Fascin expression in breast cancer
Keywords:
Fascin, Breast, CancerAbstract
Background: The present study was conducted for assessing Fascin expression in breast cancer patients. Materials & methods: A total of 50 patients diagnosed histopathologically with breast cancer were enrolled. Complete demographic details of all the subjects were recorded. Clinical and radiographic examination of all the subjects was done. Blood samples were obtained from all the subjects and biochemical along with haematological profile was assessed. Lymph node status in all the patients was evaluated. Fascin expression was assessed in all the patients. Results: Fascin expression was positive in 36 percent of the patients. Mean age of the patients with positive and negative Fascin expression was 52.3 percent and 55.4 percent respectively. Lympho-vascular expression was present in 66.67 percent and 50 percent of the patients with Fascin positive and negative expression respectively. Lymph node involvement was present in 72.22 percent and 62.5 percent of the patients with Fascin positive and negative expression respectively. Conclusion: Fascin expression in breast cancer cells offers a potential therapeutic intervention in breast cancer treatment.
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