A cross sectional study on the relationship between serum calcium level and severity of dengue fever
Keywords:
Serum calcium level, Severity of dengue fever, A cross sectional studyAbstract
Background: Dengue is the most rapidly spreading mosquito borne disease in the world. An estimated 50 million dengue infections occur annually. It is caused by a small, single stranded RNA virus belonging to the genus Flavivirus, family Flaviviridae and is divided into four serotypes (DEN-1 to DEN-4). These various serotypes are transmitted to humans through the bites of infected Aedes mosquitoes, primarily Aedes aegypti. Materials & Methods: A cross sectional study was conducted on 72 patients with dengue fever, for a period of 12 months in the medicine wards of Government Medical College, Kottayam. All cases fulfilling the inclusion criteria during the study period were included after SRC and IRB approval. Results: Mean age of patients in the present study was 32.6 in dengue fever and 32.1 in severe dengue. There was no significant correlation between age and serum corrected calcium level (Pearson correlation coefficient – 0.074, p value 0.539). In patients with dengue fever, mean hematocrit was 39.2 %, while in those with severe dengue, it was 40.5 %. There was no significant correlation between hematocrit and serum corrected calcium level (Pearson correlation coefficient – 0.147, p value 0.219).
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Chambers TJ, Hahn CS, Galler R, Rice CM (1990) Flavivirus genome organization, expression, and replication. Annu Rev Microbiol 44: 649-688.
World Health Organization. Dengue guidelines for diagnosis, prevention, treatment and control, New edition. Geneva: WHO; 2009.
Balmaseda A et al. Assessment of the World Health Organization scheme for classification of dengue severity in Nicaragua. American Journal of Tropical Medicine and Hygiene, 2005, 73:1059–1062.
Phuong CX, Nhan NT, Kneen R, et al. Clinical diagnosis and assessment of severity of Confirmed dengue infections in Vietnamese children: is the World Health Organization classification system helpful? Am J Trop Med Hyg 2004; 70(2): 172-9.
Zaloga GP, Chernow B. The multifactorial basis for hypocalcemia during sepsis. Studies of the parathyroid hormone vitamin D axis. Ann Intern Med 1987;107:36 41.
Uddin KN, Musa AKM, Haque Wasim Md, Sarker RSC, Ahmed AKMS. A follow up on biochemical parameters in dengue patients attending BIRDEM hospital. Ibrahim Med Coll. J. 2008; 2(1): 25–7.
Murugan M.R., M. Gopalakrishna Pillai. Hypocalcemia : A Marker of Severe Dengue. Amrita Journal of Medicine. 2016; 12(1):25-29.
Mahajan A, Shetty IN. A Study on Correlation between Serum Ionized Calcium and Severity of Dengue Infection. IOSR J Dent Med Sci. 2019 Mar;18(3):44–52.
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