Neonatal characteristics and conditions contributed to stunting: A systematic review and meta-analysis

Riyani Wulandari; Dewi Kartika Sari; Siti Fatmawati; Rina Sri Widayati

doi:10.53730/ijhs.v6n3.13266

Authors

Riyani Wulandari
riyaniwulandari24@gmail.com
Universitas Aisyiyah, Surakarta, Indonesia
Dewi Kartika Sari Universitas Aisyiyah, Surakarta, Indonesia
Siti Fatmawati Universitas Aisyiyah, Surakarta, Indonesia
Rina Sri Widayati Universitas Aisyiyah, Surakarta, Indonesia

Keywords:

children, characteristics, conditions, neonatal, stunting

Abstract

Globally, stunting is one of the most serious and challenging public health problems in the world. It is critical to have information on how to reduce stunting. Therefore, this study aimed to identify neonatal determinants of stunting among children under five years. This meta-analysis searched for observational studies published in English from 2000 to 2022 focusing on the association between neonatal characteristics and conditions affecting the incidence of stunting in children aged 0-5 years. We searched in Google Scholar, PubMed, and other online databases. Two review authors independently selected studies for inclusion, extracted data, and assessed the risk of bias in the included studies. The pooled analysis was carried out using software review manager (RevMan) 5.3. Pooled analysis indicated that children under 5 years with anemia or whoever had diarrhea had a higher odds of becoming stunted than those who did not have anemia or not ever had diarrhea and both of these results were statistically significant. Male children had a higher odds of stunting compared to female children. Our study suggest that anemia, recently had diarrhea, and boys are risk factors of stunting.

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References

A Balalian, A., Simonyan, H., Hekimian, K., Deckelbaum, R. J., & Sargsyan, A. (2017). Prevalence and determinants of stunting in a conflict-ridden border region in Armenia - a cross-sectional study. BMC Nutrition, 3, 85.

Adhikari, R. P., Shrestha, M. L., Acharya, A., & Upadhaya, N. (2019). Determinants of stunting among children aged 0-59 months in Nepal: findings from Nepal Demographic and health Survey, 2006, 2011, and 2016. BMC Nutrition, 5, 37.

Altare, C., Delbiso, T. D., Mutwiri, G. M., Kopplow, R., & Guha-Sapir, D. (2016). Factors Associated with Stunting among Pre-school Children in Southern Highlands of Tanzania. Journal of Tropical Pediatrics, 62(5), 390–408.

Ayelign, A., & Zerfu, T. (2021). Household, dietary and healthcare factors predicting childhood stunting in Ethiopia. Heliyon, 7(4), e06733. https://doi.org/10.1016/j.heliyon.2021.e06733

Berhe, K., Seid, O., Gebremariam, Y., Berhe, A., & Etsay, N. (2019). Risk factors of stunting (chronic undernutrition) of children aged 6 to 24 months in Mekelle City, Tigray Region, North Ethiopia: An unmatched case-control study. PloS One, 14(6), e0217736

Bocheliuk, V. Y., Spytska, L. V., Mamicheva, O. V., Panov, M. S., & Kordonets, V. V. (2021). Psychological features of post-COVID syndrome course. International Journal of Health Sciences, 5(3), 276–285. https://doi.org/10.53730/ijhs.v5n3.1503

Chen, S. J., Vohr, B. R., & Oh, W. (1993). Effects of birth order, gender, and intrauterine growth retardation on the outcome of very low birth weight in twins. The Journal of Pediatrics, 123(1), 132–136. https://doi.org/10.1016/s0022-3476(05)81556-2

Chirande, L., Charwe, D., Mbwana, H., Victor, R., Kimboka, S., Issaka, A. I., Baines, S. K., Dibley, M. J., & Agho, K. E. (2015). Determinants of stunting and severe stunting among under-fives in Tanzania: evidence from the 2010 cross-sectional household survey. BMC Pediatrics, 15, 165.

Crognier, E., Baali, A., Hilali, M. K., Villena, M., & Vargas, E. (2006). Preference for sons and sex ratio in two non‐western societies. American Journal of Human Biology: The Official Journal of the Human Biology Association, 18(3), 325-334.

Cronk, L. (1989). Low socioeconomic status and female‐biased parental investment: the Mukogodo example. American Anthropologist, 91(2), 414-429.

Cruz, L. M. G., Azpeitia, G. G., Súarez, D. R., Rodríguez, A. S., Ferrer, J. F. L., & Serra-Majem, L. (2017). Factors Associated with Stunting among Children Aged 0 to 59 Months from the Central Region of Mozambique. Nutrients, 9(5).

Danaei, G., Andrews, K. G., Sudfeld, C. R., Fink, G., McCoy, D. C., Peet, E., Sania, A., Smith Fawzi, M. C., Ezzati, M., & Fawzi, W. W. (2016). Risk Factors for Childhood Stunting in 137 Developing Countries: A Comparative Risk Assessment Analysis at Global, Regional, and Country Levels. PLoS Medicine, 13(11), e1002164.

de Onis, M., & Branca, F. (2016). Childhood stunting: a global perspective. Maternal & Child Nutrition, 12 Suppl 1(Suppl 1), 12–26.

Dorsey, J. L., Manohar, S., Neupane, S., Shrestha, B., Klemm, R. D. W., & West, K. P. J. (2018). Individual, household, and community level risk factors of stunting in children younger than 5 years: Findings from a national surveillance system in Nepal. Maternal & Child Nutrition, 14(1).

Elhoumed, M., Andegiorgish, A. K., Qi, Q., Gebremedhin, M. A., Wang, L., Uwimana, G., Cheng, Y., Zhu, Z., & Zeng, L. (2022). Patterns and Determinants of the Double Burden of Malnutrition Among Adolescents: A 14-Year Follow-Up of a Birth Cohort in Rural China. The Journal of Pediatrics, 242, 48–56.e3. https://doi.org/10.1016/j.jpeds.2021.10.062

Elsmén, E., Hansen Pupp, I., & Hellström-Westas, L. (2004). Preterm male infants need more initial respiratory and circulatory support than female infants. Acta Paediatrica (Oslo, Norway : 1992), 93(4), 529–533.

Ezeh, O. K., Abir, T., Zainol, N. R., Al Mamun, A., Milton, A. H., Haque, M. R., & Agho, K. E. (2021). Trends of Stunting Prevalence and Its Associated Factors among Nigerian Children Aged 0-59 Months Residing in the Northern Nigeria, 2008-2018. Nutrients, 13(12).

Getaneh, Z., Enawgaw, B., Engidaye, G., Seyoum, M., Berhane, M., Abebe, Z., Asrie, F., & Melku, M. (2017). Prevalence of anemia and associated factors among school children in Gondar town public primary schools, northwest Ethiopia: A school-based cross-sectional study. PloS One, 12(12), e0190151.

Gonete, A. T., Kassahun, B., Mekonnen, E. G., & Takele, W. W. (2021). Stunting at birth and associated factors among newborns delivered at the University of Gondar Comprehensive Specialized Referral Hospital. PloS One, 16(1), e0245528.

Grantham-McGregor, S., Cheung, Y. B., Cueto, S., Glewwe, P., Richter, L., Strupp, B., & International Child Development Steering Group. (2007). Developmental potential in the first 5 years for children in developing countries. The lancet, 369(9555), 60-70. https://doi.org/10.1016/S0140-6736(07)60032-4

Green, M. S. (1992). The male predominance in the incidence of infectious diseases in children: a postulated explanation for disparities in the literature. International Journal of Epidemiology, 21(2), 381–386.

Gutema, B., Adissu, W., Asress, Y., & Gedefaw, L. (2014). Anemia and associated factors among school-age children in Filtu Town, Somali region, Southeast Ethiopia. BMC Hematology, 14(1), 13.

Hoddinott, J., Alderman, H., Behrman, J. R., Haddad, L., & Horton, S. (2013). The economic rationale for investing in stunting reduction. Maternal & Child Nutrition, 9 Suppl 2(Suppl 2), 69–82.

Ito, Y. (2005). Golden rules and pitfalls in selecting optimum conditions for high-speed counter-current chromatography. Journal of Chromatography A, 1065(2), 145-168. https://doi.org/10.1016/j.chroma.2004.12.044

Khan, S., Zaheer, S., & Safdar, N. F. (2019). Determinants of stunting, underweight and wasting among children < 5 years of age: evidence from 2012-2013 Pakistan demographic and health survey. BMC Public Health, 19(1), 358.

Kilbride, H. W., & Daily, D. K. (1998). Survival and subsequent outcome to five years of age for infants with birth weights less than 801 grams born from 1983 to 1989. Journal of Perinatology : Official Journal of the California Perinatal Association, 18(2), 102–106.

Kismul, H., Acharya, P., Mapatano, M. A., & Hatløy, A. (2017). Determinants of childhood stunting in the Democratic Republic of Congo: further analysis of Demographic and Health Survey 2013-14. BMC Public Health, 18(1), 74.

Leslie, C. C. (1997). Properties and regulation of cytosolic phospholipase A2. Journal of Biological Chemistry, 272(27), 16709-16712.

Manggala, A. K., Wiswa, K., Kenwa, M., Me, M., Kenwa, L., Agung, A., Dwinaldo, G., Jaya, P., Agung, A., & Sawitri, S. (2018). Paediatrica Indonesiana. 58(5), 205–212.

Martorell, R., Khan, L. K., & Schroeder, D. G. (1994). Reversibility of stunting: epidemiological findings in children from developing countries. European Journal of Clinical Nutrition, 48 Suppl 1, S45–S57.

Mengesha, A., Hailu, S., Birhane, M., & Belay, M. M. (2021). The Prevalence of Stunting and Associated Factors among Children Under Five years of age in Southern Ethiopia: Community Based Cross-Sectional Study. Annals of Global Health, 87(1), 111.

Mesfin, F., Berhane, Y., & Worku, A. (2015). Anemia among Primary School Children in Eastern Ethiopia. PloS One, 10(4), e0123615.

Micha, R., Mannar, V., Afshin, A., Allemandi, L., Baker, P., Battersby, J., Bhutta, Z., Chen, K., Corvalan, C., Di Cesare, M., & others. (2020). 2020 global nutrition report: action on equity to end malnutrition.

Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ, 339.

Mulyaningsih, T., Mohanty, I., Widyaningsih, V., Gebremedhin, T. A., Miranti, R., & Wiyono, V. H. (2021). Beyond personal factors: Multilevel determinants of childhood stunting in Indonesia. PloS One, 16(11), e0260265.

Mzumara, B., Bwembya, P., Halwiindi, H., Mugode, R., & Banda, J. (2018). Factors associated with stunting among children below five years of age in Zambia: evidence from the 2014 Zambia demographic and health survey. BMC Nutrition, 4, 51.

Nkurunziza, S., Meessen, B., Van Geertruyden, J.-P., & Korachais, C. (2017). Determinants of stunting and severe stunting among Burundian children aged 6-23 months: evidence from a national cross-sectional household survey, 2014. BMC Pediatrics, 17(1), 176.

Nutrition, A., & Volume, D. (2021). No Title. 1(1), 34–42.

Paudel, R., Pradhan, B., Rr, W., Dp, P., & Sr, O. (2011). Risk Factors for Stunting Among Children : A Community Based Case Control Study in Nepal.

Perkins, J. M., Kim, R., Krishna, A., McGovern, M., Aguayo, V. M., & Subramanian, S. V. (2017). Understanding the association between stunting and child development in low-and middle-income countries: Next steps for research and intervention. Social Science & Medicine, 193, 101-109. https://doi.org/10.1016/j.socscimed.2017.09.039

Pun, V. C., Dowling, R., & Mehta, S. (2021). Ambient and household air pollution on early-life determinants of stunting-a systematic review and meta-analysis. Environmental Science and Pollution Research International, 28(21), 26404–26412.

Rakotomanana, H., Gates, G. E., Hildebrand, D., & Stoecker, B. J. (2017). Determinants of stunting in children under 5 years in Madagascar. Maternal & Child Nutrition, 13(4).

Ramli, Agho, K. E., Inder, K. J., Bowe, S. J., Jacobs, J., & Dibley, M. J. (2009). Prevalence and risk factors for stunting and severe stunting among under-fives in North Maluku province of Indonesia. BMC Pediatrics, 9, 64.

Shereen, M. A., Khan, S., Kazmi, A., Bashir, N., & Siddique, R. (2020). COVID-19 infection: Emergence, transmission, and characteristics of human coronaviruses. Journal of advanced research, 24, 91-98. https://doi.org/10.1016/j.jare.2020.03.005

Shinsugi, C., Matsumura, M., Karama, M., Tanaka, J., Changoma, M., & Kaneko, S. (2015). Factors associated with stunting among children according to the level of food insecurity in the household: a cross-sectional study in a rural community of Southeastern Kenya. BMC Public Health, 15, 441.

Siswati, S. (2015). Kualitas pelayanan kesehatan dengan kepuasan pasien BPJS di unit rawat inap RSUD Kota Makassar. Media Kesehatan Masyarakat Indonesia, 11(3), 174-183.

Siswati, T. (2019). Risk Factors for Stunting and Severe Stunting among under Five Years Children in Rural Areas in Indonesia. 8(11), 5–9.

Smith, L. C., & Haddad, L. (2015). Reducing child undernutrition: past drivers and priorities for the post-MDG era. World Development, 68, 180–204.

Sserwanja, Q., Kamara, K., Mutisya, L. M., Musaba, M. W., & Ziaei, S. (2021). Rural and Urban Correlates of Stunting Among Under-Five Children in Sierra Leone: A 2019 Nationwide Cross-Sectional Survey. Nutrition and Metabolic Insights, 14, 11786388211047056.

Stevens, G. A., Finucane, M. M., De-Regil, L. M., Paciorek, C. J., Flaxman, S. R., Branca, F., ... & Nutrition Impact Model Study Group. (2013). Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data. The Lancet Global Health, 1(1), e16-e25. https://doi.org/10.1016/S2214-109X(13)70001-9

Sunguya, B. F., Zhu, S., Mpembeni, R., & Huang, J. (2019). Trends in prevalence and determinants of stunting in Tanzania: an analysis of Tanzania demographic health surveys (1991-2016). Nutrition Journal, 18(1), 85.

Svedberg, P. (1990). Undernutrition in Sub‐Saharan Africa: Is there a gender bias?. The Journal of Development Studies, 26(3), 469-486.

Synnes, A. R., Ling, E. W., Whitfield, M. F., Mackinnon, M., Lopes, L., Wong, G., & Effer, S. B. (1994). Perinatal outcomes of a large cohort of extremely low gestational age infants (twenty-three to twenty-eight completed weeks of gestation). The Journal of pediatrics, 125(6), 952-960. https://doi.org/10.1016/S0022-3476(05)82015-3

Tafesse, T., Yoseph, A., Mayiso, K., & Gari, T. (2021). Factors associated with stunting among children aged 6 – 59 months in Bensa District, Sidama Region, South Ethiopia : unmatched case-control study. BMC Pediatrics, 1–11.

Tariku, A., Biks, G. A., Derso, T., Wassie, M. M., & Abebe, S. M. (2017). Stunting and its determinant factors among children aged 6-59 months in Ethiopia. Italian Journal of Pediatrics, 43(1), 112.

Thurstans, S., Sessions, N., Dolan, C., Sadler, K., Cichon, B., Isanaka, S., Roberfroid, D., Stobaugh, H., Webb, P., & Khara, T. (2022). The relationship between wasting and stunting in young children: A systematic review. Maternal & Child Nutrition, 18(1), e13246.

Tiwari, R., Ausman, L. M., & Agho, K. E. (2014). Determinants of stunting and severe stunting among under-fives: evidence from the 2011 Nepal Demographic and Health Survey. BMC Pediatrics, 14, 239.

Torlesse, H., Cronin, A. A., Sebayang, S. K., & Nandy, R. (2016). Determinants of stunting in Indonesian children: evidence from a cross-sectional survey indicate a prominent role for the water, sanitation and hygiene sector in stunting reduction. BMC Public Health, 16, 669.

Unicef/ WHO/The World Bank. (2019). Levels and trends in child malnutrition. Key Findings Pf the 2019 Edition.

UNICEF/WHO/World Bank. (2020). Joint child malnutrition estimates, March 2020 edition. https://data.unicef.org/topic/nutrition/malnutrition/

Victora, C. G., de Onis, M., Hallal, P. C., Blössner, M., & Shrimpton, R. (2010). Worldwide timing of growth faltering: revisiting implications for interventions. Pediatrics, 125(3), e473–e480.

Vonaesch, P., Djorie, S. G., Kandou, K. J. E., Rakotondrainipiana, M., Schaeffer, L., Andriatsalama, P. V., Randriamparany, R., Gondje, B. P., Nigatoloum, S., Vondo, S. S., Etienne, A., Robinson, A., Hunald, F. A., Raharimalala, L., Giles-Vernick, T., Tondeur, L., Randrianirina, F., Bastaraud, A., Gody, J.-C., … Randremanana, R. V. (2021). Factors Associated with Stunted Growth in Children Under Five Years in Antananarivo, Madagascar and Bangui, Central African Republic. Maternal and Child Health Journal, 25(10), 1626–1637.

Vonaesch, P., Tondeur, L., Breurec, S., Bata, P., Nguyen, L. B. L., Frank, T., Farra, A., Rafaï, C., Giles-Vernick, T., Gody, J. C., Gouandjika-Vasilache, I., Sansonetti, P., & Vray, M. (2017). Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA). PloS One, 12(8), e0182363.

Wali, N., Agho, K. E., & Renzaho, A. M. N. (2020). Factors Associated with Stunting among Children under 5 Years in Five South Asian Countries (2014-2018): Analysis of Demographic Health Surveys. Nutrients, 12(12).

Wamani, H., Astrøm, A. N., Peterson, S., Tumwine, J. K., & Tylleskär, T. (2007). Boys are more stunted than girls in sub-Saharan Africa: a meta-analysis of 16 demographic and health surveys. BMC Pediatrics, 7, 17.

Widyaningsih, V., Mulyaningsih, T., Rahmawati, F. N., & Adhitya, D. (2022). Determinants of socioeconomic and rural-urban disparities in stunting: evidence from Indonesia. Rural and Remote Health, 22(1), 7082.

Woldehanna, T., Behrman, J. R., & Araya, M. W. (2017). The effect of early childhood stunting on children’s cognitive achievements: Evidence from young lives Ethiopia. The Ethiopian Journal of Health Development = Ya’Ityopya Tena Lemat Mashet, 31(2), 75–84.

World Health Organization. (2011). Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity,” in Vitamin and Mineral Nutrition Information System.

World Health Organization. (2014). Global nutrition targets 2025: Stunting policy brief.

World Health Organization. (2020). Stunting in Nutshell.

Yang, Y. Y., Kaddu, G., Ngendahimana, D., Barkoukis, H., Freedman, D., Lubaale, Y. A., Mupere, E., & Bakaki, P. M. (2018). Trends and determinants of stunting among under-5s: evidence from the 1995, 2001, 2006 and 2011 Uganda Demographic and Health Surveys. Public Health Nutrition, 21(16), 2915–2928.

Yu, N., Li, W., Kang, Q., Xiong, Z., Wang, S., Lin, X., ... & Wu, J. (2020). Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. The Lancet Infectious Diseases, 20(5), 559-564. https://doi.org/10.1016/S1473-3099(20)30176-6