Assessment of inhaler techniques and the impact of critical errors on clinical outcomes

https://doi.org/10.53730/ijhs.v6nS7.13074

Authors

  • Xuan Wen Ee Pharmacy Department, Sultanah Aminah Hospital, Persiaran Abu Bakar, 80000 Johor Bahru, Johor, Malaysia
  • Nurdiana Jamil Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
  • Wan Sazrina Wan Zaid Superbig Academy & Superbig Capital Limited, Unit F1-2, Block F, Jalan Radius 1/1c, Street Teknokrat 2/1, Radius, 63000 Cyberjaya, Selangor Malaysia

Keywords:

inhaler techniques, pharmacist, disease control

Abstract

Introduction: The use of inhaled medications remained as the pillar in pharmacological management of asthma and chronic obstructive pulmonary disease. Incorrect inhalation technique can impact drug delivery to the lung, compromised bronchodilation and lead to deteriorated disease control and worse disease outcomes. However, devices for inhaled medications can be difficult to learn and prone to mishandling despite presence of newer and more user-friendly inhalers. Objectives: This study aimed to assess and compare between patients’ self-rated confidence with their actual technique in using inhalers This study also aimed to determine factors associated with incorrect inhalation technique and impact of inhaler critical errors on clinical outcomes. Methodology: This was a cross-sectional study among patients with chronic respiratory disease who were users of inhalers, who visited outpatient pharmacy department and respiratory clinic, Serdang Hospital from 15th July to 15th August 2019. The patients were screened using convenient sampling according to inclusion and exclusion criteria. Pertinent data and inhalation techniques were identified during interview sessions. Results and discussion: Nearly a third of the patients who were confident with their inhalation technique had incorrect inhalation techniques and performed critical errors. 

Downloads

Download data is not yet available.

References

Afonso, A. S. M., Verhamme, K. M. C., Sturkenboom, M. C. J. M., & Brusselle, G. G. O. (2011). COPD in the general population: Prevalence, incidence and survival. Respiratory Medicine, 105(12), 1872–1884. https://doi.org/https://doi.org/10.1016/j.rmed.2011.06.012

Arora, P., Kumar, L., Vohra, V., Sarin, R., Jaiswal, A., Puri, M. M., … Chakraborty, P. (2014). Evaluating the technique of using inhalation device in COPD and Bronchial Asthma patients. Respiratory Medicine, 108(7), 992–998. https://doi.org/https://doi.org/10.1016/j.rmed.2014.04.021

Aydemir, Y. (2015). Assessment of the factors affecting the failure to use inhaler devices before and after training. Respiratory Medicine, 109(4), 451–458. https://doi.org/https://doi.org/10.1016/j.rmed.2015.02.011

Bosnic-Anticevich, S. Z., Cvetkovski, B., Azzi, E. A., Srour, P., Tan, R., & Kritikos, V. (2018). Identifying Critical Errors: Addressing Inhaler Technique in the Context of Asthma Management. Pulmonary Therapy, 4(1), 1–12. https://doi.org/10.1007/s41030-018-0051-0

Capstick, T. G. D. (2013). Inhaler Technique and Training in People With Chronic Obstructive Pulmonary Disease and Asthma: Effects of Particle Size on Lung Deposition. Medscape, 91–103.

Chorão, P., Pereira, A. M., & Fonseca, J. A. (2014). Inhaler devices in asthma and COPD - An assessment of inhaler technique and patient preferences. Respiratory Medicine, 108(7), 968–975. https://doi.org/10.1016/j.rmed.2014.04.019

Chrystyn, H., & Price, D. (2009). Not all asthma inhalers are the same: Factors to consider when prescribing an inhaler. Primary Care Respiratory Journal, 18(4), 243–249. https://doi.org/10.4104/pcrj.2009.00029

D., P., D.L., K., B., V., M., G., S., W., & F.S., G. (2018). Factors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey. International Journal of COPD, 13, 695–702. https://doi.org/10.2147/COPD.S149404

Darba, J., Ramírez, G., García-Bujalance, L., Torvinen, S., Sánchez-de la Rosa, R., & Sicras, A. (2016). Identification of factors involved in medication compliance: incorrect inhaler technique of asthma treatment leads to poor compliance. Patient Preference and Adherence, 135. https://doi.org/10.2147/ppa.s95303

de Marco, R., Pesce, G., Marcon, A., Accordini, S., Antonicelli, L., Bugiani, M., … Verlato, G. (2013). The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD): Prevalence and Risk Factors in Young, Middle-aged and Elderly People from the General Population. PLoS ONE, 8(5), 1–7. https://doi.org/10.1371/journal.pone.0062985

Ding, B., Small, M., Scheffel, G., & Holmgren, U. (2018). Maintenance inhaler preference, attribute importance, and satisfaction in prescribing physicians and patients with asthma, COPD, or asthma–COPD overlap syndrome consulting for routine care. International Journal of COPD, 13, 927–936. https://doi.org/10.2147/COPD.S154525

Duangrithi, D., Saiprom, K., SaeTew, J., & Sa-u, Y. (2017). Impact of exacerbation on the errors of inhaler techniques in COPD patients. Journal of Applied Pharmaceutical Science, 7(5), 84–89. https://doi.org/10.7324/JAPS.2017.70515

Gutiérrez-Pereyra, F., Plaza, V., Fernández-Rodríguez, C., Melero, C., Cosío, B. G., Entrenas, L. M., … López-Viña, A. (2015). Validation of the “test of the adherence to inhalers” (TAI) for asthma and COPD patients. 1.11 Clinical Problems - Asthma, 28(00), PA5012. https://doi.org/10.1183/13993003.congress-2015.PA5012

Harnett, C. M., Hunt, E. B., Bowen, B. R., O’Connell, O. J., Edgeworth, D. M., Mitchell, P., … Murphy, D. M. (2014). A study to assess inhaler technique and its potential impact on asthma control in patients attending an asthma clinic. Journal of Asthma, 51(4), 440–445. https://doi.org/10.3109/02770903.2013.876650

Hashmi, A., Soomro, J. A., Memon, A., & Soomro, T. K. (2012). Incorrect inhaler technique compromising quality of life of asthmatic patients. Journal of Medicine, 13(1), 16–21. https://doi.org/10.3329/jom.v13i1.7980

Ilic, A. D., Zugic, V., Zvezdin, B., Kopitovic, I., Cekerevac, I., Cupurdija, V., … Barac, A. (2016). Influence of inhaler technique on asthma and COPD control: A multicenter experience. International Journal of COPD, 11(1), 2509–2517. https://doi.org/10.2147/COPD.S114576

Janežič, A., Locatelli, I., & Kos, M. (2019). Inhalation technique and asthma outcomes with different corticosteroid-containing inhaler devices. Journal of Asthma, 0(0), 1–9. https://doi.org/10.1080/02770903.2019.1591442

Jones, P. W., Harding, G., Berry, P., Wiklund, I., Chen, W. H., & Kline Leidy, N. (2009). Development and first validation of the COPD Assessment Test. European Respiratory Journal, 34(3), 648–654. https://doi.org/10.1183/09031936.00102509

Kocks, J. W. H., Chrystyn, H., van der Palen, J., Thomas, M., Yates, L., Landis, S. H., … Molimard, M. (2018). Systematic review of association between critical errors in inhalation and health outcomes in asthma and COPD. Npj Primary Care Respiratory Medicine, 28(1), 1–6. https://doi.org/10.1038/s41533-018-0110-x

Lavorini, F., Corrigan, C. J., Barnes, P. J., Dekhuijzen, P. R. N., Levy, M. L., Pedersen, S., … Crompton, G. K. (2011). Retail sales of inhalation devices in European countries: So much for a global policy. Respiratory Medicine, 105(7), 1099–1103. https://doi.org/10.1016/j.rmed.2011.03.012

Lee, H., Boo, S., Lim, Y., Kim, S., & Kim, I. A. (2014). Accuracy of Inhaler Use in Patients With Chronic Obstructive Pulmonary Disease. Clinical Nursing Research, 23(5), 560–574. https://doi.org/10.1177/1054773813498269

Melzer, A. C., Ghassemieh, B. J., Gillespie, S. E., Lindenauer, P. K., McBurnie, M. A., Mularski, R. A., … Au, D. H. (2017). Patient characteristics associated with poor inhaler technique among a cohort of patients with COPD. Respiratory Medicine, 123, 124–130. https://doi.org/https://doi.org/10.1016/j.rmed.2016.12.011

Musafiri, S., Van Meerbeeck, J., Musango, L., Brusselle, G., Joos, G., Seminega, B., & Rutayisire, C. (2011). Prevalence of atopy, asthma and COPD in an urban and a rural area of an African country. Respiratory Medicine, 105(11), 1596–1605. https://doi.org/10.1016/j.rmed.2011.06.013

Nathan, R. A., Sorkness, C. A., Kosinski, M., Schatz, M., Li, J. T., Marcus, P., … Pendergraft, T. B. (2004). Development of the Asthma Control Test: A survey for assessing asthma control. Journal of Allergy and Clinical Immunology, 113(1), 59–65. https://doi.org/10.1016/j.jaci.2003.09.008

Parreira, J. G., Eduardo, T., Pfiffer, F., Soldá, S., Malheiros, C., & Rasslan, S. (2014). Factors related to the incorrect use of inhalers by asthma patients. Rev Assoc Med Bras, 48(4), 297–302.

Plaza, V., López-Viña, A., Entrenas, L. M., Fernández-Rodríguez, C., Melero, C., Pérez-Llano, L., … Cosio, B. G. (2016). Differences in Adherence and Non-Adherence Behaviour Patterns to Inhaler Devices Between COPD and Asthma Patients. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(5), 547–554. https://doi.org/10.3109/15412555.2015.1118449

Press, V. G., Arora, V. M., Shah, L. M., Lewis, S. L., Ivy, K., Charbeneau, J., … Krishnan, J. A. (2011). Misuse of respiratory inhalers in hospitalized patients with asthma orCOPD. Journal of General Internal Medicine, 26(6), 635–642. https://doi.org/10.1007/s11606-010-1624-2

Price, D., Bosnic-Anticevich, S., Briggs, A., Chrystyn, H., Rand, C., Scheuch, G., & Bousquet, J. (2013). Inhaler competence in asthma: Common errors, barriers to use and recommended solutions. Respiratory Medicine, 107(1), 37–46. https://doi.org/10.1016/j.rmed.2012.09.017

Price, David, David-Wang, A., Cho, S. H., Ho, J. C. M., Jeong, J. W., Liam, C. K., … Neira, G. (2016). Asthma in Asia: Physician perspectives on control, inhaler use and patient communications. Journal of Asthma, 53(7), 761–769. https://doi.org/10.3109/02770903.2016.1141951

Rootmensen, G. N., van Keimpema, A. R. J., Jansen, H. M., & de Haan, R. J. (2010). Predictors of Incorrect Inhalation Technique in Patients with Asthma or COPD: A Study Using a Validated Videotaped Scoring Method. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 23(5), 323–328. https://doi.org/10.1016/0009-8981(86)90060-4

Soriano, J. B., Abajobir, A. A., Abate, K. H., Abera, S. F., Agrawal, A., Ahmed, M. B., … Vos, T. (2017). Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet Respiratory Medicine, 5(9), 691–706. https://doi.org/10.1016/S2213-2600(17)30293-X

Usmani, O. S., Lavorini, F., Marshall, J., Dunlop, W. C. N., Heron, L., Farrington, E., & Dekhuijzen, R. (2018). Critical inhaler errors in asthma and COPD: A systematic review of impact on health outcomes. Respiratory Research, 19(1), 9–12. https://doi.org/10.1186/s12931-017-0710-y

Yildiz, F. (2014). Importance of Inhaler Device Use Status in the Control of Asthma in Adults: The Asthma Inhaler Treatment Study. Respiratory Care, 59(2), 223–230. https://doi.org/10.4187/respcare.02478

Published

29-09-2022

How to Cite

Ee, X. W., Jamil, N., & Zaid, W. S. W. (2022). Assessment of inhaler techniques and the impact of critical errors on clinical outcomes. International Journal of Health Sciences, 6(S7), 4877–4895. https://doi.org/10.53730/ijhs.v6nS7.13074

Issue

Section

Peer Review Articles

Most read articles by the same author(s)