Comparison of the effect of aqueous extract of Artemisia herba alba and procaine penicillin on healing induced defect of the ear cartilage
Keywords:
aqueous extract, Artemisia herba alba, procaine penicillin, healing, ear cartilageAbstract
This study was undertaken to investigate the effect of aqueous extract of Artemisia herba alba (Asteraceae) and procaine penicillin on healing induced defect of the ear cartilage. A total of (25) female rats which used in this study were distributed randomly into five treatment group(five animals per each). Under routine surgery, all rats had circular holes in the elastic cartilage of their ears. All treatment groups were treated with local application daily for one week. Control group(C) treated with normal saline only. First treatment group(T1) treated with 5% Artemisia aqueous extract, second treatment group(T2) treated with 10% Artemisia aqueous extract, third treatment group(T3) treated with 15% Artemisia aqueous extract, fourth treatment group(T4) treated with procaine penicillin. The results showed that there was no significant differences between all treatment group except between (T3) and other treatment groups (1.857± 0.293). It could be concluded that concentration of aqueous extract at 15% (T3)affected significantly on reduce the diameter of ear defect after three weeks of treatment, the result of histo pathological test reveal that complete healing, absence of scar tissue, both edges of cartilage and fused together with marked fibrosis and formed large blood vessels.
Downloads
References
Mohamed A. E. H., El-Sayed, M. A., Hegazy, M. E., Helaly, S. E., Esmail, A. M., Mohamed, N. S. 2010 Antibacterial activity of Eudesmanolide compounds isolated from medicinal plant Artemisia herba-alba, Rec.Nat. Prod.,4:1-25.
Mohsen, H., & Ali, F. 2009. Essential oil composition of Artemisia herba-alba from southernTunisia. Molecules., 14:1585-1594.
Bezza, L., Mannarino, A., Fattarsi, K., Mikail, C., Abou, L., Hadji-Minaglou, F., & Kaloustian, J. 2010. Composition chimique de l’huile essentielle d’Artemisia herba-alba provenant de la région de Biskra (Algérie). Phytothérapie., 8: 277-281.
Goudjil, M. B., Ladjel, S., Bencheikh, S. E., Zighmi, S., & Hamada, D. 2015. Study of the chemical composition, antibacterial and antioxidant activities of the essential oil extracted from the leaves of Algerian Laurus nobilis Lauraceae. J Chem Pharm Res., 7: 379-385.
Hamedi, A., Zarshenas, M. M., Sohrabpour, M., & Zargaran, A. 2013. Herbal medicinal oils in traditional Persian medicine. Pharmaceutical Biology., 51: 1208-1218.
Arzu Akcal, Semra Karsidag, Kemalettin Yildiz, Nebil Yesiloglu , Mehmet Akif Akcal , Fevziye Kabukcuoglu. 2016 The effects of locally applied procaine on wound healing. Escrito por Arzu Akcal., 28 Noviembre.
SPSS 2011. User Guide: statistics, version 17. SPSS.lnc,chicago119.
Choi KM, Hwang DH, Shin KM, Yoon D-Y,Kim DS.2004.Effect of a Flavon extracted from Artemisia absinthium on collagen induced Arthritis in mice.Korean J. Pediatr.,47:677-84.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








