Prevalence of salivary gland neoplasms in the head and neck in educational hospitals in Cairo Governorate
Keywords:
Salivary gland neoplasms, epidemiology, world health organization, oral pathologyAbstract
Background: Salivary gland neoplasms are morphologically diverse neoplasms with variable histology, clinical behavior, and tumor grade. Moreover, specific gene translocations and fusions are associated with some types of SGNs. Aim: To evaluate the prevalence of salivary gland neoplasms diagnosed in Cairo's educational hospitals and to compare the results with findings in the literature. Materials and Methods: Data of salivary gland neoplasms diagnosed between 2010 and 2019 were collected from the files of the Cairo's educational hospitals. Results: Salivary gland neoplasms in the present study constituted 2.4% of all the 9609 registered oral and maxillofacial biopsies. A total of 231 cases of SGNs were collected and reviewed. Of these, (61.1%) were benign and (38.9%) were malignant. Minor salivary glands (51.94%) were more involved than major ones (45.02%). Pleomorphic adenoma was the most frequent type of benign SGNs (68.8%) while Mucoepidermoid carcinoma was the most frequent type of malignant SGNs (46.7%). The mean age of SGNs was 41.14 ±15.43 years with a slight male predilection. Conclusion: In this study we observed a marked geographic variation in the relative frequency of various salivary gland neoplasms in Cairo government.
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Al Sarraj, Y., Nair, S.C., Al Siraj, A. and AlShayeb, M., (2015). Characteristics of salivary gland tumours in the United Arab Emirates. Ecancermedicalscience, 9(583),1-7.
Al Sheddi, M.A., (2016). Salivary glands tumors: a single institution experience in Saudi Arabia. Biosciences Biotechnology Research Asia, 9(1), 193-198.
Alnour, A., (2017). Salivary Glands Tumors: A Clinicopathological Study about the Incidence and Distribution of Salivary Glands Tumors among a Syrian Population. Journal of Health Science, 5, 263-266.
Alsharif, M.N. and Alhomsi, K., (2020). Salivary glands tumors: demographics and occurrence according to age and gender. European Journal of Biomedical, 7(6), 508-514.
Araya, J., Martinez, R., Niklander, S., Marshall, M. and Esguep, A., (2015). Incidence and prevalence of salivary gland tumours in Valparaiso, Chile. Medicina Oral, Patologia Oral, Cirugia Bucal, 20(5), 532-539.
Bahra, J., Butt, F., Dimba, E. and Macigo, F., (2012). Patterns of salivary tumours at a university teaching hospital in Kenya. Open Journal of Stomatology, 2(4), 280-285.
Bittar, R.F., Ferraro, H.P., Gonçalves, F.T.M., da Cunha, M.G.C. and Biamino, E.R., (2015). Neoplasms of the salivary glands: analysis of 727 histopathological reports in a single institution. Polish Journal of Otolaryngology, 69(4), 28-33.
Bradley, P.J. and McGurk, M., (2013). Incidence of salivary gland neoplasms in a defined UK population. British Journal of Oral and Maxillofacial Surgery, 51(5), 399-403.
Cunha, J.L.S., Coimbra, A.C.P., Silva, J.V.R., do Nascimento, I.S., de Andrade, M.E., de Oliveira, C.R., et al., (2020). Epidemiologic analysis of salivary gland tumors over a 10-years period diagnosed in a northeast Brazilian population. Medicina Oral, Patologia Oral Y Cirugia Bucal, 25(4), 516-522.
Cunha, J.L.S., Hernandez-Guerrero, J.C., de Almeida, O.P., Soares, C.D. and Mosqueda-Taylor, A., (2021). Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review. Head and Neck Pathology, 15(2), 523-531.
da Silva, L.P., Serpa, M.S., Viveiros, S.K., Sena, D.A.C., de Carvalho Pinho, R.F., de Abreu Guimarães, L.D., et al., (2018). Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases. Journal of Cranio-Maxillofacial Surgery, 46(12), 2227-2233.
Fomete, B., Adebayo, E.T. and Ononiwu, C.N., (2015). Management of salivary gland tumors in a Nigerian tertiary institution. Annals of African Medicine, 14(3), 148-154.
Jaafari-Ashkavandi, Z., Ashraf, M.J. and Moshaverinia, M., (2013). Salivary gland tumors: a clinicopathologic study of 366 cases in southern Iran. Asian Pacific Journal of Cancer Prevention, 14(1), 27-30.
Kane, A.C., Ryan, W.R. and Cognetti, D., (2020). Salivary Gland Neoplasms. Current Otorhinolaryngology Reports, 8, 298–303.
Kızıl, Y., Aydil, U., Ekinci, Ö., Dilci, A., Köybaşıoğlu, A., Düzlü, M. et al., (2013). Salivary gland tumors in Turkey: demographic features and histopathological distribution of 510 patients. Indian Journal of Otolaryngology and Head and Neck Surgery, 65(1), 112-120.
Laishram, R.S., Kumar, A., Pukhrambam, G.D., Laishram, S. and Debnath, K., (2013). Pattern of salivary gland tumors in Manipur, India: A 10 year study. South Asian Journal of Cancer, 2(4), 250-253.
Lawal, A.O., Adisa, A.O., Kolude, B., Adeyemi, B.F. and Olajide, M.A., (2013). A review of 413 salivary gland tumours in the head and neck region. Journal of Clinical and Experimental Dentistry, 5(5), 218-222.
Lin, H.H., Limesand, K.H. and Ann, D.K., (2018). Current state of knowledge on salivary gland cancers. Critical Reviews™ in Oncogenesis, 23(3-4), 139–151.
Mengi, E., Kara, C.O., Tumkaya, F., Ardic, F.N., Topuz, B. and Bir, F., 2020. Salivary gland tumors: A 15-year experience of a university hospital in Turkey. Northern Clinics of İstanbul, 7(4), 366-371.
Noel, L., Medford, S., Islam, S., Muddeen, A., Greaves, W. and Juman, S., (2018). Epidemiology of salivary gland tumours in an Eastern Caribbean nation: A retrospective study. Annals of Medicine and Surgery, 36, 148-151.
Parkins, G.E., Blankson, P.K., Affum, A., Boamah, M.O. and Sackeyfio, J., (2021). Salivary gland neoplasms: A 10-year review of a major referral center in Ghana. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 131(2), 161-165.
Peravali, R.K., Bhat, H.H.K., Upadya, V.H., Agarwal, A. and Naag, S., (2015). Salivary gland tumors: a diagnostic dilemma!. Journal of Maxillofacial and Oral Surgery, 14(1), 438-442.
Pfeiffer, J. and Ridder, G.J., (2012). Diagnostic value of ultrasound-guided core needle biopsy in patients with salivary gland masses. International Journal of Oral and Maxillofacial Surgery, 41(4), 437-443.
Quiriny, M., Dekeyser, C., Moreau, M., Digonnet, A., Willemse, E., Vanbel, L. et al., (2017). Benign tumors of the parotid gland: a retrospective study of 339 patients. Acta Chirurgica Belgica, 117(4), 227-231.
Reinheimer, A., Daniella-Serafin-Couto Vieira, M.M. and Cordeiro, R., (2019). Retrospective study of 124 cases of salivary gland tumors and literature review. Journal of Clinical and Experimental Dentistry, 11(11), 1025-1032.
Saghravanian, N., Ghazi, N. and Saba, M., (2013). Clinicopathologic evaluation of salivary gland neoplasms: a 38-year retrospective study in Iran. Annals of Diagnostic Pathology, 17(6), 522-525.
Sando, Z., Fokouo, J.V., Mebada, A.O., Djomou, F., NDjolo, A. and Oyono, J.L.E., (2016). Epidemiological and histopathological patterns of salivary gland tumors in Cameroon. Pan African Medical Journal, 23(1), 1-8.
Schvartsman, G., Pinto, N.A., Bell, D. and Ferrarotto, R., (2019). Salivary gland tumors: Molecular characterization and therapeutic advances for metastatic disease. Head and Neck, 41(1), 239-247.
Seethala, R.R. and Stenman, G., (2017). Update from the 4th edition of the World Health Organization classification of head and neck tumours: tumors of the salivary gland. Head and Neck Pathology, 11(1), 55-67.
Shen, S.Y., Wang, W.H., Liang, R., Pan, G.Q. and Qian, Y.M., (2018). Clinicopathologic analysis of 2736 salivary gland cases over a 11-year period in Southwest China. Acta Oto-Laryngologica, 138(8), 746-749.
Shishegar, M., Ashraf, M.J., Azarpira, N., Khademi, B., Hashemi, B. and Ashrafi, A., (2011). Salivary gland tumors in maxillofacial region: a retrospective study of 130 cases in a southern Iranian population. Pathology Research International, 2011.
Taghavi, N., Sargolzaei, S., Mashhadiabbas, F., Akbarzadeh, A. and Kardouni, P., (2016). Salivary gland tumors: a 15-year report from Iran. Turkish Journal of Pathology, 32(1), 35-9.
Vasconcelos, A.C., Nör, F., Meurer, L., Salvadori, G., Souza, L.B.D., Vargas, P.A., et al., (2015). Clinicopathological analysis of salivary gland tumors over a 15-year period. Brazilian Oral Research, 30, 1-7.
Wang, X.D., Meng, L.J., Hou, T.T. and Huang, S.H., (2015). Tumours of the salivary glands in northeastern China: a retrospective study of 2508 patients. British Journal of Oral and Maxillofacial Surgery, 53(2), 132-137.
Živković, N., Kostić, M., Cvetanović, A., Milentijević, M.J., Spasić, M., Petrović, M., et al., (2021). Differential challenges in salivary gland neoplasms. Archives of Biological Sciences, 73(1), 65-72.
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