An insight of development and validation of bio-analytical method in the reference of anti-diabetic drugs by using LC-MS/MS

Ranjit Prasad Swain; Nihar Ranjan Kar; Bodala Chandrika Kumari; Biswanath Prusty; Jochhana Rani Bhuyan; Itishree Nayak; Chandan Nayak

doi:10.53730/ijhs.v6nS8.13153

An insight of development and validation of bio-analytical method in the reference of anti-diabetic drugs by using LC-MS/MS

https://doi.org/10.53730/ijhs.v6nS8.13153

Authors

Ranjit Prasad Swain 1Assistant Professor, Dept. of Pharmaceutics, School of Pharmaceutical Sciences Siksha ‘O’ Anusandhan (Deemed to be University), Bhubneswar, Odisha
Nihar Ranjan Kar Assistant Professor, School of Pharmacy, Centurion University of Technology and Management, Odisha
Bodala Chandrika Kumari 3Assistant professor, Gayatri institute of Science and Technology, Gunupur, Rayagada , Odisha
Biswanath Prusty Assistant Professor, College of pharmaceutical sciences, Mohuda, Berhampur, Odisha
Jochhana Rani Bhuyan Assistant Professor, College of pharmaceutical sciences, Mohuda, Berhampur, Odisha
Itishree Nayak Assistant Professor, College of pharmaceutical sciences, Mohuda, Berhampur, Odisha
Chandan Nayak
nayakchandan279@gmail.com
Assistant Professor, School of Pharmaceutical Education & Research, Berhampur University, Bhanja Bihar, Berhampur, Ganjam, Odisha

Abstract

Diabetes mellitus, which has high rates of disability and mortality, is one of the main causes of public health concerns worldwide. It currently poses serious medical and societal issues. Different bio-analytical techniques have been developed to identify the pharmaceutical formulation of the anti-diabetic drug. Due to the continual requirement to achieve improved sensitivity, accuracy, and speed of analysis in complex biological samples, the development of bio-analytical sample preparation techniques has grown more difficult over time (e.g., blood, serum, plasma, saliva, feces, and urine). This is a mini review, and its goal is to analyze how LC-MS/MS has been used to for the pharmaceutical formulation of the anti-diabetic drugs. The method was validated for linearity, accuracy, precision, specificity, selectivity, and stability.

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Published

30-09-2022

How to Cite

Swain, R. P., Kar, N. R., Kumari, B. C., Prusty, B., Bhuyan, J. R., Nayak, I., & Nayak, C. (2022). An insight of development and validation of bio-analytical method in the reference of anti-diabetic drugs by using LC-MS/MS. International Journal of Health Sciences, 6(S8), 4278–4287. https://doi.org/10.53730/ijhs.v6nS8.13153

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Issue

Vol. 6 No. S8 (2022)

Section

Peer Review Articles

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