Macular optical coherence tomography (OCT) changes in anisometropic amblyopia before and after part time occlusion treatment

https://doi.org/10.53730/ijhs.v6nS6.13171

Authors

  • Mohamed Yasser Sayed Saif Professor of Ophthalmology, Beni-Suef University
  • Ahmed Reda Awadein Professor of Ophthalmology – Cairo University
  • Asmaa Mohammed Samir Lecturer of Ophthalmology – Beni-Suef University
  • Ossama Ahmed El-Naggar Consultant of Ophthalmology (MD), General Organization of Teaching Hospitals and Institutes
  • Alaa El-Din Ibrahim Mohammed El-Sawy M.B.B. Ch, M.Sc - Al-Azher University

Keywords:

macular optical coherence tomography (OCT), anisometropic, amblyopia, BCVA

Abstract

Background: Amblyopia denotes unilateral (or rarely bilateral) decrease of best corrected visual acuity (BCVA) with no identifiable organic pathology of the eye or visual pathway.  It results from vision deprivation and/or abnormal binocular interaction. Aim and objectives: The aim of work was to measure the thickness of macula, nerve fiber layer, and ganglion cell layer by the use of optical coherence tomography (OCT) in eyes with anisometropic amblyopia before and after part-time occlusion therapy. Patients and methods: It was a prospective comparative clinical study conducted during the period from June 2020 through December 2020 and Mattaria teaching hospital. The total sample size is 50 eyes of 50 participants.  Each treatment should have a confidence level of 95% and a margin error of 5%. Results: There was a statistically significant difference in the central macular thickness when compared before and after amblyopia treatment (the difference was more than 10 µm in 11 patients, while it was less than 10 µm in the rest of the patients), while the difference was statistically insignificant in either average macular thickness or total volume.

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References

Alotaibi, A. G., & Al Enazi, B. (2011). Unilateral amblyopia: Optical coherence tomography findings. Saudi Journal of Ophthalmology, 25(4), 405-409.

Andalib, D., Javadzadeh, A., Nabai, R., & Amizadeh, Y. (2013). Macular and retinal nerve fiber layer thickness in unilateral anisometropic or strabismic amblyopia. Journal of Pediatric Ophthalmology & Strabismus, 50(4), 218-221.‏

Dickmann, A., Petroni, S., Salerni, A., Dell'Omo, R., & Balestrazzi, E. (2009). Unilateral amblyopia: an optical coherence tomography study. Journal of American Association for Pediatric Ophthalmology and Strabismus, 13(2), 148-150.‏

Donahue, S. P. (2005). The relationship between anisometropia, patient age, and the development of amblyopia. Transactions of the American Ophthalmological Society, 103, 313.

Huynh, S. C., Samarawickrama, C., Wang, X. Y., Rochtchina, E., Wong, T. Y., Gole, G. A., et al. (2009). Macular and nerve fiber layer thickness in amblyopia: the Sydney Childhood Eye Study. Ophthalmology, 116(9), 1604-1609.‏

Liu, C. H., Ong, S. J., Huang, C. Y., Wu, W. C., Kao, L. Y., & Yang, M. L. (2018). Macular thickness, foveal volume, and choroidal thickness in amblyopic eyes and their relationships to the treatment outcome. Journal of Ophthalmology, 2018.‏

Machoy, M., Seeliger, J., Szyszka-Sommerfeld, L., Koprowski, R., Gedrange, T., & Woźniak, K. (2017). The use of optical coherence tomography in dental diagnostics: a state-of-the-art review. Journal of healthcare engineering, 2017.‏

Salmon, J. (2019). Kanski's Clinical Ophthalmology E-Book: A Systematic Approach. Elsevier Health Sciences.‏

Szigeti, A., Tátrai, E., Szamosi, A., Vargha, P., Nagy, Z. Z., Németh, J., et al. (2014). A morphological study of retinal changes in unilateral amblyopia using optical coherence tomography image segmentation. PloS one, 9(2), e88363.‏

Tugcu, B., Araz-Ersan, B., Erdogan, E. T., Tarakcioglu, H., Coskun, C., Yigit, U., et al. (2014). Structural and functional comparison of the persistent and resolved amblyopia. Documenta Ophthalmologica, 128(2), 101-109.‏

Published

01-10-2022

How to Cite

Saif, M. Y. S., Awadein, A. R., Samir, A. M., El-Naggar, O. A., & El-Sawy, A. E.-D. I. M. (2022). Macular optical coherence tomography (OCT) changes in anisometropic amblyopia before and after part time occlusion treatment. International Journal of Health Sciences, 6(S6), 11405–11417. https://doi.org/10.53730/ijhs.v6nS6.13171

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Section

Peer Review Articles