The effect of alcoholic and aqueous extract of Capparis spinosa leaves on histological and physiological structure in the kidneys of male rats injected with lead acetate intraperitoneally

Omar Khamis Jaber; Loay H. Ali; Haitham Latif Abdel Hadi

doi:10.53730/ijhs.v6nS6.12586

Authors

Omar Khamis Jaber
Ome20u1009@uoanbar.edu.iq
Department of Biology, College of Education for Pure Sciences, University of Anbar, Ramadi, Iraq
Loay H. Ali Department of Biology, College of Education for Pure Sciences, University of Anbar, Ramadi, Iraq
Haitham Latif Abdel Hadi Department of Biology, College of Education for Pure Sciences, University of Anbar, Ramadi, Iraq

Keywords:

lead acetate, kidney, urea, creatinine, glutathione, capers

Abstract

The current study aimed to investigate the curative and preventive effect of alcoholic and aqueous extract of Capparis spinosa leaves on the histological structure of the kidneys and some biochemical parameters of male rats injected intraperitoneally with lead acetate. Biometrics included urea, creatinine, uric acid and total protein levels and total antioxidants (T-AOX), glutathione (GSH) and malondial aldehyde (MDA) assay. The study included 40 male laboratory male albino rats of the Sprague dawley breed, with weights ranging between 170-200 grams, and they were randomly divided into eight groups. The second group injected intraperitoneally with lead acetate, the third group was injected with the alcoholic extract of capers leaves, the fourth group was injected with aqueous extract of capers leaves, the fifth group was injected with britonia with lead acetate for 30 days and then it was injected with the alcoholic extract of capers leaves for 30 days, the sixth group was injected with britonia with acetate Lead for 30 days and then dosed with aqueous extract of capers leaves, the seventh group dosed with alcoholic extract of capers leaves and after 3 hours injected Britonia with lead acetate.

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