Estimation of some biomarkers in obese men and their adoption as early risk predictors of metabolic syndrome
Keywords:
Adiponectin, IL-6, IGF-1, MCP-1, Metabolic syndrome, ObesityAbstract
This study aimed to estimate the levels of the biomarkers ADP, IL-6, IGF-1 and MCP-1 in the serum of obese men and adopt them as early predictors of the occurrence of metabolic syndrome. A total of (88) samples from men, (and 60) samples from obese men, were divided according to body mass index (BMI) and waist circumference (WC) into two groups. The first group had BMI values between 35-40 kg/m2 and WC 110-125 cm., while the 2nd group had BMI >40 kg/m2 and WC >125 cm. A (28) samples were collected from healthy, with BMI values between 18.5-24.5 kg/m2 and WC was < 102 cm. The results show that there is a significant increase level IL-6 at P ≤ 0.01 in the obese group compared with the healthy, and it was significantly higher in the group with WC > 125 cm. There was a significant decrease in the concentration biomarker IGF-1 in the obesity group, and it was significantly higher in the BMI ≥40 and WC 110-125 cm groups.
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