Analysis of results of volatile organic compound (VOC) measurements using breathanalyzer on COVID-19 confirmed patients with pneumonia and without pneumonia

Caesar Ensang Timuda; Susanthy Djajalaksana; Jani Jane Rosihaningsih Sugiri; Arinto Yudi Ponco Wardoyo; Heri Sutanto

doi:10.53730/ijhs.v6nS9.13506

Authors

Caesar Ensang Timuda
caesar.ensang.timuda@gmail.com
Department of Pulmonology and Respiratory, Faculty of Medicine, Brawijaya, University, Saiful Anwar Hospital, Indonesia, 65112.
Susanthy Djajalaksana Department of Pulmonology and Respiratory, Faculty of Medicine, Brawijaya, University, Saiful Anwar Hospital, Indonesia, 65112.
Jani Jane Rosihaningsih Sugiri Department of Pulmonology and Respiratory, Faculty of Medicine, Brawijaya, University, Saiful Anwar Hospital, Indonesia, 65112.
Arinto Yudi Ponco Wardoyo Departement of Physics, Faculty of Mathematics and Natural Sciences, Brawijaya University, Saiful Anwar Hospital, Indonesia, 65112.
Heri Sutanto Departement of Internal Medicine, Faculty of Medicine, Brawijaya, University, Saiful Anwar Hospital, Indonesia, 65112.

Keywords:

VOC, COVID-19, Pneumonia, anxiety and COVID-19

Abstract

WHO declared COVID-19 infection as a pandemic since 2020. A rapid noninvasive examination is needed for screening and diagnostic. Exhaled Volatile Organic Compound (VOC) is a sample directly connected to the affected organ, which is the lung, and can be measured as an endogenous volatile marker resulted from oxidative stress. This study aims to analyze differences in VOC concentration in COVID-19 patients with pneumonia and without pneumonia. This Case Control Study used 93 confirmed case samples of COVID-19 and 42 healthy subject. Demographic and clinical data taken from anamnesis and/or medical records. VOC’s data of respiratory track are taken through the exhalation air in a bag and analyzed with breathanalyzer. Statistical analysis was conducted using Mann-Whitney test. In the analysis of confirmed samples of COVID-19 between pneumonia and without pneumonia, co components were found to affect the incidence of pneumonia in confirmed samples of COVID-19 (p=0.003). This conclusion is Components of CO in confirmed COVID-19 have a meaningful effect on an event of pneumonia.

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