibas ES, Ali SZ. The 2017 Bethesda System for Reporting Thyroid Cytopathology. J Am Soc Cytopathol. 2017;6(6):217-22.
Ding X, Xu Y, Wang Y, Li X, Lu C, Su J, et al. Gender Disparity in the Relationship between Prevalence of Thyroid Nodules and Metabolic Syndrome Components: The SHDC-CDPC Community-Based Study. Mediators of inflammation. 2017;2017:8481049-.
Durante C, Grani G, Lamartina L, Filetti S, Mandel SJ, Cooper DS. The Diagnosis and Management of Thyroid Nodules: A Review. Jama. 2018;319(9):914-24.
Figge JJ. Epidemiology of Thyroid Cancer. In: Wartofsky L. VND, editor. Thyroid Cancer: Humana Press; 2006.
Gharib H, Papini E, Garber JR, Duick DS, Harrell RM, Hegedüs L, et al. American Association of Clinical Endocrinologists, American College Of Endocrinology, and Associazione Medici Endocrinologi Medical Guidelines For Clinical Practice For The Diagnosis And Management Of Thyroid Nodules--2016 Update. Endocr Pract. 2016;22(5):622-39.
Grani G, Lamartina L, Ascoli V, Bosco D, Biffoni M, Giacomelli L, et al. Reducing the Number of Unnecessary Thyroid Biopsies While Improving Diagnostic Accuracy: Toward the "Right" TIRADS. The Journal of clinical endocrinology and metabolism. 2019;104(1):95-102.
Ha EJ, Na DG, Baek JH, Sung JY, Kim JH, Kang SY. US Fine-Needle Aspiration Biopsy for Thyroid Malignancy: Diagnostic Performance of Seven Society Guidelines Applied to 2000 Thyroid Nodules. Radiology. 2018;287(3):893-900.
Hussain AM, Lafta RK. Cancer Trends in Iraq 2000-2016. Oman medical journal. 2021;36(1):e219-e.
Kamaluddin. (2021). Government and Private Collaboration in Coping with Covid-19 in Sorong City. International Research Journal of Management, IT and Social Sciences, 8(5), 333-341. https://doi.org/10.21744/irjmis.v8n5.1907
Khaleel Ibraheem Mohson, Hiba Mohammed, Kamal A. Grayscale ultrasound and strain elastography in the characterization of thyroid nodule in correlation with fine-needle aspiration cytology. Int J Radiol Diagn Imaging 2021;4(1):3.
Martini, I. A. O., Lasmi, N. W., Jaya, N., & Sutrisni, N. K. E. (2017). Improving cooperative performance through human resource development efforts. International Journal of Social Sciences and Humanities, 1(3), 49–58. https://doi.org/10.29332/ijssh.v1n3.55
Mettler J, Armefti S, Schmidt M, Faust M, Engels M, Chiapponi C. Benign Thyroid Diseases: Are There Gender-Specific Differences for Diagnosis and Treatment of Nontoxic Thyroid Nodules? Results from a 4-Year Retrospective Analysis of an Endocrine Tumor Board. Visceral Medicine. 2020;36(1):28-33.
Mohammud Habash M. Prevalence of Thyroid Defects in Diyala, Iraq. Medico Legal Update. 2021;21(3):408-15.
Osuch JR, Reeves MJ, Pathak DR, Kinchelow T. BREASTAID: Clinical results from early development of a clinical decision rule for palpable solid breast masses. Annals of surgery. 2003;238(5):728-37.
Safavi A, Azizi F, Jafari R, Chaibakhsh S, Safavi AA. Thyroid Cancer Epidemiology in Iran: a Time Trend Study. Asian Pacific journal of cancer prevention : APJCP. 2016;17(1):407-12.
Seib CD, Sosa JA. Evolving Understanding of the Epidemiology of Thyroid Cancer. Endocrinology and metabolism clinics of North America. 2019;48(1):23-35.
Sharkas GF, Tarawneh MR, Arqoub KH, Nimri OF, Al Zughul MJ. Epidemiology of thyroid cancer in Jordan from 1996 to 2008. 2011.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
Tessler FN, Middleton WD, Grant EG, Hoang JK, Berland LL, Teefey SA, et al. ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee. Journal of the American College of Radiology : JACR. 2017;14(5):587-95.
Uyar O, Cetin B, Aksel B, Dogan L, Beksac K, Akgul GG, et al. Malignancy in Solitary Thyroid Nodules: Evaluation of Risk Factors. Oncology Research and Treatment. 2017;40(6):360-3.
Wu HH, Swadley MJ. The Bethesda system for reporting thyroid cytopathology: into the clinic. Pathol Lab Med Int. 2015;7:47.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








