Mucin2 protein (MUC2), ghrelin (GHRL) and obestatin (OB) as physiological biomarkers in patients infected with Giardia lamblia parasite

Shahad Dakhel Khalaf; Haider Abbas Hadi; Ali Yas Khudair; Rasha Saad Toma

doi:10.53730/ijhs.v6nS10.13319

Authors

Shahad Dakhel Khalaf College of Pharmacy/ University of Kerbala
Haider Abbas Hadi Faculty of Medical Technology, The Islamic University
Ali Yas Khudair Faculty of Medical Technology, The Islamic University
Rasha Saad Toma Faculty of Science, University of Kufa

Keywords:

giardiasis, diarrhea, MUC2, GHRL, OB, Iraq

Abstract

The study was conducted on 400 suspected patients and twenty-four healthy persons, who visited the laboratory of AL-Hakeem hospital and AL-Zahra maternity and pediatrics in AL-Najaf province from October till May 2018. This study was designed to determine the effects of Giardia lamblia infection on some biomarkers such as (mucin-2 protein (MUC2), ghrelin (GHRL), and obestatin (OB).whereas the numbers and percentage of the infected patient were 48 (12%) vary with different gender;28 (7%) male and 20 (5%), The result of the study revealed that concentration of (MUC2),(GHRL) and (OB) in male and female patients infected with G. lamblia significantly increased (P<0.05) is compared to the control group. Also, it revealed a significant increase (P in concentrations in the total number of patients infected with G. lamblia and the control group. The current study has concluded that the infection with G .lamblia affects some immunological and physiological markers of humans represented by (mucin-2 protein (MUC2), ghrelin (GHRL), and obestatin (OB) as good biomarkers which may be used in the detection of G .lamblia parasite.

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