To determine the microbial profile of catheter related sepsis in ICU

https://doi.org/10.53730/ijhs.v6nS8.13294

Authors

  • Rajesh Gera MBBS, MD (Internal medicine), Senior Consultant, Paras hospital, Panchkula, Haryana
  • Phool Kanwar Singh Brar MBBS, MD, IDCCM, I.C.U. Director, Department of Critical Care, Park Healing Touch Hospital, Ambala

Keywords:

blood stream infection, peripheral venous catheter, septicemia

Abstract

Background: Intravenous catheter-related blood stream infections (PVC-BSIs) are one of the common causes of death and illness in hospitals worldwide. Failure to practice adequate aseptic techniques is a leading cause of blood stream infections caused by catheters. The aim of this study to identify the microbiological makeup of catheter-related sepsis in the intensive care unit. Materials and methods: Participants comprised all intensive care unit (ICU) inpatients who had a peripheral venous catheter (PVC) implanted and who showed symptoms of septicemia within 48 hours after PVC implantation. Kirby-Brauer disc diffusion technique was used to test the antibiotic susceptibility of the bacterial isolates, as recommended by the CLSI. Results: Twenty percent of patients had identical bacterial growth in PVC tip cultures and blood cultures, suggesting peripheral venous catheter-related bloodstream infection (PVC- BSI), while twenty-five percent of patients were colonised and thirty percent of patients had bloodstream infections unrelated to the catheter. For one-quarter of patients, (25%) no organism development was identified. Among the 20 patients diagnosed with PVC-BSI, 8 (40%) were found to have infections caused by Staphylococcus aureus, 4 (20%) by Klebsiella species, 4 (20%) by CONS, 2 (10%) by Enterococcus species, and 1 (5%) by both Acinetobacter and Pseudomonas species. 

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References

Almuneef MA, Memish ZA, Balkhy HH, Hijari O, Canningham G, Francis C. Rate, risk factors and outcomes of catheter-related bloodstream infection in a paedriatic intensive care unit in Saudi Arabia. J Parenter Enteral Nutr. 2007;31:284-7.

CDC guideline for the prevention of intravenous catheter-related infection, 2011. Available at https://www.ajicjournal.org/article/S0196- 6553(11)00085- X/fulltext

CLSI. Performance standard for antimicrobial susceptibility testing; Twenty-fifth informational supplement. CLSI document M100-S25 (ISBN 1- 56238-989-0). Available at file:///C:/Users/medip/Downloads/CLSI_2015.pdf

Donlan RM. Biofilms and device-associated infections. Emerg Infect Dis.2001Mar- Apr;7(2):277-81.

Gahlot R, Nigam C, Kumar V, Gupta M. Catheter related blood stream infections in ICU: A study from North India. Int J Infect Control. 2013 May 20;9(2).

Henry M, York MK, Thomson RB. Catheter tip cultures; Clinical microbiology procedures handbook. 2nd ed. 2007.

Karpel E, Kunsdorf-Wnuk A, Musioł E, Skorupa A, Arct-Danielak D, Jarosz U. Catheter related blood stream infectionin ICU patients with prolonged central venous catheterisation--cause and prevention. Pol Merkur Lekarski. 2006;21(123):211-7.

Meadows C, Creagh-Brown B, Nia T, Bonnici K, Finney S. Definition of catheter- related bloodstream infection as a quality improvement measure in intensive care. Crit Care. 2009;13:191.

Mermel LA, Allon M, Bouza E ET AL. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2009 Jul 1;49(1):1-45. doi: 10.1086/599376

Mermel LA. Prevention of intravascular catheter- related infections. Ann Intern Med. 2000;132:391- 402.

National Nosocomial Infection Surveillance System (NNIS). System report, data ssummary from January 1992 through June 2004, issued Oct 2004. Am J Infect Control. 2004;32:470-85.

O'grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG et al. Guidelines for the Prevention of Intravascular Catheter-Related Infections. MMWR. 2002;51.

Parameswaran R, Sherchan JB, Varma D M, Mukhopadhyay C, Vidyasagar S. Intranenous catheter-related infection in an Indian tertiary care hospital. J Infect Dev Ctries. 2011 Jul 4;5(6):452-8

Pujol M, Hornero A, Saballs M, Argerich MJ, Verdaguer R, Cisnal M, et al. Clinical epidemiology and outcomes of peripheral venous catheter-related bloodstream infections at a university-affiliated hospital. J Hosp Infect. 2007;67:22-9.

Sato A, Nakamura I, Fujita H, Tsukimori A, Kobayashi T, Fukushima S et al. Peripheral venous catheter-related bloodstream infection is associated with severe complications and potential death: a retrospective observational study. BMC Infect Dis. 2017 Dec;17(1):434

Siegman-Igra Y, Anglim AM, Shapiro DE, Adal KA, Strain BA, Farr BM. Diagnosis of vascular catheter-related bloodstream infection: a meta- analysis. J Clin Microbiol. 1997 Apr;35(4):928-36.

Thomas D, Parameswaran N, Harish BN. Catheter related blood stream infections in the paediatric intensive care unit: A descriptive study. Indian J Crit Care Med. 2013 May;17(3):135.

Tullu MS, Deshmukh CT, Baveja SM. Bacterial profile andantimicrobial susceptibility pattern in catheter related nosocomial infection. J Postgrad Med. 1998;44(1): 7-13.11.

Published

08-10-2022

How to Cite

Gera, R., & Brar, P. K. S. (2022). To determine the microbial profile of catheter related sepsis in ICU. International Journal of Health Sciences, 6(S8), 4757–4764. https://doi.org/10.53730/ijhs.v6nS8.13294

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