Analysis of clinical profile of malaria patients attending a tertiary care centre in Central India

https://doi.org/10.53730/ijhs.v6nS9.13191

Authors

  • Harendra Singh Jadon Senior Resident, Department of Medicine, Govt. Medical College Datia, M.P.
  • Jitendra Mourya Senior Resident, Department of Medicine, Govt. Medical College Datia, M.P.
  • Sachin Singh Yadav Associate Professor, Department of Community Medicine, Govt. Medical College Datia, M.P.

Keywords:

Malaria, P. Vivax, P. falciparum, clinical profile

Abstract

Background: Malaria is the commonest parasitic infection in India. A shift in the clinical profile in patients with complicated malaria has been observed with multiple organ dysfunctions becoming a common feature. Aim: This study is aimed to evaluate the clinical profile of malaria in a tertiary care hospital, central India. Material and Methods: A prospective study was carried out at a tertiary care hospital of a medical college in M.P. India. Patients of 18 years age or above who were smear positive or antigen positive were included in the study. Results:  A total of 230 malaria cases were present, of which 54.8% were males. The mean age of the participants was 34.7 years. Prevalence was common in rural (64.8%) and lower socio-economic class (46.1%) population. Fever weakness/nausea and headache were the most common presenting complaints (94.3% and 85.7% and 71.3% respectively) and pallor, jaundice and hepato splenomegaly were the foremost sign. Plasmodium Vivax (53%) was the most common infection. Conclusion: Malaria has a male preponderance. Fever, headache, weakness, pallor and splenomegaly were the common clinical presentation.

Downloads

Download data is not yet available.

References

Santosh kumar RJ, Manjunath S, Sharanabasappa MA. Prescription pattern of antimalarial drugs in a tertiary care hospital. Asian Pac J Trop Dis. 2010;3(5):379-81

World Health Organisation, Regional office of South East Region Health topics: Malaria: World Malaria report; 2014. Available from: http://www.searo.who.int/entity /malaria /en

Operational Manual for malaria elimination in India 2016, NVBDCP, DGHS, Ministry of Health and Family Welfare. 2016; Available from: https:// nvbdcp.gov.in/Write Read Data/l892s/5232542721532941542.

Wongsrichanalai C, Wernsdorfer WH, Muth S, Sutamihardja A, Barcus MJ. A Review of Malaria Diagnostic Tools: Microscopy and rapid diagnostic test (RDT), Am J trop Med Hyg. 2007:77(6), 119-27.

Kochar DK, Sirohi P, Kochar SK. Malaria in India. Ed Singal SK. Medicine updates (proceedings of scientific session -APICON 2007; 17:639-48.

Singh P, Mehta N, Tada NG. Comparison of clinical profile and severity of P. falciparum and P. vivax malaria in a tertiary care hospital of Surat, India. Int J Contemp Pediatr 2016; 3:1288-92.

Talib VH, Hasija BD, Verma MC. Some observations on changing trends of malaria. JAPI 1992;49:381-3

Estimation of true malaria burden. World Health Report, Geneva. World health Organisation 2008

National drug policy on malaria 2010, Directorate of National Vector Borne Disease Control Programme, Directorate General of Health Services, Ministry of Health and Family Welfare

D. K. Kochar, V. Saxena, N. Singh, S. K. Kochar, S. V. Kumar, and A. Das, “Plasmodium vivax malaria,” Emerging Infectious Diseases, vol. 11, no. 1, pp. 132–134, 2005.

D. K. Kochar, A. Das, S. K. Kochar et al., “Severe Plasmodium vivax malaria: a report on serial cases from Bikaner in northwestern India,” American Journal of Tropical Medicine and Hygiene, vol. 80, no. 2, pp. 194–198, 2009

Kaushik JS, Gomber S, Dewan P. Clinical and epidemiological profiles of severe malaria in children from Delhi, India. J Health Popul Nutr2012; 30: 113‑6

Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Trans R Soc Trop Med Hyg. 2000; 94:S1-90.

Erhart LM, Yingyuen K, Chuanak N, et al. Hematologic and clinical indices of malaria in a semi-immune population of western Thailand. Am J Trop Med Hyg. 2004; 70(1):8–14.

Jadhav UM, Patkar VS, Kadam NN. Thrombocytopenia in malaria-correlation with type and severity of malaria. J Assoc Physicians India. 2004; 52:615–618.

Laura Chery, Jennifer N. Maki, Anjali Mascarenhas, Jayashri T. Walke, Pooja Gawas, Anvily Almeida et al Demographic and clinical profiles of Plasmodium falciparum and Plasmodium Vivax patients at a tertiary care centre in southwestern India, Malar J (2016) 15:569 DOI 10.1186/s12936-016-1619-5

Bashawri LAM, Mandil AA, Bahnassy AA, Ahmed MA. Malaria: haemato¬logical aspects. Ann Saudi Med. 2002; 22:372–377.

Dr. Ronak Bhalodia, Dr. Nirmal Chaudhari and Dr. Jyotin Shah. 2019. “Study of clinical profile of P. falciparum malaria in tertiary care hospital”, International Journal of Current Research 11, (12), 8748-8751

Jagdish Prasad Goyal and Aarti M. Makwana Comparison of Clinical Profile between P. vivax and P. falciparum Malaria in Children: A Tertiary Care Centre Perspective from India, Malaria Research and Treatment Volume 2014, Article ID 132672, 4 pages http://dx.doi.org/10.1155/2014 /132672

Manju Kumari and Radha Ghildiyal, Clinical Profile of Plasmodium Vivax Malaria in Children and, Study of Severity Parameters in relation to Mortality: A Tertiary Care Centre Perspective in Mumbai, India, Malaria Research and Treatment Volume 2014, Article ID 765657, 6 pages http://dx.doi.org/10.1155/2014/765657

Murthy RN, Rai S. Analysis of clinical profile and prescription pattern of malaria in a tertiary care hospital in Karnataka. Int J Basic Clin Pharmacol 2019; 8:1744-8.

Antony J, Celine TM, Chacko M. Staging back of Malaria in Kerala, India: A Retrospective study. Int Res J Social Sci. 2013;2(12):42-6

Narender Pal Jain*, Shweta Gupta*, Sanjeev Kumar Singla*, Sanchit Budhiraja* Rajesh Mahajan. Prospective Study Of The Clinical Profile Of Hospitalized Patients Of Malaria, NJIRM 2013; Vol. 4(4).July - August eISSN: 0975-9840 pISSN: 2230 – 9969

Murthy GL, Sahay RK, Srinivasan VR, Upadhaya AC, Shantaram V and Gayatri K. Clinical profile, of falciparum Malaria in a tertiary care hospital. J Indian Med Assoc. 2000; 98(4): 160-2, 169.

Gupta et al. Clinical Profile and Prognostic Indicators in Adults Hospitalized with Severe Malaria Caused by Different Plasmodium Species. Infectious Diseases: Research and Treatment 2015:8 45–50 doi:10.4137/IDRT.S34039

Shelat VV, Pandve HT, Pathak G. Sociodemographic characters, clinical profile and laboratory parameters in malaria cases due Plasmodium falciparum and Plasmodium vivax comparative study. J Med Trop 2014;16:76-80

Pavithra H, Ismail IM, Kahar A, Bhargav S, Bharadhwaj SMG, Kumar MA, et al. Clinical profile and geographical distribution of malaria patients attending a tertiary care centre in Mangaluru, South India. Int J Community Med Public Health 2019; 6:4743-7.

Waris, R., Aurangzeb, B., Raza, S.H., Waris, A., Riaz, R. Clinical Profile and Spectrum of Complications of Malaria in Hospitalized Children at a Tertiary Care Hospital. Journal of Rawalpindi Medical College. 31 Dec. 2021; 25(4): 516-520. DOI: https:// doi.org/10.37939/jrmc.v25i4.1752

Minhas A, Mane P, Sangwan J, Dhingra A. Pattern of severe malaria with special reference to Plasmodium vivax in pediatric population of the most aspirational region of North India. Int J Adv Med Health Res 2021;8:57-62.

Kumar A, Ahmar R, Kishore S, Gupta AK, Kumar R, Kumar M, Sharan S, Prakash J. Clinical profile of malaria in children at a tertiary care hospital of Bihar and evaluation of parasite LDH based rapid diagnostic test for malaria. Panacea J Med Sci 2021; 11(1):106-110.

Rathod SN, Chavan A, Sharma S, Rathod T, Khan N, Bavdhankar K. Changing clinical profile of malaria at a tertiary care hospital. Int J Adv Med 2018; 5:510-3.

Madhuri P. Kadam* Study of Clinical Profile of Malaria and its management in Pediatric age group at urban hospital, International Journal of Health and Clinical Research, 2021;4(2):244-248 e-ISSN: 2590-3241, p-ISSN: 2590-325X

Virendra C. patil1, Harsha V. Patil, Clinical Profile and Outcome of Complicated Plasmodium falciparum Malaria, International Journal of Medicine and Public health [Int. J. Med. Public health] | Vol 2 | Issue 1 | 2012

Singh P, Mehta N, Tada NG. Comparison of clinical profile and severity of P. falciparum and P.Vivax malaria in a tertiary care hospital of Surat, India. Int J Contemp Pediatr 2016;3:1288-92

Hirani MM, Vadhvana SK. Study of Clinical Profile of P.Vivax Malaria during Pregnancy. J Res Med Den Sci 2015;3(4):307-11

Published

02-10-2022

How to Cite

Jadon, H. S., Mourya, J., & Yadav, S. S. (2022). Analysis of clinical profile of malaria patients attending a tertiary care centre in Central India. International Journal of Health Sciences, 6(S9), 3020–3026. https://doi.org/10.53730/ijhs.v6nS9.13191

Issue

Section

Peer Review Articles

Most read articles by the same author(s)