Deep anterior lamellar keratoplasty in keratoconus
Keywords:
DALK, Average Keratometry, keratoconus, Topography, astigmatism, BCVAAbstract
Aims: To analyse the outcome of DALK in patients with keratoconus in terms of best corrected and uncorrected visual acuity, average K and topographic astigmatism. Settings and design: Prospective interventional case series study Material and methods: 28 eyes of 28 patients diagnosed with keratoconus were evaluated from August 2009 – July 2011 in a tertiary eye care hospital. All patients underwent DALK and outcomes were assessed on 4 parameters: Average Keratometric reading, topographic astigmatism, UCVA and BCVA alongwith epidemiological analysis. Statistical analysis used: ANOVA testing and Dunnett multiple comparison test. Results: We had evaluated 28 eyes of 28patients (10 males and 18 females) in the age group of 15 to 35 years. Cases were classified as moderate (4) and severe (24) category. There was a statistical significant decrease Average K and Topographic Astigmatism in post op period which was evaluated at 1, 3 and 6 months. (p value <0.05). From the sample size, allof the patients showed improvement in visual acuity by more than one Snellens. No significant post operative complications occurred. Conclusion: DALK is a safe and effective treatment for severe keratoconus, corneal scarring and contact lens intolerance.
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Al-Torbak AA, Al- Motowa S, Al- Assiri A et al. Deep anterior lamellar keratolasty for keratoconus. Cornea 2006;25:408-412.
Bahar I, Kaisermann I, Srinivasan S et al. Comparison of three different techniques of corneal transplantation for keratoconus. Am J Ophthalmol 2008; 146: 905 – 912
Descemetic versus pre-descemetic lamellar keratoplasty: clinical and confocal study. Abdelkader A1, Kaufman HE 2011 Nov;30(11):1244-52. doi: 10.1097/ICO.0b013e318219bc1a.
Epidemiology of keratoconus - Gokhale Nikhil S,Year : 2013 | Volume: 61 | Issue Number: 8 | Page: 382-383 Indian Journal of Ophthalmology
Fogla R, Padmanabhan P. Results of deep lamellar keratoplasty using the big bubble technique in patients with keratoconus. Am J Ophthalmol. 2006;141: 254-259
Fontana L, Parente G, Tassinari G. Clinial outcomes after deep anterior lamellar keratoplasty using the big bubble technique in patients with keratoconus. Am J Ophthal. 2007 Jan;143(1):117 – 124
Intraoperative Optical Coherence Tomography for Enhanced Depth Visualization in Deep Anterior Lamellar Keratoplasty from the PIONEER Study John Au, Jeffrey Goshe, William J. Dupps, Jr., Sunil K. Srivastava, Justis P. Ehlers, Cornea. Author manuscript; available in PMC 2016 Sep 1.Cornea. 2015 Sep; 34(9):10391043. doi: 10.1097/ICO.0000000000000508
J K Reddy. Y Umesh, Clinical outcomes after DALK in patients with keratoconus, AIOC Proceedings 2008, cornea session iii, page 195
Kubaloglu A, Koytak A, Sari ES, Akyol S et al. Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A four year comparative study. Indian J ophthalmol. 2012 Jan – Feb;60(1):35-40
Kymionis, G.D., Grentzelos, M.A., Petrelli, M. et al. Burr-Assisted Anterior Lamellar Keratoplasty (DALK) in Patients with Corneal Stromal Scarring: A Case Series. Ophthalmol Ther (2020). https://doi.org/10.1007/s40123-020-00248-8
Kymionis, Portaliou DM, Bouzoukis DI, Suh LH et al. Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus. JCRS 2007;33(11):1982-4
Reinhart WJ, Musch DC, Jacobs DS, Lee WB, Kaufman SC, Shtein RM. Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty a report by the american academy of ophthalmology. Ophthalmology. 2011;118(1):209–18. doi: 10.1016/j.ophtha.2010.11.002.
Richard JM, Paton D, Gasset AR. A comparison of penetrating and lamellar keratoplasty in the surgical management of keratoconus. Am J Ophthalmol 1978;86:807-11
Van Djik K, Parker J, Tong CM, et al. Midstromal isolated Bowmann layer graft for reduction of advanced keratoconus : a technique to postpone penetrating or deep anterior lamellar keratoplasty. JAMA ophthalmol. 2014;133 (4) 495-501.
Watson SL Ramsay A Dart JK Bunce C Craig E . Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus. Ophthalmology. 2004;111:1676–1682.
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